These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 30422705)

  • 1. Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues.
    Kulas JA; Franklin WF; Smith NA; Manocha GD; Puig KL; Nagamoto-Combs K; Hendrix RD; Taglialatela G; Barger SW; Combs CK
    Am J Physiol Endocrinol Metab; 2019 Jan; 316(1):E106-E120. PubMed ID: 30422705
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
    Farris W; Mansourian S; Chang Y; Lindsley L; Eckman EA; Frosch MP; Eckman CB; Tanzi RE; Selkoe DJ; Guenette S
    Proc Natl Acad Sci U S A; 2003 Apr; 100(7):4162-7. PubMed ID: 12634421
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High-fat diet induced discrepant peripheral and central nervous systems insulin resistance in APPswe/PS1dE9 and wild-type C57BL/6J mice.
    Guo Y; Ma X; Li P; Dong S; Huang X; Ren X; Yuan L
    Aging (Albany NY); 2020 Dec; 13(1):1236-1250. PubMed ID: 33291072
    [No Abstract]   [Full Text] [Related]  

  • 4. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.
    Rockenstein E; Torrance M; Mante M; Adame A; Paulino A; Rose JB; Crews L; Moessler H; Masliah E
    J Neurosci Res; 2006 May; 83(7):1252-61. PubMed ID: 16511867
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glucocorticoids facilitate astrocytic amyloid-β peptide deposition by increasing the expression of APP and BACE1 and decreasing the expression of amyloid-β-degrading proteases.
    Wang Y; Li M; Tang J; Song M; Xu X; Xiong J; Li J; Bai Y
    Endocrinology; 2011 Jul; 152(7):2704-15. PubMed ID: 21558319
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymoquinone-rich fraction nanoemulsion (TQRFNE) decreases Aβ40 and Aβ42 levels by modulating APP processing, up-regulating IDE and LRP1, and down-regulating BACE1 and RAGE in response to high fat/cholesterol diet-induced rats.
    Ismail N; Ismail M; Azmi NH; Bakar MFA; Yida Z; Abdullah MA; Basri H
    Biomed Pharmacother; 2017 Nov; 95():780-788. PubMed ID: 28892789
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of Global Brain Ischemia on Amyloid Precursor Protein Metabolism and Expression of Amyloid-Degrading Enzymes in Rat Cortex: Role in Pathogenesis of Alzheimer's Disease.
    Babusikova E; Dobrota D; Turner AJ; Nalivaeva NN
    Biochemistry (Mosc); 2021 Jun; 86(6):680-692. PubMed ID: 34225591
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Susceptibility to diet-induced obesity and glucose intolerance in the APP (SWE)/PSEN1 (A246E) mouse model of Alzheimer's disease is associated with increased brain levels of protein tyrosine phosphatase 1B (PTP1B) and retinol-binding protein 4 (RBP4), and basal phosphorylation of S6 ribosomal protein.
    Mody N; Agouni A; McIlroy GD; Platt B; Delibegovic M
    Diabetologia; 2011 Aug; 54(8):2143-51. PubMed ID: 21538175
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of Fasting and Feeding on Transcriptional and Posttranscriptional Regulation of Insulin-Degrading Enzyme in Mice.
    González-Casimiro CM; Cámara-Torres P; Merino B; Diez-Hermano S; Postigo-Casado T; Leissring MA; Cózar-Castellano I; Perdomo G
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572095
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Examining the effects of ovarian hormone loss and diet-induced obesity on Alzheimer's disease markers of amyloid-β production and degradation.
    Hayward GC; Baranowski BJ; Marko DM; MacPherson REK
    J Neurophysiol; 2021 Apr; 125(4):1068-1078. PubMed ID: 33534663
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulatory feedback cycle of the insulin-degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer's disease.
    Lauer AA; Mett J; Janitschke D; Thiel A; Stahlmann CP; Bachmann CM; Ritzmann F; Schrul B; Müller UC; Stein R; Riemenschneider M; Grimm HS; Hartmann T; Grimm MOW
    Aging Cell; 2020 Nov; 19(11):e13264. PubMed ID: 33128835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.
    Farris W; Leissring MA; Hemming ML; Chang AY; Selkoe DJ
    Biochemistry; 2005 May; 44(17):6513-25. PubMed ID: 15850385
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Aβ metabolism.
    Leal MC; Surace EI; Holgado MP; Ferrari CC; Tarelli R; Pitossi F; Wisniewski T; Castaño EM; Morelli L
    Biochim Biophys Acta; 2012 Feb; 1823(2):227-35. PubMed ID: 22036964
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology.
    Zhao Z; Ho L; Wang J; Qin W; Festa ED; Mobbs C; Hof P; Rocher A; Masur S; Haroutunian V; Pasinetti GM
    FASEB J; 2005 Dec; 19(14):2081-2. PubMed ID: 16186174
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitory Effect of Memantine on Streptozotocin-Induced Insulin Receptor Dysfunction, Neuroinflammation, Amyloidogenesis, and Neurotrophic Factor Decline in Astrocytes.
    Rajasekar N; Nath C; Hanif K; Shukla R
    Mol Neurobiol; 2016 Dec; 53(10):6730-6744. PubMed ID: 26660109
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Effects of Peripheral and Central High Insulin on Brain Insulin Signaling and Amyloid-β in Young and Old APP/PS1 Mice.
    Stanley M; Macauley SL; Caesar EE; Koscal LJ; Moritz W; Robinson GO; Roh J; Keyser J; Jiang H; Holtzman DM
    J Neurosci; 2016 Nov; 36(46):11704-11715. PubMed ID: 27852778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reduced insulin clearance and lower insulin-degrading enzyme expression in the liver might contribute to the thrifty phenotype of protein-restricted mice.
    Rezende LF; Camargo RL; Branco RC; Cappelli AP; Boschero AC; Carneiro EM
    Br J Nutr; 2014 Sep; 112(6):900-7. PubMed ID: 25036874
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.
    Tian J; Shi J; Zhang L; Yin J; Hu Q; Xu Y; Sheng S; Wang P; Ren Y; Wang R; Wang Y
    Curr Alzheimer Res; 2009 Apr; 6(2):118-31. PubMed ID: 19355846
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impaired performance of female APP/PS1 mice in the Morris water maze is coupled with increased Aβ accumulation and microglial activation.
    Gallagher JJ; Minogue AM; Lynch MA
    Neurodegener Dis; 2013; 11(1):33-41. PubMed ID: 22627185
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New Insights into Epigenetic and Pharmacological Regulation of Amyloid-Degrading Enzymes.
    Nalivaeva NN; Belyaev ND; Turner AJ
    Neurochem Res; 2016 Mar; 41(3):620-30. PubMed ID: 26376806
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.