These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 30451856)

  • 1. Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity.
    Kubota T; Inoue M; Kubota N; Takamoto I; Mineyama T; Iwayama K; Tokuyama K; Moroi M; Ueki K; Yamauchi T; Kadowaki T
    Nat Commun; 2018 Nov; 9(1):4863. PubMed ID: 30451856
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions.
    Nakahara M; Ito H; Skinner JT; Lin Q; Tamosiuniene R; Nicolls MR; Keegan AD; Johns RA; Yamaji-Kegan K
    Am J Physiol Lung Cell Mol Physiol; 2021 Aug; 321(2):L416-L428. PubMed ID: 34189964
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammation.
    Dasgupta P; Dorsey NJ; Li J; Qi X; Smith EP; Yamaji-Kegan K; Keegan AD
    Sci Signal; 2016 Jun; 9(433):ra63. PubMed ID: 27330190
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages.
    Zheng C; Yang Q; Xu C; Shou P; Cao J; Jiang M; Chen Q; Cao G; Han Y; Li F; Cao W; Zhang L; Zhang L; Shi Y; Wang Y
    Proc Natl Acad Sci U S A; 2015 Dec; 112(52):E7239-48. PubMed ID: 26669445
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance.
    Nara N; Nakayama Y; Okamoto S; Tamura H; Kiyono M; Muraoka M; Tanaka K; Taya C; Shitara H; Ishii R; Yonekawa H; Minokoshi Y; Hara T
    J Biol Chem; 2007 Oct; 282(42):30794-803. PubMed ID: 17724031
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin signaling pathway protects neuronal cell lines by Sirt3 mediated IRS2 activation.
    Mishra N; Lata S; Deshmukh P; Kamat K; Surolia A; Banerjee T
    Biofactors; 2018 May; 44(3):224-236. PubMed ID: 29411439
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular mechanisms of atherosclerosis in metabolic syndrome: role of reduced IRS2-dependent signaling.
    González-Navarro H; Vinué A; Vila-Caballer M; Fortuño A; Beloqui O; Zalba G; Burks D; Díez J; Andrés V
    Arterioscler Thromb Vasc Biol; 2008 Dec; 28(12):2187-94. PubMed ID: 18802016
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin Activates Vagal Afferent Neurons Including those Innervating Pancreas via Insulin Cascade and Ca(2+) Influx: Its Dysfunction in IRS2-KO Mice with Hyperphagic Obesity.
    Iwasaki Y; Shimomura K; Kohno D; Dezaki K; Ayush EA; Nakabayashi H; Kubota N; Kadowaki T; Kakei M; Nakata M; Yada T
    PLoS One; 2013; 8(6):e67198. PubMed ID: 23840624
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance.
    Qi Y; Xu Z; Zhu Q; Thomas C; Kumar R; Feng H; Dostal DE; White MF; Baker KM; Guo S
    Diabetes; 2013 Nov; 62(11):3887-900. PubMed ID: 24159000
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice.
    González-Rodríguez A; Mas Gutierrez JA; Sanz-González S; Ros M; Burks DJ; Valverde AM
    Diabetes; 2010 Mar; 59(3):588-99. PubMed ID: 20028942
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway
    Zhao H; Lu J; He F; Wang M; Yan Y; Chen B; Xie D; Xu C; Wang Q; Liu W; Yu W; Xi Y; Yu L; Yamamoto T; Koyama H; Wang W; Zhang C; Cheng J
    Front Immunol; 2022; 13():931087. PubMed ID: 36177037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.
    Xuan S; Szabolcs M; Cinti F; Perincheri S; Accili D; Efstratiadis A
    J Biol Chem; 2010 Dec; 285(52):41044-50. PubMed ID: 20947509
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity.
    Kubota N; Kubota T; Kajiwara E; Iwamura T; Kumagai H; Watanabe T; Inoue M; Takamoto I; Sasako T; Kumagai K; Kohjima M; Nakamuta M; Moroi M; Sugi K; Noda T; Terauchi Y; Ueki K; Kadowaki T
    Nat Commun; 2016 Oct; 7():12977. PubMed ID: 27708333
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of dehydroepiandrosterone (DHEA) on Akt and protein kinase C zeta (PKCζ) phosphorylation in different tissues of C57BL6, insulin receptor substrate (IRS)1(-/-), and IRS2(-/-) male mice fed a high-fat diet.
    Aoki K; Tajima K; Taguri M; Terauchi Y
    J Steroid Biochem Mol Biol; 2016 May; 159():110-20. PubMed ID: 26976654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity.
    Rached MT; Millership SJ; Pedroni SMA; Choudhury AI; Costa ASH; Hardy DG; Glegola JA; Irvine EE; Selman C; Woodberry MC; Yadav VK; Khadayate S; Vidal-Puig A; Virtue S; Frezza C; Withers DJ
    Mol Metab; 2019 Feb; 20():38-50. PubMed ID: 30553769
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice.
    Arroba AI; Revuelta-Cervantes J; Menes L; González-Rodríguez Á; Pardo V; de la Villa P; Burks DJ; Valverde ÁM
    Invest Ophthalmol Vis Sci; 2013 Jun; 54(6):4215-25. PubMed ID: 23702782
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adipogenic miR-27a in adipose tissue upregulates macrophage activation via inhibiting PPARγ of insulin resistance induced by high-fat diet-associated obesity.
    Yao F; Yu Y; Feng L; Li J; Zhang M; Lan X; Yan X; Liu Y; Guan F; Zhang M; Chen L
    Exp Cell Res; 2017 Jun; 355(2):105-112. PubMed ID: 28365247
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Roles of Insulin Receptor Substrates (IRS) in renal function and renal hemodynamics.
    Hashimoto S; Maoka T; Kawata T; Mochizuki T; Koike T; Shigematsu T
    PLoS One; 2020; 15(12):e0242332. PubMed ID: 33270683
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High Glucose Impairs Insulin Signaling in the Glomerulus: An In Vitro and Ex Vivo Approach.
    Katsoulieris EN; Drossopoulou GI; Kotsopoulou ES; Vlahakos DV; Lianos EA; Tsilibary EC
    PLoS One; 2016; 11(7):e0158873. PubMed ID: 27434075
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects.
    Rametta R; Mozzi E; Dongiovanni P; Motta BM; Milano M; Roviaro G; Fargion S; Valenti L
    Int J Obes (Lond); 2013 Jul; 37(7):986-92. PubMed ID: 23147115
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.