310 related articles for article (PubMed ID: 30442762)
1. Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.
Steklov M; Pandolfi S; Baietti MF; Batiuk A; Carai P; Najm P; Zhang M; Jang H; Renzi F; Cai Y; Abbasi Asbagh L; Pastor T; De Troyer M; Simicek M; Radaelli E; Brems H; Legius E; Tavernier J; Gevaert K; Impens F; Messiaen L; Nussinov R; Heymans S; Eyckerman S; Sablina AA
Science; 2018 Dec; 362(6419):1177-1182. PubMed ID: 30442762
[TBL] [Abstract][Full Text] [Related]
2. Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling.
Motta M; Fidan M; Bellacchio E; Pantaleoni F; Schneider-Heieck K; Coppola S; Borck G; Salviati L; Zenker M; Cirstea IC; Tartaglia M
Hum Mol Genet; 2019 Mar; 28(6):1007-1022. PubMed ID: 30481304
[TBL] [Abstract][Full Text] [Related]
3. LZTR1 facilitates polyubiquitination and degradation of RAS-GTPases.
Abe T; Umeki I; Kanno SI; Inoue SI; Niihori T; Aoki Y
Cell Death Differ; 2020 Mar; 27(3):1023-1035. PubMed ID: 31337872
[TBL] [Abstract][Full Text] [Related]
4. The Noonan Syndrome Gene
Sewduth RN; Pandolfi S; Steklov M; Sheryazdanova A; Zhao P; Criem N; Baietti MF; Lechat B; Quarck R; Impens F; Sablina AA
Circ Res; 2020 May; 126(10):1379-1393. PubMed ID: 32175818
[TBL] [Abstract][Full Text] [Related]
5. RIT1 oncoproteins escape LZTR1-mediated proteolysis.
Castel P; Cheng A; Cuevas-Navarro A; Everman DB; Papageorge AG; Simanshu DK; Tankka A; Galeas J; Urisman A; McCormick F
Science; 2019 Mar; 363(6432):1226-1230. PubMed ID: 30872527
[TBL] [Abstract][Full Text] [Related]
6. Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs.
Cuevas-Navarro A; Rodriguez-Muñoz L; Grego-Bessa J; Cheng A; Rauen KA; Urisman A; McCormick F; Jimenez G; Castel P
Elife; 2022 Apr; 11():. PubMed ID: 35467524
[TBL] [Abstract][Full Text] [Related]
7. LZTR1: A promising adaptor of the CUL3 family.
Zhang H; Cao X; Wang J; Li Q; Zhao Y; Jin X
Oncol Lett; 2021 Jul; 22(1):564. PubMed ID: 34113392
[TBL] [Abstract][Full Text] [Related]
8. LZTR1 is a regulator of RAS ubiquitination and signaling.
Bigenzahn JW; Collu GM; Kartnig F; Pieraks M; Vladimer GI; Heinz LX; Sedlyarov V; Schischlik F; Fauster A; Rebsamen M; Parapatics K; Blomen VA; Müller AC; Winter GE; Kralovics R; Brummelkamp TR; Mlodzik M; Superti-Furga G
Science; 2018 Dec; 362(6419):1171-1177. PubMed ID: 30442766
[TBL] [Abstract][Full Text] [Related]
9. Rare variants in SOS2 and LZTR1 are associated with Noonan syndrome.
Yamamoto GL; Aguena M; Gos M; Hung C; Pilch J; Fahiminiya S; Abramowicz A; Cristian I; Buscarilli M; Naslavsky MS; Malaquias AC; Zatz M; Bodamer O; Majewski J; Jorge AA; Pereira AC; Kim CA; Passos-Bueno MR; Bertola DR
J Med Genet; 2015 Jun; 52(6):413-21. PubMed ID: 25795793
[TBL] [Abstract][Full Text] [Related]
10. Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Chen S; Vedula RS; Cuevas-Navarro A; Lu B; Hogg SJ; Wang E; Benbarche S; Knorr K; Kim WJ; Stanley RF; Cho H; Erickson C; Singer M; Cui D; Tittley S; Durham BH; Pavletich TS; Fiala E; Walsh MF; Inoue D; Monette S; Taylor J; Rosen N; McCormick F; Lindsley RC; Castel P; Abdel-Wahab O
Cancer Discov; 2022 Oct; 12(10):2434-2453. PubMed ID: 35904492
[TBL] [Abstract][Full Text] [Related]
11. Noonan syndrome-associated biallelic LZTR1 mutations cause cardiac hypertrophy and vascular malformations in zebrafish.
