BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 30463694)

  • 1. Fine-tuning of the stability of β-strands by Y181 in perfringolysin O directs the prepore to pore transition.
    Kulma M; Kacprzyk-Stokowiec A; Traczyk G; Kwiatkowska K; Dadlez M
    Biochim Biophys Acta Biomembr; 2019 Jan; 1861(1):110-122. PubMed ID: 30463694
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crucial role of perfringolysin O D1 domain in orchestrating structural transitions leading to membrane-perforating pores: a hydrogen-deuterium exchange study.
    Kacprzyk-Stokowiec A; Kulma M; Traczyk G; Kwiatkowska K; Sobota A; Dadlez M
    J Biol Chem; 2014 Oct; 289(41):28738-52. PubMed ID: 25164812
    [TBL] [Abstract][Full Text] [Related]  

  • 3. R468A mutation in perfringolysin O destabilizes toxin structure and induces membrane fusion.
    Kulma M; Kacprzyk-Stokowiec A; Kwiatkowska K; Traczyk G; Sobota A; Dadlez M
    Biochim Biophys Acta Biomembr; 2017 Jun; 1859(6):1075-1088. PubMed ID: 28263714
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformational changes that effect oligomerization and initiate pore formation are triggered throughout perfringolysin O upon binding to cholesterol.
    Heuck AP; Savva CG; Holzenburg A; Johnson AE
    J Biol Chem; 2007 Aug; 282(31):22629-37. PubMed ID: 17553799
    [TBL] [Abstract][Full Text] [Related]  

  • 5. How interaction of perfringolysin O with membranes is controlled by sterol structure, lipid structure, and physiological low pH: insights into the origin of perfringolysin O-lipid raft interaction.
    Nelson LD; Johnson AE; London E
    J Biol Chem; 2008 Feb; 283(8):4632-42. PubMed ID: 18089559
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy.
    Dang TX; Hotze EM; Rouiller I; Tweten RK; Wilson-Kubalek EM
    J Struct Biol; 2005 Apr; 150(1):100-8. PubMed ID: 15797734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An Intermolecular π-Stacking Interaction Drives Conformational Changes Necessary to β-Barrel Formation in a Pore-Forming Toxin.
    Burns JR; Morton CJ; Parker MW; Tweten RK
    mBio; 2019 Jul; 10(4):. PubMed ID: 31266869
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin.
    Hotze EM; Heuck AP; Czajkowsky DM; Shao Z; Johnson AE; Tweten RK
    J Biol Chem; 2002 Mar; 277(13):11597-605. PubMed ID: 11799121
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perfringolysin O structure and mechanism of pore formation as a paradigm for cholesterol-dependent cytolysins.
    Johnson BB; Heuck AP
    Subcell Biochem; 2014; 80():63-81. PubMed ID: 24798008
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Perfringolysin O: The Underrated Clostridium perfringens Toxin?
    Verherstraeten S; Goossens E; Valgaeren B; Pardon B; Timbermont L; Haesebrouck F; Ducatelle R; Deprez P; Wade KR; Tweten R; Van Immerseel F
    Toxins (Basel); 2015 May; 7(5):1702-21. PubMed ID: 26008232
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disulfide-bond scanning reveals assembly state and β-strand tilt angle of the PFO β-barrel.
    Sato TK; Tweten RK; Johnson AE
    Nat Chem Biol; 2013 Jun; 9(6):383-9. PubMed ID: 23563525
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: an alpha-helical to beta-sheet transition identified by fluorescence spectroscopy.
    Shepard LA; Heuck AP; Hamman BD; Rossjohn J; Parker MW; Ryan KR; Johnson AE; Tweten RK
    Biochemistry; 1998 Oct; 37(41):14563-74. PubMed ID: 9772185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane.
    Czajkowsky DM; Hotze EM; Shao Z; Tweten RK
    EMBO J; 2004 Aug; 23(16):3206-15. PubMed ID: 15297878
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of Cholesterol with Perfringolysin O: What Have We Learned from Functional Analysis?
    Savinov SN; Heuck AP
    Toxins (Basel); 2017 Nov; 9(12):. PubMed ID: 29168745
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins.
    Shepard LA; Shatursky O; Johnson AE; Tweten RK
    Biochemistry; 2000 Aug; 39(33):10284-93. PubMed ID: 10956018
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin.
    Ramachandran R; Heuck AP; Tweten RK; Johnson AE
    Nat Struct Biol; 2002 Nov; 9(11):823-7. PubMed ID: 12368903
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Decreasing Transmembrane Segment Length Greatly Decreases Perfringolysin O Pore Size.
    Lin Q; Wang T; Li H; London E
    J Membr Biol; 2015 Jun; 248(3):517-27. PubMed ID: 25850715
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins.
    Shatursky O; Heuck AP; Shepard LA; Rossjohn J; Parker MW; Johnson AE; Tweten RK
    Cell; 1999 Oct; 99(3):293-9. PubMed ID: 10555145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insight into the Structural Dynamics of the Lysenin During Prepore-to-Pore Transition Using Hydrogen-Deuterium Exchange Mass Spectrometry.
    Kulma M; Dadlez M; Kwiatkowska K
    Toxins (Basel); 2019 Aug; 11(8):. PubMed ID: 31394843
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion.
    Nakamura M; Sekino N; Iwamoto M; Ohno-Iwashita Y
    Biochemistry; 1995 May; 34(19):6513-20. PubMed ID: 7756282
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.