140 related articles for article (PubMed ID: 30452225)
1. Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents.
Semenova MN; Demchuk DV; Tsyganov DV; Chernysheva NB; Samet AV; Silyanova EA; Kislyi VP; Maksimenko AS; Varakutin AE; Konyushkin LD; Raihstat MM; Kiselyov AS; Semenov VV
ACS Comb Sci; 2018 Dec; 20(12):700-721. PubMed ID: 30452225
[TBL] [Abstract][Full Text] [Related]
2. 3-(5-)-Amino-o-diarylisoxazoles: regioselective synthesis and antitubulin activity.
Tsyganov DV; Khrustalev VN; Konyushkin LD; Raihstat MM; Firgang SI; Semenov RV; Kiselyov AS; Semenova MN; Semenov VV
Eur J Med Chem; 2014 Feb; 73():112-25. PubMed ID: 24388833
[TBL] [Abstract][Full Text] [Related]
3. cis-Restricted 3-aminopyrazole analogues of combretastatins: synthesis from plant polyalkoxybenzenes and biological evaluation in the cytotoxicity and phenotypic sea urchin embryo assays.
Tsyganov DV; Konyushkin LD; Karmanova IB; Firgang SI; Strelenko YA; Semenova MN; Kiselyov AS; Semenov VV
J Nat Prod; 2013 Aug; 76(8):1485-91. PubMed ID: 23924236
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines.
Demchuk DV; Samet AV; Chernysheva NB; Ushkarov VI; Stashina GA; Konyushkin LD; Raihstat MM; Firgang SI; Philchenkov AA; Zavelevich MP; Kuiava LM; Chekhun VF; Blokhin DY; Kiselyov AS; Semenova MN; Semenov VV
Bioorg Med Chem; 2014 Jan; 22(2):738-55. PubMed ID: 24387982
[TBL] [Abstract][Full Text] [Related]
5. Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays.
Semenova MN; Kiselyov AS; Tsyganov DV; Konyushkin LD; Firgang SI; Semenov RV; Malyshev OR; Raihstat MM; Fuchs F; Stielow A; Lantow M; Philchenkov AA; Zavelevich MP; Zefirov NS; Kuznetsov SA; Semenov VV
J Med Chem; 2011 Oct; 54(20):7138-49. PubMed ID: 21916509
[TBL] [Abstract][Full Text] [Related]
6. Comparative in vivo evaluation of polyalkoxy substituted 4H-chromenes and oxa-podophyllotoxins as microtubule destabilizing agents in the phenotypic sea urchin embryo assay.
Semenova MN; Tsyganov DV; Malyshev OR; Ershov OV; Bardasov IN; Semenov RV; Kiselyov AS; Semenov VV
Bioorg Med Chem Lett; 2014 Aug; 24(16):3914-8. PubMed ID: 24997684
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and comparative evaluation of 4-oxa- and 4-aza-podophyllotoxins as antiproliferative microtubule destabilizing agents.
Chernysheva NB; Tsyganov DV; Philchenkov AA; Zavelevich MP; Kiselyov AS; Semenov RV; Semenova MN; Semenov VV
Bioorg Med Chem Lett; 2012 Apr; 22(7):2590-3. PubMed ID: 22370267
[TBL] [Abstract][Full Text] [Related]
8. Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents.
Liou JP; Mahindroo N; Chang CW; Guo FM; Lee SW; Tan UK; Yeh TK; Kuo CC; Chang YW; Lu PH; Tung YS; Lin KT; Chang JY; Hsieh HP
ChemMedChem; 2006 Oct; 1(10):1106-18. PubMed ID: 16952120
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.
Romagnoli R; Baraldi PG; Salvador MK; Prencipe F; Bertolasi V; Cancellieri M; Brancale A; Hamel E; Castagliuolo I; Consolaro F; Porcù E; Basso G; Viola G
J Med Chem; 2014 Aug; 57(15):6795-808. PubMed ID: 25025853
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of pyrazole/isoxazole linked arylcinnamides as tubulin polymerization inhibitors and potential antiproliferative agents.
Kamal A; Shaik AB; Rao BB; Khan I; Bharath Kumar G; Jain N
Org Biomol Chem; 2015 Oct; 13(40):10162-78. PubMed ID: 26303171
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Balzarini J; Hadfield JA; Brancale A; Hamel E
J Med Chem; 2007 May; 50(9):2273-7. PubMed ID: 17419607
[TBL] [Abstract][Full Text] [Related]
12. Isoxazole-type derivatives related to combretastatin A-4, synthesis and biological evaluation.
Kaffy J; Pontikis R; Carrez D; Croisy A; Monneret C; Florent JC
Bioorg Med Chem; 2006 Jun; 14(12):4067-77. PubMed ID: 16510288
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
Wang F; Yang Z; Liu Y; Ma L; Wu Y; He L; Shao M; Yu K; Wu W; Pu Y; Nie C; Chen L
Bioorg Med Chem; 2015 Jul; 23(13):3337-50. PubMed ID: 25937236
[TBL] [Abstract][Full Text] [Related]
14. In vitro and in vivo antitumor effects of (4-methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone.
Magalhães HI; Bezerra DP; Cavalcanti BC; Wilke DV; Rotta R; de Lima DP; Beatriz A; Alves AP; Bitencourt Fda S; de Figueiredo IS; Alencar NM; Costa-Lotufo LV; Moraes MO; Pessoa C
Cancer Chemother Pharmacol; 2011 Jul; 68(1):45-52. PubMed ID: 20821328
[TBL] [Abstract][Full Text] [Related]
15. Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones.
Chang CY; Chuang HY; Lee HY; Yeh TK; Kuo CC; Chang CY; Chang JY; Liou JP
Eur J Med Chem; 2014 Apr; 77():306-14. PubMed ID: 24657567
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
Sun J; Chen L; Liu C; Wang Z; Zuo D; Pan J; Qi H; Bao K; Wu Y; Zhang W
Chem Biol Drug Des; 2015 Dec; 86(6):1541-7. PubMed ID: 26202587
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
Kamal A; Shaik B; Nayak VL; Nagaraju B; Kapure JS; Shaheer Malik M; Shaik TB; Prasad B
Bioorg Med Chem; 2014 Oct; 22(19):5155-67. PubMed ID: 25192811
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
[TBL] [Abstract][Full Text] [Related]
19. A synthetic derivative of plant allylpolyalkoxybenzenes induces selective loss of motile cilia in sea urchin embryos.
Semenova MN; Tsyganov DV; Yakubov AP; Kiselyov AS; Semenov VV
ACS Chem Biol; 2008 Feb; 3(2):95-100. PubMed ID: 18278850
[TBL] [Abstract][Full Text] [Related]
20. Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin A-1.
Akselsen OW; Odlo K; Cheng JJ; Maccari G; Botta M; Hansen TV
Bioorg Med Chem; 2012 Jan; 20(1):234-42. PubMed ID: 22137934
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]