These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 30412050)

  • 1. Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the
    Riahi Y; Israeli T; Yeroslaviz R; Chimenez S; Avrahami D; Stolovich-Rain M; Alter I; Sebag M; Polin N; Bernal-Mizrachi E; Dor Y; Cerasi E; Leibowitz G
    Elife; 2018 Nov; 7():. PubMed ID: 30412050
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes.
    Balboa D; Saarimäki-Vire J; Borshagovski D; Survila M; Lindholm P; Galli E; Eurola S; Ustinov J; Grym H; Huopio H; Partanen J; Wartiovaara K; Otonkoski T
    Elife; 2018 Nov; 7():. PubMed ID: 30412052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Improvement of ER stress-induced diabetes by stimulating autophagy.
    Bachar-Wikstrom E; Wikstrom JD; Kaiser N; Cerasi E; Leibowitz G
    Autophagy; 2013 Apr; 9(4):626-8. PubMed ID: 23380813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes.
    Bachar-Wikstrom E; Wikstrom JD; Ariav Y; Tirosh B; Kaiser N; Cerasi E; Leibowitz G
    Diabetes; 2013 Apr; 62(4):1227-37. PubMed ID: 23274896
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proinsulin atypical maturation and disposal induces extensive defects in mouse Ins2+/Akita β-cells.
    Yuan Q; Tang W; Zhang X; Hinson JA; Liu C; Osei K; Wang J
    PLoS One; 2012; 7(4):e35098. PubMed ID: 22509386
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.
    Wright J; Birk J; Haataja L; Liu M; Ramming T; Weiss MA; Appenzeller-Herzog C; Arvan P
    J Biol Chem; 2013 Oct; 288(43):31010-8. PubMed ID: 24022479
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.
    Arunagiri A; Haataja L; Cunningham CN; Shrestha N; Tsai B; Qi L; Liu M; Arvan P
    Ann N Y Acad Sci; 2018 Apr; 1418(1):5-19. PubMed ID: 29377149
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.
    Sun J; Cui J; He Q; Chen Z; Arvan P; Liu M
    Mol Aspects Med; 2015 Apr; 42():105-18. PubMed ID: 25579745
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations.
    Wang H; Saint-Martin C; Xu J; Ding L; Wang R; Feng W; Liu M; Shu H; Fan Z; Haataja L; Arvan P; Bellanné-Chantelot C; Cui J; Huang Y
    Mol Cell Endocrinol; 2020 Dec; 518():111025. PubMed ID: 32916194
    [TBL] [Abstract][Full Text] [Related]  

  • 10. YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress.
    De Franco E; Lytrivi M; Ibrahim H; Montaser H; Wakeling MN; Fantuzzi F; Patel K; Demarez C; Cai Y; Igoillo-Esteve M; Cosentino C; Lithovius V; Vihinen H; Jokitalo E; Laver TW; Johnson MB; Sawatani T; Shakeri H; Pachera N; Haliloglu B; Ozbek MN; Unal E; Yıldırım R; Godbole T; Yildiz M; Aydin B; Bilheu A; Suzuki I; Flanagan SE; Vanderhaeghen P; Senée V; Julier C; Marchetti P; Eizirik DL; Ellard S; Saarimäki-Vire J; Otonkoski T; Cnop M; Hattersley AT
    J Clin Invest; 2020 Dec; 130(12):6338-6353. PubMed ID: 33164986
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin.
    Hartley T; Siva M; Lai E; Teodoro T; Zhang L; Volchuk A
    BMC Cell Biol; 2010 Jul; 11():59. PubMed ID: 20659334
    [TBL] [Abstract][Full Text] [Related]  

  • 12. INS-gene mutations: from genetics and beta cell biology to clinical disease.
    Liu M; Sun J; Cui J; Chen W; Guo H; Barbetti F; Arvan P
    Mol Aspects Med; 2015 Apr; 42():3-18. PubMed ID: 25542748
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of proinsulin misfolding on β-cell dynamics, differentiation and function in diabetes.
    Riahi Y; Israeli T; Cerasi E; Leibowitz G
    Diabetes Obes Metab; 2018 Sep; 20 Suppl 2():95-103. PubMed ID: 30230182
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacological Inhibition of Inositol-Requiring Enzyme 1α RNase Activity Protects Pancreatic Beta Cell and Improves Diabetic Condition in Insulin Mutation-Induced Diabetes.
    Herlea-Pana O; Eeda V; Undi RB; Lim HY; Wang W
    Front Endocrinol (Lausanne); 2021; 12():749879. PubMed ID: 34675883
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1.
    Bachar E; Ariav Y; Ketzinel-Gilad M; Cerasi E; Kaiser N; Leibowitz G
    PLoS One; 2009; 4(3):e4954. PubMed ID: 19305497
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bax Inhibitor-1 preserves pancreatic β-cell proteostasis by limiting proinsulin misfolding and programmed cell death.
    Blanc M; Habbouche L; Xiao P; Lebeaupin C; Janona M; Vaillant N; Irondelle M; Gilleron J; Murcy F; Rousseau D; Luci C; Barouillet T; Marchetti S; Lacas-Gervais S; Yvan-Charvet L; Gual P; Cardozo AK; Bailly-Maitre B
    Cell Death Dis; 2024 May; 15(5):334. PubMed ID: 38744890
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes through mitigation of oxidative and ER stress.
    Shyr ZA; Yan Z; Ustione A; Egan EM; Remedi MS
    PLoS One; 2022; 17(2):e0258054. PubMed ID: 35180212
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.
    Haataja L; Manickam N; Soliman A; Tsai B; Liu M; Arvan P
    Diabetes; 2016 Apr; 65(4):1050-60. PubMed ID: 26822090
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PERK (EIF2AK3) regulates proinsulin trafficking and quality control in the secretory pathway.
    Gupta S; McGrath B; Cavener DR
    Diabetes; 2010 Aug; 59(8):1937-47. PubMed ID: 20530744
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biosynthesis, structure, and folding of the insulin precursor protein.
    Liu M; Weiss MA; Arunagiri A; Yong J; Rege N; Sun J; Haataja L; Kaufman RJ; Arvan P
    Diabetes Obes Metab; 2018 Sep; 20 Suppl 2(Suppl 2):28-50. PubMed ID: 30230185
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.