BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 30429376)

  • 21. Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures.
    Haynes P; Kernan K; Zhou SL; Miller DG
    Skelet Muscle; 2017 Jun; 7(1):13. PubMed ID: 28637492
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Aberrant splicing in transgenes containing introns, exons, and V5 epitopes: lessons from developing an FSHD mouse model expressing a D4Z4 repeat with flanking genomic sequences.
    Ansseau E; Domire JS; Wallace LM; Eidahl JO; Guckes SM; Giesige CR; Pyne NK; Belayew A; Harper SQ
    PLoS One; 2015; 10(3):e0118813. PubMed ID: 25742305
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Human miRNA miR-675 inhibits DUX4 expression and may be exploited as a potential treatment for Facioscapulohumeral muscular dystrophy.
    Saad NY; Al-Kharsan M; Garwick-Coppens SE; Chermahini GA; Harper MA; Palo A; Boudreau RL; Harper SQ
    Nat Commun; 2021 Dec; 12(1):7128. PubMed ID: 34880230
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Sporadic DUX4 expression in FSHD myocytes is associated with incomplete repression by the PRC2 complex and gain of H3K9 acetylation on the contracted D4Z4 allele.
    Haynes P; Bomsztyk K; Miller DG
    Epigenetics Chromatin; 2018 Aug; 11(1):47. PubMed ID: 30122154
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Transgenic zebrafish model of DUX4 misexpression reveals a developmental role in FSHD pathogenesis.
    Pakula A; Lek A; Widrick J; Mitsuhashi H; Bugda Gwilt KM; Gupta VA; Rahimov F; Criscione J; Zhang Y; Gibbs D; Murphy Q; Manglik A; Mead L; Kunkel L
    Hum Mol Genet; 2019 Jan; 28(2):320-331. PubMed ID: 30307508
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Myostatin inhibition by a follistatin-derived peptide ameliorates the pathophysiology of muscular dystrophy model mice.
    Tsuchida K
    Acta Myol; 2008 Jul; 27(1):14-8. PubMed ID: 19108572
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Muscle xenografts reproduce key molecular features of facioscapulohumeral muscular dystrophy.
    Mueller AL; O'Neill A; Jones TI; Llach A; Rojas LA; Sakellariou P; Stadler G; Wright WE; Eyerman D; Jones PL; Bloch RJ
    Exp Neurol; 2019 Oct; 320():113011. PubMed ID: 31306642
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Single-cell RNA sequencing in facioscapulohumeral muscular dystrophy disease etiology and development.
    van den Heuvel A; Mahfouz A; Kloet SL; Balog J; van Engelen BGM; Tawil R; Tapscott SJ; van der Maarel SM
    Hum Mol Genet; 2019 Apr; 28(7):1064-1075. PubMed ID: 30445587
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Overexpression of the double homeodomain protein DUX4c interferes with myofibrillogenesis and induces clustering of myonuclei.
    Vanderplanck C; Tassin A; Ansseau E; Charron S; Wauters A; Lancelot C; Vancutsem K; Laoudj-Chenivesse D; Belayew A; Coppée F
    Skelet Muscle; 2018 Jan; 8(1):2. PubMed ID: 29329560
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy.
    Lek A; Zhang Y; Woodman KG; Huang S; DeSimone AM; Cohen J; Ho V; Conner J; Mead L; Kodani A; Pakula A; Sanjana N; King OD; Jones PL; Wagner KR; Lek M; Kunkel LM
    Sci Transl Med; 2020 Mar; 12(536):. PubMed ID: 32213627
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy.
    Feng Q; Snider L; Jagannathan S; Tawil R; van der Maarel SM; Tapscott SJ; Bradley RK
    Elife; 2015 Jan; 4():. PubMed ID: 25564732
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Dominant lethal pathologies in male mice engineered to contain an X-linked DUX4 transgene.
    Dandapat A; Bosnakovski D; Hartweck LM; Arpke RW; Baltgalvis KA; Vang D; Baik J; Darabi R; Perlingeiro RC; Hamra FK; Gupta K; Lowe DA; Kyba M
    Cell Rep; 2014 Sep; 8(5):1484-96. PubMed ID: 25176645
    [TBL] [Abstract][Full Text] [Related]  

  • 33. PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle.
    Banerji CRS; Panamarova M; Hebaishi H; White RB; Relaix F; Severini S; Zammit PS
    Nat Commun; 2017 Dec; 8(1):2152. PubMed ID: 29255294
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells.
    Jagannathan S; Shadle SC; Resnick R; Snider L; Tawil RN; van der Maarel SM; Bradley RK; Tapscott SJ
    Hum Mol Genet; 2016 Oct; 25(20):4419-4431. PubMed ID: 28171552
    [TBL] [Abstract][Full Text] [Related]  

  • 35. DUX4 expressing immortalized FSHD lymphoblastoid cells express genes elevated in FSHD muscle biopsies, correlating with the early stages of inflammation.
    Banerji CRS; Panamarova M; Zammit PS
    Hum Mol Genet; 2020 Aug; 29(14):2285-2299. PubMed ID: 32242220
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Knocking Down DUX4 in Immortalized Facioscapulohumeral Muscular Dystrophy Patient-Derived Muscle Cells.
    Lim KRQ; Yokota T
    Methods Mol Biol; 2023; 2587():197-208. PubMed ID: 36401032
    [TBL] [Abstract][Full Text] [Related]  

  • 37. MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD.
    Wang LH; Friedman SD; Shaw D; Snider L; Wong CJ; Budech CB; Poliachik SL; Gove NE; Lewis LM; Campbell AE; Lemmers RJFL; Maarel SM; Tapscott SJ; Tawil RN
    Hum Mol Genet; 2019 Feb; 28(3):476-486. PubMed ID: 30312408
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease.
    Rodino-Klapac LR; Haidet AM; Kota J; Handy C; Kaspar BK; Mendell JR
    Muscle Nerve; 2009 Mar; 39(3):283-96. PubMed ID: 19208403
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Facioscapulohumeral muscular dystrophy.
    Tawil R
    Handb Clin Neurol; 2018; 148():541-548. PubMed ID: 29478599
    [TBL] [Abstract][Full Text] [Related]  

  • 40. β-Catenin is central to DUX4-driven network rewiring in facioscapulohumeral muscular dystrophy.
    Banerji CR; Knopp P; Moyle LA; Severini S; Orrell RW; Teschendorff AE; Zammit PS
    J R Soc Interface; 2015 Jan; 12(102):20140797. PubMed ID: 25551153
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.