BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 30452903)

  • 1. Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma.
    Atkinson A; Renziehausen A; Wang H; Lo Nigro C; Lattanzio L; Merlano M; Rao B; Weir L; Evans A; Matin R; Harwood C; Szlosarek P; Pickering JG; Fleming C; Sim VR; Li S; Vasta JT; Raines RT; Boniol M; Thompson A; Proby C; Crook T; Syed N
    J Invest Dermatol; 2019 May; 139(5):1118-1126. PubMed ID: 30452903
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition.
    Xiong G; Deng L; Zhu J; Rychahou PG; Xu R
    BMC Cancer; 2014 Jan; 14():1. PubMed ID: 24383403
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas, and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls.
    Eriksson J; Le Joncour V; Jahkola T; Juteau S; Laakkonen P; Saksela O; Hölttä E
    Mol Oncol; 2020 Apr; 14(4):742-762. PubMed ID: 32053263
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cycloheximide promotes type I collagen maturation mainly via collagen prolyl 4-hydroxylase subunit α2.
    Shi R; Xu M; Ye H; Gao S; Li J; Li H; Li C
    Acta Biochim Biophys Sin (Shanghai); 2022 Dec; 54(12):1832-1840. PubMed ID: 36789685
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma.
    Hatzimichael E; Lo Nigro C; Lattanzio L; Syed N; Shah R; Dasoula A; Janczar K; Vivenza D; Monteverde M; Merlano M; Papoudou-Bai A; Bai M; Schmid P; Stebbing J; Bower M; Dyer MJ; Karran LE; ElguetaKarstegl C; Farrell PJ; Thompson A; Briasoulis E; Crook T
    Br J Cancer; 2012 Oct; 107(8):1423-32. PubMed ID: 22955849
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: possible influence of low oxygen levels.
    Grimmer C; Balbus N; Lang U; Aigner T; Cramer T; Müller L; Swoboda B; Pfander D
    Am J Pathol; 2006 Aug; 169(2):491-502. PubMed ID: 16877351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Post-translationally abnormal collagens of prolyl 3-hydroxylase-2 null mice offer a pathobiological mechanism for the high myopia linked to human LEPREL1 mutations.
    Hudson DM; Joeng KS; Werther R; Rajagopal A; Weis M; Lee BH; Eyre DR
    J Biol Chem; 2015 Mar; 290(13):8613-22. PubMed ID: 25645914
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Collagen prolyl 4-hydroxylases modify tumor progression.
    Shi R; Gao S; Zhang J; Xu J; Graham LM; Yang X; Li C
    Acta Biochim Biophys Sin (Shanghai); 2021 Jul; 53(7):805-814. PubMed ID: 34009234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tissue-specific collagen hydroxylation at GEP/GDP triplets mediated by P4HA2.
    Wilhelm D; Wurtz A; Abouelfarah H; Sanchez G; Bui C; Vincourt JB
    Matrix Biol; 2023 May; 119():141-153. PubMed ID: 37003347
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prognostic and diagnostic roles of prolyl 4-hydroxylase subunit α members in breast cancer.
    Li M; Wang Q; Zheng Q; Wu L; Zhao B; Wu Y
    Biomark Med; 2021 Sep; 15(13):1085-1095. PubMed ID: 34387118
    [No Abstract]   [Full Text] [Related]  

  • 11. Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets.
    Salo AM; Rappu P; Koski MK; Karjalainen E; Izzi V; Drushinin K; Miinalainen I; Käpylä J; Heino J; Myllyharju J
    Matrix Biol; 2024 Jan; 125():73-87. PubMed ID: 38081527
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mannose Binding Lectin Is Hydroxylated by Collagen Prolyl-4-hydroxylase and Inhibited by Some PHD Inhibitors.
    Bhute VJ; Harte J; Houghton JW; Maxwell PH
    Kidney360; 2020 Jun; 1(6):447-457. PubMed ID: 35368589
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Superoxide-induced Type I collagen secretion depends on prolyl 4-hydroxylases.
    Shi R; Gao S; Smith AH; Li H; Shao M; Shangguan J; Zhang J; Xu J; Ye J; Graham LM; Li C
    Biochem Biophys Res Commun; 2020 Sep; 529(4):1011-1017. PubMed ID: 32819558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. P4HA3 is Epigenetically Activated by Slug in Gastric Cancer and its Deregulation is Associated With Enhanced Metastasis and Poor Survival.
    Song H; Liu L; Song Z; Ren Y; Li C; Huo J
    Technol Cancer Res Treat; 2018 Jan; 17():1533033818796485. PubMed ID: 30198421
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Collagen Type X Alpha 1 (COL10A1) Contributes to Cell Proliferation, Migration, and Invasion by Targeting Prolyl 4-Hydroxylase Beta Polypeptide (P4HB) in Breast Cancer.
    Yang W; Wu X; Zhou F
    Med Sci Monit; 2021 Feb; 27():e928919. PubMed ID: 33637669
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer.
    Shah R; Smith P; Purdie C; Quinlan P; Baker L; Aman P; Thompson AM; Crook T
    Br J Cancer; 2009 May; 100(10):1687-96. PubMed ID: 19436308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells.
    Luo Y; Xu W; Chen H; Warburton D; Dong R; Qian B; Selman M; Gauldie J; Kolb M; Shi W
    J Pathol; 2015 Jul; 236(3):384-94. PubMed ID: 25779936
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.
    Kiriakidis S; Hoer SS; Burrows N; Biddlecome G; Khan MN; Thinnes CC; Schofield CJ; Rogers N; Botto M; Paleolog E; Maxwell PH
    Kidney Int; 2017 Oct; 92(4):900-908. PubMed ID: 28506759
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of prolyl hydroxylation in the molecular interactions of collagens.
    Rappu P; Salo AM; Myllyharju J; Heino J
    Essays Biochem; 2019 Sep; 63(3):325-335. PubMed ID: 31350381
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of prolyl 3-hydroxylase genes in embryonic and adult mouse tissues.
    Vranka J; Stadler HS; Bächinger HP
    Cell Struct Funct; 2009; 34(2):97-104. PubMed ID: 19652424
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.