BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 30429313)

  • 1. Site occupancy calibration of taxane pharmacology in live cells and tissues.
    Pineda JJ; Miller MA; Song Y; Kuhn H; Mikula H; Tallapragada N; Weissleder R; Mitchison TJ
    Proc Natl Acad Sci U S A; 2018 Nov; 115(48):E11406-E11414. PubMed ID: 30429313
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 3D QSAR models of interactions between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA): a survey on taxanes and epothilones.
    Manetti F; Maccari L; Corelli F; Botta M
    Curr Top Med Chem; 2004; 4(2):203-17. PubMed ID: 14754454
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular mechanism of action of microtubule-stabilizing anticancer agents.
    Prota AE; Bargsten K; Zurwerra D; Field JJ; Díaz JF; Altmann KH; Steinmetz MO
    Science; 2013 Feb; 339(6119):587-90. PubMed ID: 23287720
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
    Matesanz R; Trigili C; Rodríguez-Salarichs J; Zanardi I; Pera B; Nogales A; Fang WS; Jímenez-Barbero J; Canales A; Barasoain I; Ojima I; Díaz JF
    Bioorg Med Chem; 2014 Sep; 22(18):5078-90. PubMed ID: 25047938
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of C7 substitutions in a high affinity microtubule-binding taxane on antitumor activity and drug transport.
    Xiao X; Wu J; Trigili C; Chen H; Chu JW; Zhao Y; Lu P; Sheng L; Li Y; Sharom FJ; Barasoain I; Diaz JF; Fang WS
    Bioorg Med Chem Lett; 2011 Aug; 21(16):4852-6. PubMed ID: 21764308
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
    Field JJ; Pera B; Calvo E; Canales A; Zurwerra D; Trigili C; Rodríguez-Salarichs J; Matesanz R; Kanakkanthara A; Wakefield SJ; Singh AJ; Jiménez-Barbero J; Northcote P; Miller JH; López JA; Hamel E; Barasoain I; Altmann KH; Díaz JF
    Chem Biol; 2012 Jun; 19(6):686-98. PubMed ID: 22726683
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Microtubule-binding natural products for cancer therapy.
    Yue QX; Liu X; Guo DA
    Planta Med; 2010 Aug; 76(11):1037-43. PubMed ID: 20577942
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site.
    Lo YC; Cormier O; Liu T; Nettles KW; Katzenellenbogen JA; Stearns T; Altman RB
    Nat Commun; 2019 Mar; 10(1):1033. PubMed ID: 30833575
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
    Hidaka M; Koga T; Kiyota H; Horiguchi T; Shi QW; Hirose K; Uchida T
    Biosci Biotechnol Biochem; 2012; 76(2):349-52. PubMed ID: 22313785
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CCR 20th anniversary commentary: BMS-247550—microtubule stabilization as successful targeted therapy.
    Pabla N; Sparreboom A
    Clin Cancer Res; 2015 Mar; 21(6):1237-9. PubMed ID: 25770292
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of novel epothilone analogues by means of a common pharmacophore and a QSAR pseudoreceptor model for taxanes and epothilones.
    Forli S; Manetti F; Altmann KH; Botta M
    ChemMedChem; 2010 Jan; 5(1):35-40. PubMed ID: 19904799
    [No Abstract]   [Full Text] [Related]  

  • 12. 3D QSAR studies of the interaction between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA). A combined pharmacophore generation and pseudoreceptor modeling approach applied to taxanes and epothilones.
    Manetti F; Forli S; Maccari L; Corelli F; Botta M
    Farmaco; 2003 May; 58(5):357-61. PubMed ID: 12729829
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents.
    Wang RC; Chen X; Parissenti AM; Joy AA; Tuszynski J; Brindley DN; Wang Z
    PLoS One; 2017; 12(8):e0182400. PubMed ID: 28787019
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular dynamics and tubulin polymerization kinetics study on 1,14-heterofused taxanes: evidence of stabilization of the tubulin head-to-tail dimer-dimer interaction.
    Contini A; Cappelletti G; Cartelli D; Fontana G; Gelmi ML
    Mol Biosyst; 2012 Oct; 8(12):3254-61. PubMed ID: 23073462
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclostreptin and microtubules: is a low-affinity binding site required?
    Prussia AJ; Yang Y; Geballe MT; Snyder JP
    Chembiochem; 2010 Jan; 11(1):101-9. PubMed ID: 19946930
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest.
    Kamath K; Jordan MA
    Cancer Res; 2003 Sep; 63(18):6026-31. PubMed ID: 14522931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanical aspects of microtubule bundling in taxane-treated circulating tumor cells.
    Kim M; Rejniak KA
    Biophys J; 2014 Sep; 107(5):1236-1246. PubMed ID: 25185559
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel.
    Matesanz R; Barasoain I; Yang CG; Wang L; Li X; de Inés C; Coderch C; Gago F; Barbero JJ; Andreu JM; Fang WS; Díaz JF
    Chem Biol; 2008 Jun; 15(6):573-85. PubMed ID: 18559268
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of other microtubule-stabilizer families: the epothilones and their derivatives.
    Brogdon CF; Lee FY; Canetta RM
    Anticancer Drugs; 2014 May; 25(5):599-609. PubMed ID: 24398663
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Understanding tubulin/microtubule-taxane interactions: a quantitative structure-activity relationship study.
    Hansch C; Verma RP
    Mol Pharm; 2008; 5(1):151-61. PubMed ID: 18171015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.