These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 30412832)

  • 1. Novel glucopyranoside C2-derived 1,2,3-triazoles displaying selective inhibition of O-GlcNAcase (OGA).
    Igual MO; Nunes PSG; da Costa RM; Mantoani SP; Tostes RC; Carvalho I
    Carbohydr Res; 2019 Jan; 471():43-55. PubMed ID: 30412832
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinctive inhibition of O-GlcNAcase isoforms by an alpha-GlcNAc thiolsulfonate.
    Kim EJ; Amorelli B; Abdo M; Thomas CJ; Love DC; Knapp S; Hanover JA
    J Am Chem Soc; 2007 Dec; 129(48):14854-5. PubMed ID: 17994748
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a specific inhibitor of nOGA - a caspase-3 cleaved O-GlcNAcase variant during apoptosis.
    Li J; Li Z; Li T; Lin L; Zhang Y; Guo L; Xu Y; Zhao W; Wang P
    Biochemistry (Mosc); 2012 Feb; 77(2):194-200. PubMed ID: 22348480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elevation of cellular O-GlcNAcylation level by a potent and selective O-GlcNAcase inhibitor based on tetrahydroimidazopyridine scaffold.
    Li T; Li Z; Li J; Wang J; Guo L; Wang PG; Zhao W
    Bioorg Med Chem Lett; 2012 Nov; 22(22):6854-7. PubMed ID: 23058883
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation.
    Dorfmueller HC; Borodkin VS; Schimpl M; van Aalten DM
    Biochem J; 2009 May; 420(2):221-7. PubMed ID: 19275764
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of O-GlcNAcase inhibitors via 'click chemistry' and biological evaluations.
    Li T; Guo L; Zhang Y; Wang J; Li Z; Lin L; Zhang Z; Li L; Lin J; Zhao W; Li J; Wang PG
    Carbohydr Res; 2011 Jul; 346(9):1083-92. PubMed ID: 21514574
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders.
    Martínez-Viturro CM; Trabanco AA; Royes J; Fernández E; Tresadern G; Vega JA; Del Cerro A; Delgado F; García Molina A; Tovar F; Shaffer P; Ebneth A; Bretteville A; Mertens L; Somers M; Alonso JM; Bartolomé-Nebreda JM
    J Med Chem; 2020 Nov; 63(22):14017-14044. PubMed ID: 33197187
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MK-8719, a Novel and Selective
    Wang X; Li W; Marcus J; Pearson M; Song L; Smith K; Terracina G; Lee J; Hong KK; Lu SX; Hyde L; Chen SC; Kinsley D; Melchor JP; Rubins DJ; Meng X; Hostetler E; Sur C; Zhang L; Schachter JB; Hess JF; Selnick HG; Vocadlo DJ; McEachern EJ; Uslaner JM; Duffy JL; Smith SM
    J Pharmacol Exp Ther; 2020 Aug; 374(2):252-263. PubMed ID: 32493725
    [TBL] [Abstract][Full Text] [Related]  

  • 9. O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice.
    Makino A; Dai A; Han Y; Youssef KD; Wang W; Donthamsetty R; Scott BT; Wang H; Dillmann WH
    Am J Physiol Cell Physiol; 2015 Nov; 309(9):C593-9. PubMed ID: 26269457
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Defining the structural origin of the substrate sequence independence of O-GlcNAcase using a combination of molecular docking and dynamics simulation.
    Martin JC; Fadda E; Ito K; Woods RJ
    Glycobiology; 2014 Jan; 24(1):85-96. PubMed ID: 24134879
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glycosyl triazoles as novel insect β-N-acetylhexosaminidase OfHex1 inhibitors: Design, synthesis, molecular docking and MD simulations.
    Dong L; Shen S; Chen W; Lu H; Xu D; Jin S; Yang Q; Zhang J
    Bioorg Med Chem; 2019 Jun; 27(12):2315-2322. PubMed ID: 30528165
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice.
    Hastings NB; Wang X; Song L; Butts BD; Grotz D; Hargreaves R; Fred Hess J; Hong KK; Huang CR; Hyde L; Laverty M; Lee J; Levitan D; Lu SX; Maguire M; Mahadomrongkul V; McEachern EJ; Ouyang X; Rosahl TW; Selnick H; Stanton M; Terracina G; Vocadlo DJ; Wang G; Duffy JL; Parker EM; Zhang L
    Mol Neurodegener; 2017 May; 12(1):39. PubMed ID: 28521765
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases.
    Dorfmueller HC; Borodkin VS; Schimpl M; Zheng X; Kime R; Read KD; van Aalten DM
    Chem Biol; 2010 Nov; 17(11):1250-5. PubMed ID: 21095575
    [TBL] [Abstract][Full Text] [Related]  

  • 14. O-GlcNAcase: Emerging Mechanism, Substrate Recognition and Small-Molecule Inhibitors.
    Elbatrawy AA; Kim EJ; Nam G
    ChemMedChem; 2020 Jul; 15(14):1244-1257. PubMed ID: 32496638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tautomeric modification of GlcNAc-thiazoline.
    Knapp S; Abdo M; Ajayi K; Huhn RA; Emge TJ; Kim EJ; Hanover JA
    Org Lett; 2007 Jun; 9(12):2321-4. PubMed ID: 17508759
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of O-GlcNAcase in perfused rat hearts by NAG-thiazolines at the time of reperfusion is cardioprotective in an O-GlcNAc-dependent manner.
    Laczy B; Marsh SA; Brocks CA; Wittmann I; Chatham JC
    Am J Physiol Heart Circ Physiol; 2010 Nov; 299(5):H1715-27. PubMed ID: 20833964
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isoindoline-based fluorogenic probes bearing a self-immolative linker for the sensitive and selective detection of O-GlcNAcase activity.
    Wu YH; Wang GJ; Guo C; Wang PP; Wang JY; Hu XL; Zang Y; James TD; Li J; He XP
    Chem Commun (Camb); 2024 Aug; 60(63):8240-8243. PubMed ID: 39007923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels.
    Dorfmueller HC; Borodkin VS; Schimpl M; Shepherd SM; Shpiro NA; van Aalten DM
    J Am Chem Soc; 2006 Dec; 128(51):16484-5. PubMed ID: 17177381
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of NAM-thiazoline derivatives as novel O-GlcNAcase inhibitors.
    Kong H; Chen W; Liu T; Lu H; Yang Q; Dong Y; Liang X; Jin S; Zhang J
    Carbohydr Res; 2016 Jun; 429():54-61. PubMed ID: 27233493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors.
    Bergeron-Brlek M; Goodwin-Tindall J; Cekic N; Roth C; Zandberg WF; Shan X; Varghese V; Chan S; Davies GJ; Vocadlo DJ; Britton R
    Angew Chem Int Ed Engl; 2015 Dec; 54(51):15429-33. PubMed ID: 26545827
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.