486 related articles for article (PubMed ID: 30411639)
1. In silico study directed towards identification of novel high-affinity inhibitors targeting an oncogenic protein: BRD4-BD1.
Tumdam R; Kumar A; Subbarao N; Balaji BS
SAR QSAR Environ Res; 2018 Dec; 29(12):975-996. PubMed ID: 30411639
[TBL] [Abstract][Full Text] [Related]
2. Molecular docking and dynamics simulation study of flavonoids as BET bromodomain inhibitors.
Raj U; Kumar H; Varadwaj PK
J Biomol Struct Dyn; 2017 Aug; 35(11):2351-2362. PubMed ID: 27494802
[TBL] [Abstract][Full Text] [Related]
3. A computational insight into binding modes of inhibitors XD29, XD35, and XD28 to bromodomain-containing protein 4 based on molecular dynamics simulations.
Su J; Liu X; Zhang S; Yan F; Zhang Q; Chen J
J Biomol Struct Dyn; 2018 Apr; 36(5):1212-1224. PubMed ID: 28466681
[TBL] [Abstract][Full Text] [Related]
4. Investigation of novel ligand targeting bromodomain-containing protein 4 (BRD4) for cancer drug discovery: complete pharmacophore approach.
Shanmugam V; Muthukrishnan S
J Biomol Struct Dyn; 2023; 41(23):14524-14539. PubMed ID: 36841551
[TBL] [Abstract][Full Text] [Related]
5. A theoretical insight into selectivity of inhibitors toward two domains of bromodomain-containing protein 4 using molecular dynamics simulations.
Su J; Liu X; Zhang S; Yan F; Zhang Q; Chen J
Chem Biol Drug Des; 2018 Mar; 91(3):828-840. PubMed ID: 29139214
[TBL] [Abstract][Full Text] [Related]
6. Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
Yu Z; Ku AF; Anglin JL; Sharma R; Ucisik MN; Faver JC; Li F; Nyshadham P; Simmons N; Sharma KL; Nagarajan S; Riehle K; Kaur G; Sankaran B; Storl-Desmond M; Palmer SS; Young DW; Kim C; Matzuk MM
Proc Natl Acad Sci U S A; 2021 Mar; 118(9):. PubMed ID: 33637650
[TBL] [Abstract][Full Text] [Related]
7. Structure-based virtual screening of novel, high-affinity BRD4 inhibitors.
Muvva C; Singam ER; Raman SS; Subramanian V
Mol Biosyst; 2014 Jul; 10(9):2384-97. PubMed ID: 24976024
[TBL] [Abstract][Full Text] [Related]
8. Importance of a crystalline water network in docking-based virtual screening: a case study of BRD4.
Zhong H; Wang Z; Wang X; Liu H; Li D; Liu H; Yao X; Hou T
Phys Chem Chem Phys; 2019 Dec; 21(45):25276-25289. PubMed ID: 31701109
[TBL] [Abstract][Full Text] [Related]
9. Identification of potent BRD4-BD1 inhibitors using classical and steered molecular dynamics based free energy analysis.
Gupta A; Purohit R
J Cell Biochem; 2024 Mar; 125(3):e30532. PubMed ID: 38317535
[TBL] [Abstract][Full Text] [Related]
10. Pyronaridine as a Bromodomain-Containing Protein 4-
Ibrahim MAA; Abdelhamid MMH; Abdeljawaad KAA; Abdelrahman AHM; Mekhemer GAH; Sidhom PA; Sayed SRM; Paré PW; Hegazy MF; Shoeib T
Molecules; 2023 Jul; 28(15):. PubMed ID: 37570684
[TBL] [Abstract][Full Text] [Related]
11. Pharmacophore-based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors.
Yan G; Hou M; Luo J; Pu C; Hou X; Lan S; Li R
Chem Biol Drug Des; 2018 Feb; 91(2):478-490. PubMed ID: 28901664
[TBL] [Abstract][Full Text] [Related]
12. Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.
Jung M; Philpott M; Müller S; Schulze J; Badock V; Eberspächer U; Moosmayer D; Bader B; Schmees N; Fernández-Montalván A; Haendler B
J Biol Chem; 2014 Mar; 289(13):9304-19. PubMed ID: 24497639
[TBL] [Abstract][Full Text] [Related]
13. In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4.
Rodríguez Y; Gerona-Navarro G; Osman R; Zhou MM
Proteins; 2020 Mar; 88(3):414-430. PubMed ID: 31587361
[TBL] [Abstract][Full Text] [Related]
14. The binding mechanism of NHWD-870 to bromodomain-containing protein 4 based on molecular dynamics simulations and free energy calculation.
Shi M; He J; Weng T; Shi N; Qi W; Guo Y; Chen T; Chen L; Xu D
Phys Chem Chem Phys; 2022 Feb; 24(8):5125-5137. PubMed ID: 35156677
[TBL] [Abstract][Full Text] [Related]
15. Attach-Pull-Release Calculations of Ligand Binding and Conformational Changes on the First BRD4 Bromodomain.
Heinzelmann G; Henriksen NM; Gilson MK
J Chem Theory Comput; 2017 Jul; 13(7):3260-3275. PubMed ID: 28564537
[TBL] [Abstract][Full Text] [Related]
16. Binding Kinetics versus Affinities in BRD4 Inhibition.
Kuang M; Zhou J; Wang L; Liu Z; Guo J; Wu R
J Chem Inf Model; 2015 Sep; 55(9):1926-35. PubMed ID: 26263125
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and biological evaluation of benzo[cd]indol-2(1H)-ones derivatives as BRD4 inhibitors.
Feng Y; Xiao S; Chen Y; Jiang H; Liu N; Luo C; Chen S; Chen H
Eur J Med Chem; 2018 May; 152():264-273. PubMed ID: 29730189
[TBL] [Abstract][Full Text] [Related]
18. Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites.
Olp MD; Sprague DJ; Goetz CJ; Kathman SG; Wynia-Smith SL; Shishodia S; Summers SB; Xu Z; Statsyuk AV; Smith BC
ACS Chem Biol; 2020 Apr; 15(4):1036-1049. PubMed ID: 32149490
[TBL] [Abstract][Full Text] [Related]
19. Structure investigation, enrichment analysis and structure-based repurposing of FDA-approved drugs as inhibitors of BET-BRD4.
Wakchaure P; Velayutham R; Roy KK
J Biomol Struct Dyn; 2019 Aug; 37(12):3048-3057. PubMed ID: 30079805
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays.
Sun Z; Zhang H; Chen Z; Xie Y; Jiang H; Chen L; Ding H; Zhang Y; Jiang H; Zheng M; Luo C
Bioorg Med Chem Lett; 2017 May; 27(9):2003-2009. PubMed ID: 28347667
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]