Nakagama Y; Takeda N; Ogawa S; Takeda H; Furutani Y; Nakanishi T; Sato T; Hirata Y; Oka A; Inuzuka R
Mol Genet Genomic Med; 2020 Mar; 8(3):e1107. PubMed ID: 31883238
[TBL] [Abstract][Full Text] [Related]
12. LZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion.
Abe T; Kanno SI; Niihori T; Terao M; Takada S; Aoki Y
Cell Death Dis; 2023 Aug; 14(8):556. PubMed ID: 37626065
[TBL] [Abstract][Full Text] [Related]
13. Delineation of LZTR1 mutation-positive patients with Noonan syndrome and identification of LZTR1 binding to RAF1-PPP1CB complexes.
Umeki I; Niihori T; Abe T; Kanno SI; Okamoto N; Mizuno S; Kurosawa K; Nagasaki K; Yoshida M; Ohashi H; Inoue SI; Matsubara Y; Fujiwara I; Kure S; Aoki Y
Hum Genet; 2019 Jan; 138(1):21-35. PubMed ID: 30368668
[TBL] [Abstract][Full Text] [Related]
14. The GSK3 kinase and LZTR1 protein regulate the stability of Ras family proteins and the proliferation of pancreatic cancer cells.
Palanivel C; Chaudhary N; Seshacharyulu P; Cox JL; Yan Y; Batra SK; Ouellette MM
Neoplasia; 2022 Mar; 25():28-40. PubMed ID: 35114566
[TBL] [Abstract][Full Text] [Related]
15. Delineation of dominant and recessive forms of LZTR1-associated Noonan syndrome.
Pagnamenta AT; Kaisaki PJ; Bennett F; Burkitt-Wright E; Martin HC; Ferla MP; Taylor JM; Gompertz L; Lahiri N; Tatton-Brown K; Newbury-Ecob R; Henderson A; Joss S; Weber A; Carmichael J; Turnpenny PD; McKee S; Forzano F; Ashraf T; Bradbury K; Shears D; Kini U; de Burca A; ; Blair E; Taylor JC; Stewart H
Clin Genet; 2019 Jun; 95(6):693-703. PubMed ID: 30859559
[TBL] [Abstract][Full Text] [Related]
16. LZTR1: Genotype Expansion in Noonan Syndrome.
Güemes M; Martín-Rivada Á; Ortiz-Cabrera NV; Martos-Moreno GÁ; Pozo-Román J; Argente J
Horm Res Paediatr; 2019; 92(4):269-275. PubMed ID: 31533111
[TBL] [Abstract][Full Text] [Related]
17. Cullin 3 and Its Role in Tumorigenesis.
Chen RH
Adv Exp Med Biol; 2020; 1217():187-210. PubMed ID: 31898229
[TBL] [Abstract][Full Text] [Related]
18. Oligo-astrocytoma in LZTR1-related Noonan syndrome.
Jacquinet A; Bonnard A; Capri Y; Martin D; Sadzot B; Bianchi E; Servais L; Sacré JP; Cavé H; Verloes A
Eur J Med Genet; 2020 Jan; 63(1):103617. PubMed ID: 30664951
[TBL] [Abstract][Full Text] [Related]
19. Providing more evidence on LZTR1 variants in Noonan syndrome patients.
Chinton J; Huckstadt V; Mucciolo M; Lepri F; Novelli A; Gravina LP; Obregon MG
Am J Med Genet A; 2020 Feb; 182(2):409-414. PubMed ID: 31825158
[TBL] [Abstract][Full Text] [Related]
20. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
Furukawa M; Xiong Y
Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
