These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 30466996)

  • 1. Identification of amentoflavone as a potent highly selective PARP-1 inhibitor and its potentiation on carboplatin in human non-small cell lung cancer.
    Hu XL; Feng JH; Pham TA; Ma HY; Ma MX; Song R; Shen W; Xiong F; Zhang XQ; Ye WC; Wang H
    Phytomedicine; 2018 Nov; 50():88-98. PubMed ID: 30466996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of amentoflavone metabolites on PARP-1 inhibition and the potentiation on anti-proliferative effects of carboplatin in A549 cells.
    Wang B; Hu X; Wang R; Long H; Wang H
    Bioorg Med Chem Lett; 2022 Jan; 56():128480. PubMed ID: 34843914
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of Novel Apigenin-Piperazine Hybrids as Potent and Selective Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors for the Treatment of Cancer.
    Long H; Hu X; Wang B; Wang Q; Wang R; Liu S; Xiong F; Jiang Z; Zhang XQ; Ye WC; Wang H
    J Med Chem; 2021 Aug; 64(16):12089-12108. PubMed ID: 34404206
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer.
    Almahli H; Hadchity E; Jaballah MY; Daher R; Ghabbour HA; Kabil MM; Al-Shakliah NS; Eldehna WM
    Bioorg Chem; 2018 Apr; 77():443-456. PubMed ID: 29453076
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo.
    Jung YJ; Lee EH; Lee CG; Rhee KJ; Jung WS; Choi Y; Pan CH; Kang K
    J Ethnopharmacol; 2017 Apr; 202():78-84. PubMed ID: 28286104
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials.
    Yuan B; Ye N; Song SS; Wang YT; Song Z; Chen HD; Chen CH; Huan XJ; Wang YQ; Su Y; Shen YY; Sun YM; Yang XY; Chen Y; Guo SY; Gan Y; Gao ZW; Chen XY; Ding J; He JX; Zhang A; Miao ZH
    Cancer Lett; 2017 Feb; 386():47-56. PubMed ID: 27847302
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells.
    Min A; Im SA; Kim DK; Song SH; Kim HJ; Lee KH; Kim TY; Han SW; Oh DY; Kim TY; O'Connor MJ; Bang YJ
    Breast Cancer Res; 2015 Mar; 17():33. PubMed ID: 25888415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors.
    Gao CZ; Dong W; Cui ZW; Yuan Q; Hu XM; Wu QM; Han X; Xu Y; Min ZL
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):150-162. PubMed ID: 30427217
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of erythrina-based PARP-1/FTase dual-target inhibitors against lung cancer epithelial-mesenchymal transition (EMT) in vivo and in vitro.
    Yu L; Wang YD; Yan ZW; Zhang LY; Li S
    Bioorg Chem; 2024 Jul; 148():107480. PubMed ID: 38772291
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of PARP-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft.
    Senra JM; Telfer BA; Cherry KE; McCrudden CM; Hirst DG; O'Connor MJ; Wedge SR; Stratford IJ
    Mol Cancer Ther; 2011 Oct; 10(10):1949-58. PubMed ID: 21825006
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Effect and Mechanism of Radiosensitization of Poly (ADP-Ribose) Polymerase Inhibitor n Lewis Cells and Xenografts].
    Wang W; Duan B; Zeng L
    Zhongguo Fei Ai Za Zhi; 2016 Jan; 19(1):16-23. PubMed ID: 26805733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phytochemical naphtho[1,2-b] furan-4,5‑dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer.
    Chien CM; Yang JC; Wu PH; Wu CY; Chen GY; Wu YC; Chou CK; Tseng CH; Chen YL; Wang LF; Chiu CC
    Phytomedicine; 2019 Feb; 54():109-119. PubMed ID: 30668360
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The antipsychotic agent flupentixol is a new PI3K inhibitor and potential anticancer drug for lung cancer.
    Dong C; Chen Y; Li H; Yang Y; Zhang H; Ke K; Shi XN; Liu X; Li L; Ma J; Kung HF; Chen C; Lin MC
    Int J Biol Sci; 2019; 15(7):1523-1532. PubMed ID: 31337981
    [No Abstract]   [Full Text] [Related]  

  • 14. PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors.
    Parsels LA; Karnak D; Parsels JD; Zhang Q; Vélez-Padilla J; Reichert ZR; Wahl DR; Maybaum J; O'Connor MJ; Lawrence TS; Morgan MA
    Mol Cancer Res; 2018 Feb; 16(2):222-232. PubMed ID: 29133592
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The combination of artesunate and carboplatin exerts a synergistic anti-tumour effect on non-small cell lung cancer.
    Wang Z; Wang Q; He T; Li W; Liu Y; Fan Y; Wang Y; Wang Q; Chen J
    Clin Exp Pharmacol Physiol; 2020 Jun; 47(6):1083-1091. PubMed ID: 32072678
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p38 MAPK inhibitor SB203580 enhances anticancer activity of PARP inhibitor olaparib in a synergistic way on non-small cell lung carcinoma A549 cells.
    Dey P; Biswas S; Das R; Chatterjee S; Ghosh U
    Biochem Biophys Res Commun; 2023 Aug; 670():55-62. PubMed ID: 37276791
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor Activity of a Novel Tyrosine Kinase Inhibitor AIU2001 Due to Abrogation of the DNA Damage Repair in Non-Small Cell Lung Cancer Cells.
    Ryu H; Choi HK; Kim HJ; Kim AY; Song JY; Hwang SG; Kim JS; Kim DU; Kim EH; Kim J; Ahn J
    Int J Mol Sci; 2019 Sep; 20(19):. PubMed ID: 31554189
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking and Biological Evaluation for Identification of Potential Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors.
    Zhou Y; Tang S; Chen T; Niu MM
    Molecules; 2019 Nov; 24(23):. PubMed ID: 31766720
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.
    Ye YT; Zhong W; Sun P; Wang D; Wang C; Hu LM; Qian JQ
    J Ethnopharmacol; 2017 Mar; 200():107-116. PubMed ID: 28088493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy.
    Chen WH; Song SS; Qi MH; Huan XJ; Wang YQ; Jiang H; Ding J; Ren GB; Miao ZH; Li J
    Acta Pharmacol Sin; 2017 Nov; 38(11):1521-1532. PubMed ID: 28770827
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.