258 related articles for article (PubMed ID: 30413706)
1. The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance.
Han F; Li CF; Cai Z; Zhang X; Jin G; Zhang WN; Xu C; Wang CY; Morrow J; Zhang S; Xu D; Wang G; Lin HK
Nat Commun; 2018 Nov; 9(1):4728. PubMed ID: 30413706
[TBL] [Abstract][Full Text] [Related]
2. The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.
Chan CH; Li CF; Yang WL; Gao Y; Lee SW; Feng Z; Huang HY; Tsai KK; Flores LG; Shao Y; Hazle JD; Yu D; Wei W; Sarbassov D; Hung MC; Nakayama KI; Lin HK
Cell; 2012 May; 149(5):1098-111. PubMed ID: 22632973
[TBL] [Abstract][Full Text] [Related]
3. Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser1177 via an AMPK mediated pathway independent of PI3K-Akt.
Thors B; Halldórsson H; Thorgeirsson G
FEBS Lett; 2004 Aug; 573(1-3):175-80. PubMed ID: 15327994
[TBL] [Abstract][Full Text] [Related]
4. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.
Lin HK; Wang G; Chen Z; Teruya-Feldstein J; Liu Y; Chan CH; Yang WL; Erdjument-Bromage H; Nakayama KI; Nimer S; Tempst P; Pandolfi PP
Nat Cell Biol; 2009 Apr; 11(4):420-32. PubMed ID: 19270694
[TBL] [Abstract][Full Text] [Related]
5. Skp2-mediated ubiquitination and mitochondrial localization of Akt drive tumor growth and chemoresistance to cisplatin.
Yu X; Wang R; Zhang Y; Zhou L; Wang W; Liu H; Li W
Oncogene; 2019 Dec; 38(50):7457-7472. PubMed ID: 31435020
[TBL] [Abstract][Full Text] [Related]
6. Fascaplysin Sensitizes Anti-Cancer Effects of Drugs Targeting AKT and AMPK.
Oh TI; Lee JH; Kim S; Nam TJ; Kim YS; Kim BM; Yim WJ; Lim JH
Molecules; 2017 Dec; 23(1):. PubMed ID: 29295560
[TBL] [Abstract][Full Text] [Related]
7. Xanthohumol Promotes Skp2 Ubiquitination Leading to the Inhibition of Glycolysis and Tumorigenesis in Ovarian Cancer.
He YF; Liu YP; Liao JZ; Gan Y; Li X; Wang RR; Wang F; Zhou J; Zhou L
Am J Chin Med; 2024; 52(3):865-884. PubMed ID: 38790085
[TBL] [Abstract][Full Text] [Related]
8. Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells.
Gan Y; Shi C; Inge L; Hibner M; Balducci J; Huang Y
Oncogene; 2010 Sep; 29(35):4947-58. PubMed ID: 20562913
[TBL] [Abstract][Full Text] [Related]
9. Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.
Clement E; Inuzuka H; Nihira NT; Wei W; Toker A
Sci Signal; 2018 Mar; 11(521):. PubMed ID: 29535262
[TBL] [Abstract][Full Text] [Related]
10. Calcium/calmodulin-dependent protein kinase kinase 2 mediates pleiotropic effects of epidermal growth factor in cancer cells.
Dai S; Venturini E; Yadav S; Lin X; Clapp D; Steckiewicz M; Gocher-Demske AM; Hardie DG; Edelman AM
Biochim Biophys Acta Mol Cell Res; 2022 Jul; 1869(7):119252. PubMed ID: 35271909
[TBL] [Abstract][Full Text] [Related]
11. MEK inhibitors induce Akt activation and drug resistance by suppressing negative feedback ERK-mediated HER2 phosphorylation at Thr701.
Chen CH; Hsia TC; Yeh MH; Chen TW; Chen YJ; Chen JT; Wei YL; Tu CY; Huang WC
Mol Oncol; 2017 Sep; 11(9):1273-1287. PubMed ID: 28632938
[TBL] [Abstract][Full Text] [Related]
12. Ferulic Acid Exerts Anti-Angiogenic and Anti-Tumor Activity by Targeting Fibroblast Growth Factor Receptor 1-Mediated Angiogenesis.
Yang GW; Jiang JS; Lu WQ
Int J Mol Sci; 2015 Oct; 16(10):24011-31. PubMed ID: 26473837
[TBL] [Abstract][Full Text] [Related]
13. SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis.
Wang G; Long J; Gao Y; Zhang W; Han F; Xu C; Sun L; Yang SC; Lan J; Hou Z; Cai Z; Jin G; Hsu CC; Wang YH; Hu J; Chen TY; Li H; Lee MG; Lin HK
Nat Cell Biol; 2019 Feb; 21(2):214-225. PubMed ID: 30692626
[TBL] [Abstract][Full Text] [Related]
14. Skp2: caught in the Akt.
Ecker K; Hengst L
Nat Cell Biol; 2009 Apr; 11(4):377-9. PubMed ID: 19337320
[TBL] [Abstract][Full Text] [Related]
15. Protein Kinases Type II (PKG II) Combined with L-Arginine Significantly Ameliorated Xenograft Tumor Development: Is L-Arginine a Potential Alternative in PKG II Activation?
Wu Y; Liu Y; Cai Z; Qin H; Li H; Su W; Wang Y; Qian H; Jiang L; Wu M; Pang J; Chen Y
Med Sci Monit; 2018 Feb; 24():736-742. PubMed ID: 29401205
[TBL] [Abstract][Full Text] [Related]
16. EGF‑stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib‑resistant human lung cancer cell line.
Nishimura Y; Takiguchi S; Ito S; Itoh K
Int J Oncol; 2015 Apr; 46(4):1721-9. PubMed ID: 25653196
[TBL] [Abstract][Full Text] [Related]
17. Epidermal Growth Factor Reverses the Inhibitory Effects of the Bisphosphonate, Zoledronic Acid, on Human Oral Keratinocytes and Human Vascular Endothelial Cells In Vitro via the Epidermal Growth Factor Receptor (EGFR)/Akt/Phosphoinositide 3-Kinase (PI3K) Signaling Pathway.
Wang Q; Liu J; Guo T; Liu D; Pan J
Med Sci Monit; 2019 Jan; 25():700-710. PubMed ID: 30675875
[TBL] [Abstract][Full Text] [Related]
18. Activation of AMPK α2 inhibits airway smooth muscle cells proliferation.
Liu L; Pan Y; Song Y; Su X; Ke R; Yang L; Gao L; Li M
Eur J Pharmacol; 2016 Nov; 791():235-243. PubMed ID: 27600020
[TBL] [Abstract][Full Text] [Related]
19. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
Hales EC; Taub JW; Matherly LH
Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
[TBL] [Abstract][Full Text] [Related]
20. Cdh1-mediated Skp2 degradation by dioscin reprogrammes aerobic glycolysis and inhibits colorectal cancer cells growth.
Zhou L; Yu X; Li M; Gong G; Liu W; Li T; Zuo H; Li W; Gao F; Liu H
EBioMedicine; 2020 Jan; 51():102570. PubMed ID: 31806563
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
