130 related articles for article (PubMed ID: 30439482)
1. Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome.
Silva J; Chang CS; Hu T; Qin H; Kitamura E; Hawthorn L; Ren M; Cowell JK
Genomics; 2019 Dec; 111(6):1566-1573. PubMed ID: 30439482
[TBL] [Abstract][Full Text] [Related]
2. A truncated derivative of FGFR1 kinase cooperates with FLT3 and KIT to transform hematopoietic stem cells in syndromic and de novo AML.
Cai B; Liu Y; Chong Y; Mori SF; Matsunaga A; Zhang H; Fang X; Chang CS; Cowell JK; Hu T
Mol Cancer; 2022 Jul; 21(1):156. PubMed ID: 35906694
[TBL] [Abstract][Full Text] [Related]
3. IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies.
Cai B; Liu Y; Chong Y; Zhang H; Matsunaga A; Fang X; Pacholczyk R; Zhou G; Cowell JK; Hu T
Mol Cancer; 2021 Dec; 20(1):165. PubMed ID: 34906138
[TBL] [Abstract][Full Text] [Related]
4. Development of ZMYM2-FGFR1 driven AML in human CD34+ cells in immunocompromised mice.
Ren M; Qin H; Wu Q; Savage NM; George TI; Cowell JK
Int J Cancer; 2016 Aug; 139(4):836-40. PubMed ID: 27005999
[TBL] [Abstract][Full Text] [Related]
5. Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome.
Chong Y; Liu Y; Lu S; Cai B; Qin H; Chang CS; Ren M; Cowell JK; Hu T
Int J Cancer; 2020 Apr; 146(8):2243-2254. PubMed ID: 31525277
[TBL] [Abstract][Full Text] [Related]
6. miR-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the
Hu T; Chong Y; Lu S; Wang R; Qin H; Silva J; Kitamura E; Chang CS; Hawthorn L; Cowell JK
Cancer Res; 2018 Jul; 78(13):3522-3531. PubMed ID: 29735550
[TBL] [Abstract][Full Text] [Related]
7. Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases.
Ren M; Qin H; Ren R; Tidwell J; Cowell JK
Cancer Res; 2011 Dec; 71(23):7312-22. PubMed ID: 21937681
[TBL] [Abstract][Full Text] [Related]
8. Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance.
Ly M; Rentas S; Vujovic A; Wong N; Moreira S; Xu J; Holzapfel N; Bhatia S; Tran D; Minden MD; Draper JS; Hope KJ
Cancer Res; 2019 Nov; 79(22):5799-5811. PubMed ID: 31519687
[TBL] [Abstract][Full Text] [Related]
9. Determination of P-glycoprotein, MDR-related protein 1, breast cancer resistance protein, and lung-resistance protein expression in leukemic stem cells of acute myeloid leukemia.
de Figueiredo-Pontes LL; Pintão MC; Oliveira LC; Dalmazzo LF; Jácomo RH; Garcia AB; Falcão RP; Rego EM
Cytometry B Clin Cytom; 2008 May; 74(3):163-8. PubMed ID: 18200595
[TBL] [Abstract][Full Text] [Related]
10. Mutation in the FGFR1 tyrosine kinase domain or inactivation of PTEN is associated with acquired resistance to FGFR inhibitors in FGFR1-driven leukemia/lymphomas.
Cowell JK; Qin H; Hu T; Wu Q; Bhole A; Ren M
Int J Cancer; 2017 Nov; 141(9):1822-1829. PubMed ID: 28646488
[TBL] [Abstract][Full Text] [Related]
11. Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice.
Hu T; Chong Y; Lu S; Qin H; Ren M; Savage NM; Chang CS; Cowell JK
Cancer Res; 2019 Jan; 79(1):114-124. PubMed ID: 30413411
[TBL] [Abstract][Full Text] [Related]
12. Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.
Ren M; Cowell JK
Blood; 2011 Jun; 117(25):6837-47. PubMed ID: 21527531
[TBL] [Abstract][Full Text] [Related]
13. Differential niche and Wnt requirements during acute myeloid leukemia progression.
Lane SW; Wang YJ; Lo Celso C; Ragu C; Bullinger L; Sykes SM; Ferraro F; Shterental S; Lin CP; Gilliland DG; Scadden DT; Armstrong SA; Williams DA
Blood; 2011 Sep; 118(10):2849-56. PubMed ID: 21765021
[TBL] [Abstract][Full Text] [Related]
14. Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models.
Ren M; Qin H; Kitamura E; Cowell JK
Blood; 2013 Aug; 122(6):1007-16. PubMed ID: 23777766
[TBL] [Abstract][Full Text] [Related]
15. Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.
Diffner E; Beck D; Gudgin E; Thoms JA; Knezevic K; Pridans C; Foster S; Goode D; Lim WK; Boelen L; Metzeler KH; Micklem G; Bohlander SK; Buske C; Burnett A; Ottersbach K; Vassiliou GS; Olivier J; Wong JW; Göttgens B; Huntly BJ; Pimanda JE
Blood; 2013 Mar; 121(12):2289-300. PubMed ID: 23327922
[TBL] [Abstract][Full Text] [Related]
16. Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells.
Cook AM; Li L; Ho Y; Lin A; Li L; Stein A; Forman S; Perrotti D; Jove R; Bhatia R
Blood; 2014 May; 123(18):2826-37. PubMed ID: 24668492
[TBL] [Abstract][Full Text] [Related]
17. Constitutive activation of Flt3 and STAT5A enhances self-renewal and alters differentiation of hematopoietic stem cells.
Moore MA; Dorn DC; Schuringa JJ; Chung KY; Morrone G
Exp Hematol; 2007 Apr; 35(4 Suppl 1):105-16. PubMed ID: 17379095
[TBL] [Abstract][Full Text] [Related]
18. A model of BCR-FGFR1 driven human AML in immunocompromised mice.
Cowell JK; Qin H; Chang CS; Kitamura E; Ren M
Br J Haematol; 2016 Nov; 175(3):542-545. PubMed ID: 27785808
[No Abstract] [Full Text] [Related]
19. GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis.
Dietrich PA; Yang C; Leung HH; Lynch JR; Gonzales E; Liu B; Haber M; Norris MD; Wang J; Wang JY
Blood; 2014 Nov; 124(22):3284-94. PubMed ID: 25293777
[TBL] [Abstract][Full Text] [Related]
20. Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia.
Sachs K; Sarver AL; Noble-Orcutt KE; LaRue RS; Antony ML; Chang D; Lee Y; Navis CM; Hillesheim AL; Nykaza IR; Ha NA; Hansen CJ; Karadag FK; Bergerson RJ; Verneris MR; Meredith MM; Schomaker ML; Linden MA; Myers CL; Largaespada DA; Sachs Z
Cancer Res; 2020 Feb; 80(3):458-470. PubMed ID: 31784425
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
