These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 30442673)

  • 1. Efavirenz and Efavirenz-like Compounds Activate Human, Murine, and Macaque Hepatic IRE1
    Heck CJS; Hamlin AN; Bumpus NN
    Mol Pharmacol; 2019 Feb; 95(2):183-195. PubMed ID: 30442673
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
    Liu X; Guo GL; Kong B; Hilburn DB; Hubchak SC; Park S; LeCuyer B; Hsieh A; Wang L; Fang D; Green RM
    Hepatology; 2018 Jul; 68(1):304-316. PubMed ID: 29377207
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic program.
    Ning J; Hong T; Ward A; Pi J; Liu Z; Liu HY; Cao W
    Endocrinology; 2011 Jun; 152(6):2247-55. PubMed ID: 21447637
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α.
    Duwaerts CC; Siao K; Soon RK; Her C; Iwawaki T; Kohno K; Mattis AN; Maher JJ
    Cell Death Differ; 2021 May; 28(5):1455-1465. PubMed ID: 33219328
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KIRA8 attenuates non-alcoholic steatohepatitis through inhibition of the IRE1α/XBP1 signalling pathway.
    Zhao S; Liu X; Li L; Kong X; Sun W; Loomes K; Nie T; Hui X; Wu D
    Biochem Biophys Res Commun; 2022 Dec; 632():158-164. PubMed ID: 36209584
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Efavirenz and 8-hydroxyefavirenz induce cell death via a JNK- and BimEL-dependent mechanism in primary human hepatocytes.
    Bumpus NN
    Toxicol Appl Pharmacol; 2011 Dec; 257(2):227-34. PubMed ID: 21958719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probing Ligand Structure-Activity Relationships in Pregnane X Receptor (PXR): Efavirenz and 8-Hydroxyefavirenz Exhibit Divergence in Activation.
    Narayanan B; Lade JM; Heck CJS; Dietz KD; Wade H; Bumpus NN
    ChemMedChem; 2018 Apr; 13(7):736-747. PubMed ID: 29430850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression.
    Qi Y; Wang W; Chen J; Dai L; Kaczorowski D; Gao X; Xia P
    J Biol Chem; 2015 Sep; 290(38):23282-90. PubMed ID: 26240153
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
    Blazanin N; Son J; Craig-Lucas AB; John CL; Breech KJ; Podolsky MA; Glick AB
    Proc Natl Acad Sci U S A; 2017 Sep; 114(37):9900-9905. PubMed ID: 28847931
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhanced IRE1α Phosphorylation/Oligomerization-Triggered XBP1 Splicing Contributes to Parkin-Mediated Prevention of SH-SY5Y Cell Death under Nitrosative Stress.
    Chiu TL; Huang HY; Chang HF; Wu HR; Wang MJ
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768338
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway.
    Tsuru A; Imai Y; Saito M; Kohno K
    Sci Rep; 2016 Apr; 6():24217. PubMed ID: 27052593
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toll-like receptor 2 (TLR2) engages endoplasmic reticulum stress sensor IRE1α to regulate retinal innate responses in Staphylococcus aureus endophthalmitis.
    Kumar A; Singh PK; Zhang K; Kumar A
    FASEB J; 2020 Oct; 34(10):13826-13838. PubMed ID: 32813318
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylation at Ser
    Li Y; Huang S; Wang J; Dai J; Cai J; Yan S; Huang Z; He S; Wang P; Liu J; Liu Y
    J Biol Chem; 2022 Jun; 298(6):101997. PubMed ID: 35500653
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.
    Jiang D; Lynch C; Medeiros BC; Liedtke M; Bam R; Tam AB; Yang Z; Alagappan M; Abidi P; Le QT; Giaccia AJ; Denko NC; Niwa M; Koong AC
    Sci Rep; 2016 Sep; 6():33353. PubMed ID: 27634301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
    Chen C; Zhang X
    J Transl Med; 2017 Feb; 15(1):42. PubMed ID: 28222747
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice.
    Lebeaupin C; Vallée D; Rousseau D; Patouraux S; Bonnafous S; Adam G; Luciano F; Luci C; Anty R; Iannelli A; Marchetti S; Kroemer G; Lacas-Gervais S; Tran A; Gual P; Bailly-Maitre B
    Hepatology; 2018 Aug; 68(2):515-532. PubMed ID: 29457838
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.
    Chopra S; Giovanelli P; Alvarado-Vazquez PA; Alonso S; Song M; Sandoval TA; Chae CS; Tan C; Fonseca MM; Gutierrez S; Jimenez L; Subbaramaiah K; Iwawaki T; Kingsley PJ; Marnett LJ; Kossenkov AV; Crespo MS; Dannenberg AJ; Glimcher LH; Romero-Sandoval EA; Cubillos-Ruiz JR
    Science; 2019 Jul; 365(6450):. PubMed ID: 31320508
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.
    Hassler JR; Scheuner DL; Wang S; Han J; Kodali VK; Li P; Nguyen J; George JS; Davis C; Wu SP; Bai Y; Sartor M; Cavalcoli J; Malhi H; Baudouin G; Zhang Y; Yates JR; Itkin-Ansari P; Volkmann N; Kaufman RJ
    PLoS Biol; 2015 Oct; 13(10):e1002277. PubMed ID: 26469762
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.
    Jiang D; Tam AB; Alagappan M; Hay MP; Gupta A; Kozak MM; Solow-Cordero DE; Lum PY; Denko NC; Giaccia AJ; Le QT; Niwa M; Koong AC
    Mol Cancer Ther; 2016 Sep; 15(9):2055-65. PubMed ID: 27307600
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selenoprotein S regulates adipogenesis through IRE1α-XBP1 pathway.
    Men L; Yao J; Yu S; Li Y; Cui S; Jin S; Zhang G; Ren D; Du J
    J Endocrinol; 2020 Mar; 244(3):431-443. PubMed ID: 31846435
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.