BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1002 related articles for article (PubMed ID: 30467171)

  • 1. ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.
    Rühl S; Shkarina K; Demarco B; Heilig R; Santos JC; Broz P
    Science; 2018 Nov; 362(6417):956-960. PubMed ID: 30467171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
    He WT; Wan H; Hu L; Chen P; Wang X; Huang Z; Yang ZH; Zhong CQ; Han J
    Cell Res; 2015 Dec; 25(12):1285-98. PubMed ID: 26611636
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
    Shi J; Zhao Y; Wang K; Shi X; Wang Y; Huang H; Zhuang Y; Cai T; Wang F; Shao F
    Nature; 2015 Oct; 526(7575):660-5. PubMed ID: 26375003
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Live-cell visualization of gasdermin D-driven pyroptotic cell death.
    Rathkey JK; Benson BL; Chirieleison SM; Yang J; Xiao TS; Dubyak GR; Huang AY; Abbott DW
    J Biol Chem; 2017 Sep; 292(35):14649-14658. PubMed ID: 28726636
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.
    Yang J; Liu Z; Wang C; Yang R; Rathkey JK; Pinkard OW; Shi W; Chen Y; Dubyak GR; Abbott DW; Xiao TS
    Proc Natl Acad Sci U S A; 2018 Jun; 115(26):6792-6797. PubMed ID: 29891674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
    Kayagaki N; Stowe IB; Lee BL; O'Rourke K; Anderson K; Warming S; Cuellar T; Haley B; Roose-Girma M; Phung QT; Liu PS; Lill JR; Li H; Wu J; Kummerfeld S; Zhang J; Lee WP; Snipas SJ; Salvesen GS; Morris LX; Fitzgerald L; Zhang Y; Bertram EM; Goodnow CC; Dixit VM
    Nature; 2015 Oct; 526(7575):666-71. PubMed ID: 26375259
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emerging insights into molecular mechanisms underlying pyroptosis and functions of inflammasomes in diseases.
    Lu F; Lan Z; Xin Z; He C; Guo Z; Xia X; Hu T
    J Cell Physiol; 2020 Apr; 235(4):3207-3221. PubMed ID: 31621910
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recent Insights on Inflammasomes, Gasdermin Pores, and Pyroptosis.
    de Vasconcelos NM; Lamkanfi M
    Cold Spring Harb Perspect Biol; 2020 May; 12(5):. PubMed ID: 31570336
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhancing Gasdermin-induced tumor pyroptosis through preventing ESCRT-dependent cell membrane repair augments antitumor immune response.
    Li Z; Mo F; Wang Y; Li W; Chen Y; Liu J; Chen-Mayfield TJ; Hu Q
    Nat Commun; 2022 Oct; 13(1):6321. PubMed ID: 36280674
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages.
    de Vasconcelos NM; Van Opdenbosch N; Van Gorp H; Martín-Pérez R; Zecchin A; Vandenabeele P; Lamkanfi M
    Cell Rep; 2020 Jul; 32(4):107959. PubMed ID: 32726624
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides.
    Russo HM; Rathkey J; Boyd-Tressler A; Katsnelson MA; Abbott DW; Dubyak GR
    J Immunol; 2016 Aug; 197(4):1353-67. PubMed ID: 27385778
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.
    Sborgi L; Rühl S; Mulvihill E; Pipercevic J; Heilig R; Stahlberg H; Farady CJ; Müller DJ; Broz P; Hiller S
    EMBO J; 2016 Aug; 35(16):1766-78. PubMed ID: 27418190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1.
    Ramirez MLG; Poreba M; Snipas SJ; Groborz K; Drag M; Salvesen GS
    J Biol Chem; 2018 May; 293(18):7058-7067. PubMed ID: 29414788
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.
    Schneider KS; Groß CJ; Dreier RF; Saller BS; Mishra R; Gorka O; Heilig R; Meunier E; Dick MS; Ćiković T; Sodenkamp J; Médard G; Naumann R; Ruland J; Kuster B; Broz P; Groß O
    Cell Rep; 2017 Dec; 21(13):3846-3859. PubMed ID: 29281832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against
    Zhu Q; Zheng M; Balakrishnan A; Karki R; Kanneganti TD
    J Immunol; 2018 Dec; 201(12):3662-3668. PubMed ID: 30404813
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients.
    Khanova E; Wu R; Wang W; Yan R; Chen Y; French SW; Llorente C; Pan SQ; Yang Q; Li Y; Lazaro R; Ansong C; Smith RD; Bataller R; Morgan T; Schnabl B; Tsukamoto H
    Hepatology; 2018 May; 67(5):1737-1753. PubMed ID: 29108122
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
    Hu JJ; Liu X; Xia S; Zhang Z; Zhang Y; Zhao J; Ruan J; Luo X; Lou X; Bai Y; Wang J; Hollingsworth LR; Magupalli VG; Zhao L; Luo HR; Kim J; Lieberman J; Wu H
    Nat Immunol; 2020 Jul; 21(7):736-745. PubMed ID: 32367036
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Snapshot of a Deadly Embrace: The Caspase-1-GSDMD Interface.
    Vande Walle L; Lamkanfi M
    Immunity; 2020 Jul; 53(1):6-8. PubMed ID: 32668229
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gasdermin D Protects from Melioidosis through Pyroptosis and Direct Killing of Bacteria.
    Wang J; Deobald K; Re F
    J Immunol; 2019 Jun; 202(12):3468-3473. PubMed ID: 31036765
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis.
    Kang R; Zeng L; Zhu S; Xie Y; Liu J; Wen Q; Cao L; Xie M; Ran Q; Kroemer G; Wang H; Billiar TR; Jiang J; Tang D
    Cell Host Microbe; 2018 Jul; 24(1):97-108.e4. PubMed ID: 29937272
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 51.