These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 30475643)

  • 1. Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2-AMPK-PGC1α signaling pathway.
    Liu B; Jin J; Zhang Z; Zuo L; Jiang M; Xie C
    Biochem Cell Biol; 2019 Aug; 97(4):397-405. PubMed ID: 30475643
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
    Yang W; Liu J; Hou L; Chen Q; Liu Y
    Life Sci; 2021 Jan; 265():118796. PubMed ID: 33220292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma.
    Gong K; Li W
    Free Radic Biol Med; 2011 Dec; 51(12):2259-71. PubMed ID: 22011623
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells.
    Li W; Liu J; Zhao Y
    Mol Carcinog; 2014 May; 53(5):403-12. PubMed ID: 23255458
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PKM2 inhibition may reverse therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma.
    Martin SP; Fako V; Dang H; Dominguez DA; Khatib S; Ma L; Wang H; Zheng W; Wang XW
    J Exp Clin Cancer Res; 2020 Jun; 39(1):99. PubMed ID: 32487192
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Shikonin enhances sensitization of gefitinib against wild-type EGFR non-small cell lung cancer via inhibition PKM2/stat3/cyclinD1 signal pathway.
    Tang JC; Ren YG; Zhao J; Long F; Chen JY; Jiang Z
    Life Sci; 2018 Jul; 204():71-77. PubMed ID: 29738778
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation.
    Li W; Zhang C; Ren A; Li T; Jin R; Li G; Gu X; Shi R; Zhao Y
    PLoS One; 2015; 10(5):e0126459. PubMed ID: 25961580
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways.
    Yang Q; Ji M; Guan H; Shi B; Hou P
    J Clin Endocrinol Metab; 2013 Dec; 98(12):E1909-17. PubMed ID: 24106286
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
    Jing H; Sun W; Fan J; Zhang Y; Yang J; Jia J; Li J; Guo J; Luo S; Zheng Y
    Mol Med Rep; 2016 Apr; 13(4):3009-16. PubMed ID: 26935874
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting Cell Necroptosis and Apoptosis Induced by Shikonin via Receptor Interacting Protein Kinases in Estrogen Receptor Positive Breast Cancer Cell Line, MCF-7.
    Shahsavari Z; Karami-Tehrani F; Salami S
    Anticancer Agents Med Chem; 2018; 18(2):245-254. PubMed ID: 28933271
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antitumor Effect of Shikonin, a PKM2 Inhibitor, in Cholangiocarcinoma Cell Lines.
    Thonsri U; Seubwai W; Waraasawapati S; Wongkham S; Boonmars T; Cha'on U; Wongkham C
    Anticancer Res; 2020 Sep; 40(9):5115-5124. PubMed ID: 32878800
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Plumbagin inhibits proliferation and induces apoptosis of hepatocellular carcinoma by downregulating the expression of SIVA.
    Li T; Lv M; Chen X; Yu Y; Zang G; Tang Z
    Drug Des Devel Ther; 2019; 13():1289-1300. PubMed ID: 31118568
    [No Abstract]   [Full Text] [Related]  

  • 13. Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma.
    Gong K; Zhang Z; Chen Y; Shu HB; Li W
    Eur J Pharmacol; 2014 Sep; 738():142-52. PubMed ID: 24886888
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sauchinone exerts anticancer effects by targeting AMPK signaling in hepatocellular carcinoma cells.
    Kim YW; Jang EJ; Kim CH; Lee JH
    Chem Biol Interact; 2017 Jan; 261():108-117. PubMed ID: 27871897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Shikonin inhibits the proliferation and induces the apoptosis of human HepG2 cells.
    Yingkun N; Lvsong Z; Huimin Y
    Can J Physiol Pharmacol; 2010 Dec; 88(12):1138-46. PubMed ID: 21164560
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Advance in Anti-tumor Mechanisms of Shikonin, Alkannin and their Derivatives.
    Zhang X; Cui JH; Meng QQ; Li SS; Zhou W; Xiao S
    Mini Rev Med Chem; 2018; 18(2):164-172. PubMed ID: 28245783
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
    Xu Q; Tu J; Dou C; Zhang J; Yang L; Liu X; Lei K; Liu Z; Wang Y; Li L; Bao H; Wang J; Tu K
    Mol Cancer; 2017 Dec; 16(1):178. PubMed ID: 29262861
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis.
    Zhao X; Zhu Y; Hu J; Jiang L; Li L; Jia S; Zen K
    Sci Rep; 2018 Sep; 8(1):14517. PubMed ID: 30266938
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autophagy induction by xanthoangelol exhibits anti-metastatic activities in hepatocellular carcinoma.
    Yang X; Xie J; Liu X; Li Z; Fang K; Zhang L; Han M; Zhang Z; Gong Z; Lin X; Shi X; Gao H; Lu K
    Cell Biochem Funct; 2019 Apr; 37(3):128-138. PubMed ID: 30883849
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Shikonin Attenuates Hepatic Steatosis by Enhancing Beta Oxidation and Energy Expenditure via AMPK Activation.
    Gwon SY; Ahn J; Jung CH; Moon B; Ha TY
    Nutrients; 2020 Apr; 12(4):. PubMed ID: 32316687
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.