318 related articles for article (PubMed ID: 30447259)
1. Role of extracellular vesicles in release of protein adducts after acetaminophen-induced liver injury in mice and humans.
Duan L; Ramachandran A; Akakpo JY; Weemhoff JL; Curry SC; Jaeschke H
Toxicol Lett; 2019 Feb; 301():125-132. PubMed ID: 30447259
[TBL] [Abstract][Full Text] [Related]
2. Time course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients and in HepaRG cells.
Xie Y; McGill MR; Cook SF; Sharpe MR; Winefield RD; Wilkins DG; Rollins DE; Jaeschke H
Xenobiotica; 2015; 45(10):921-9. PubMed ID: 25869248
[TBL] [Abstract][Full Text] [Related]
3. Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury.
Wang H; Burke LJ; Patel J; Tse BW; Bridle KR; Cogger VC; Li X; Liu X; Yang H; Crawford DHG; Roberts MS; Gao W; Liang X
Theranostics; 2020; 10(15):6715-6727. PubMed ID: 32550899
[TBL] [Abstract][Full Text] [Related]
4. Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.
Bhushan B; Chavan H; Borude P; Xie Y; Du K; McGill MR; Lebofsky M; Jaeschke H; Krishnamurthy P; Apte U
Toxicol Sci; 2017 Feb; 155(2):363-378. PubMed ID: 28123000
[TBL] [Abstract][Full Text] [Related]
5. Impaired protein adduct removal following repeat administration of subtoxic doses of acetaminophen enhances liver injury in fed mice.
Nguyen NT; Akakpo JY; Weemhoff JL; Ramachandran A; Ding WX; Jaeschke H
Arch Toxicol; 2021 Apr; 95(4):1463-1473. PubMed ID: 33458793
[TBL] [Abstract][Full Text] [Related]
6. 4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes.
Akakpo JY; Ramachandran A; Kandel SE; Ni HM; Kumer SC; Rumack BH; Jaeschke H
Hum Exp Toxicol; 2018 Dec; 37(12):1310-1322. PubMed ID: 29739258
[TBL] [Abstract][Full Text] [Related]
7. Increased liver-specific proteins in circulating extracellular vesicles as potential biomarkers for drug- and alcohol-induced liver injury.
Cho YE; Im EJ; Moon PG; Mezey E; Song BJ; Baek MC
PLoS One; 2017; 12(2):e0172463. PubMed ID: 28225807
[TBL] [Abstract][Full Text] [Related]
8. Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice.
Nguyen NT; Du K; Akakpo JY; Umbaugh DS; Jaeschke H; Ramachandran A
Toxicol Lett; 2021 Mar; 338():21-31. PubMed ID: 33290831
[TBL] [Abstract][Full Text] [Related]
9. Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans.
Yu D; Wu L; Gill P; Tolleson WH; Chen S; Sun J; Knox B; Jin Y; Xiao W; Hong H; Wang Y; Ren Z; Guo L; Mei N; Guo Y; Yang X; Shi L; Chen Y; Zeng L; Dreval K; Tryndyak V; Pogribny I; Fang H; Shi T; McCullough S; Bhattacharyya S; Schnackenberg L; Mattes W; Beger RD; James L; Tong W; Ning B
Arch Toxicol; 2018 Feb; 92(2):845-858. PubMed ID: 29067470
[TBL] [Abstract][Full Text] [Related]
10. Acetaminophen-cysteine adducts during therapeutic dosing and following overdose.
Heard KJ; Green JL; James LP; Judge BS; Zolot L; Rhyee S; Dart RC
BMC Gastroenterol; 2011 Mar; 11():20. PubMed ID: 21401949
[TBL] [Abstract][Full Text] [Related]
11. Liver-Specific Deletion of Integrin-Linked Kinase in Mice Attenuates Hepatotoxicity and Improves Liver Regeneration After Acetaminophen Overdose.
Bhushan B; Edwards G; Desai A; Michalopoulos GK; Apte U
Gene Expr; 2016; 17(1):35-45. PubMed ID: 27125733
[TBL] [Abstract][Full Text] [Related]
12. Early acetaminophen-protein adducts predict hepatotoxicity following overdose (ATOM-5).
Chiew AL; James LP; Isbister GK; Pickering JW; McArdle K; Chan BSH; Buckley NA
J Hepatol; 2020 Mar; 72(3):450-462. PubMed ID: 31760072
[TBL] [Abstract][Full Text] [Related]
13. Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice.
Ni HM; McGill MR; Chao X; Du K; Williams JA; Xie Y; Jaeschke H; Ding WX
J Hepatol; 2016 Aug; 65(2):354-62. PubMed ID: 27151180
[TBL] [Abstract][Full Text] [Related]
14. The p21
Umbaugh DS; Nguyen NT; Smith SH; Ramachandran A; Jaeschke H
Toxicology; 2024 May; 504():153804. PubMed ID: 38614205
[TBL] [Abstract][Full Text] [Related]
15. Acetaminophen Adducts Detected in Serum of Pediatric Patients With Acute Liver Failure.
Alonso EM; James LP; Zhang S; Squires RH;
J Pediatr Gastroenterol Nutr; 2015 Jul; 61(1):102-7. PubMed ID: 25859823
[TBL] [Abstract][Full Text] [Related]
16. Suppression of iron mobilization from lysosomes to mitochondria attenuates liver injury after acetaminophen overdose in vivo in mice: Protection by minocycline.
Hu J; Lemasters JJ
Toxicol Appl Pharmacol; 2020 Apr; 392():114930. PubMed ID: 32109512
[TBL] [Abstract][Full Text] [Related]
17. HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity.
McGill MR; Yan HM; Ramachandran A; Murray GJ; Rollins DE; Jaeschke H
Hepatology; 2011 Mar; 53(3):974-82. PubMed ID: 21319200
[TBL] [Abstract][Full Text] [Related]
18. Acetaminophen: Dose-Dependent Drug Hepatotoxicity and Acute Liver Failure in Patients.
Jaeschke H
Dig Dis; 2015; 33(4):464-71. PubMed ID: 26159260
[TBL] [Abstract][Full Text] [Related]
19. Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses.
Du K; McGill MR; Xie Y; Jaeschke H
Food Chem Toxicol; 2015 Dec; 86():253-61. PubMed ID: 26522885
[TBL] [Abstract][Full Text] [Related]
20. Exogenous exosomes from mice with acetaminophen-induced liver injury promote toxicity in the recipient hepatocytes and mice.
Cho YE; Seo W; Kim DK; Moon PG; Kim SH; Lee BH; Song BJ; Baek MC
Sci Rep; 2018 Oct; 8(1):16070. PubMed ID: 30375433
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
