BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 30476359)

  • 1. Binding of a Telomestatin Derivative Changes the Mechanical Anisotropy of a Human Telomeric G-Quadruplex.
    Jonchhe S; Ghimire C; Cui Y; Sasaki S; McCool M; Park S; Iida K; Nagasawa K; Sugiyama H; Mao H
    Angew Chem Int Ed Engl; 2019 Jan; 58(3):877-881. PubMed ID: 30476359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding of Telomestatin to a Telomeric G-Quadruplex DNA Probed by All-Atom Molecular Dynamics Simulations with Explicit Solvent.
    Mulholland K; Wu C
    J Chem Inf Model; 2016 Oct; 56(10):2093-2102. PubMed ID: 27632666
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Solution structure of an intramolecular (3 + 1) human telomeric G-quadruplex bound to a telomestatin derivative.
    Chung WJ; Heddi B; Tera M; Iida K; Nagasawa K; Phan AT
    J Am Chem Soc; 2013 Sep; 135(36):13495-501. PubMed ID: 23909929
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Adaptive and Specific Recognition of Telomeric G-Quadruplexes via Polyvalency Induced Unstacking of Binding Units.
    Abraham Punnoose J; Ma Y; Li Y; Sakuma M; Mandal S; Nagasawa K; Mao H
    J Am Chem Soc; 2017 Jun; 139(22):7476-7484. PubMed ID: 28505453
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex.
    Kim MY; Vankayalapati H; Shin-Ya K; Wierzba K; Hurley LH
    J Am Chem Soc; 2002 Mar; 124(10):2098-9. PubMed ID: 11878947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Energetics of the human Tel-22 quadruplex-telomestatin interaction: a molecular dynamics study.
    Agrawal S; Ojha RP; Maiti S
    J Phys Chem B; 2008 Jun; 112(22):6828-36. PubMed ID: 18461983
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Telomestatin: formal total synthesis and cation-mediated interaction of its seco-derivatives with G-quadruplexes.
    Linder J; Garner TP; Williams HE; Searle MS; Moody CJ
    J Am Chem Soc; 2011 Feb; 133(4):1044-51. PubMed ID: 21162526
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains.
    Ma Y; Iida K; Sasaki S; Hirokawa T; Heddi B; Phan AT; Nagasawa K
    Molecules; 2019 Jan; 24(2):. PubMed ID: 30642002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry.
    Rosu F; Gabelica V; Shin-ya K; De Pauw E
    Chem Commun (Camb); 2003 Nov; (21):2702-3. PubMed ID: 14649819
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of telomestatin with the telomeric single-strand overhang.
    Gomez D; Paterski R; Lemarteleur T; Shin-Ya K; Mergny JL; Riou JF
    J Biol Chem; 2004 Oct; 279(40):41487-94. PubMed ID: 15277522
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure.
    Rezler EM; Seenisamy J; Bashyam S; Kim MY; White E; Wilson WD; Hurley LH
    J Am Chem Soc; 2005 Jul; 127(26):9439-47. PubMed ID: 15984871
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The polymorphisms of DNA G-quadruplex investigated by docking experiments with telomestatin enantiomers.
    Alcaro S; Costa G; Distinto S; Moraca F; Ortuso F; Parrotta L; Artese A
    Curr Pharm Des; 2012; 18(14):1873-9. PubMed ID: 22376115
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells.
    Gomez D; O'Donohue MF; Wenner T; Douarre C; Macadré J; Koebel P; Giraud-Panis MJ; Kaplan H; Kolkes A; Shin-ya K; Riou JF
    Cancer Res; 2006 Jul; 66(14):6908-12. PubMed ID: 16849533
    [TBL] [Abstract][Full Text] [Related]  

  • 14. G-quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer.
    Iida K; Tera M; Shin-Ya K; Nagasawa K
    Nucleic Acids Symp Ser (Oxf); 2009; (53):233-4. PubMed ID: 19749346
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stabilization of telomeric G-quadruplex by ligand binding increases susceptibility to S1 nuclease.
    Ishikawa R; Yasuda M; Sasaki S; Ma Y; Nagasawa K; Tera M
    Chem Commun (Camb); 2021 Jul; 57(59):7236-7239. PubMed ID: 34263271
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct quantification of loop interaction and π-π stacking for G-quadruplex stability at the submolecular level.
    Ghimire C; Park S; Iida K; Yangyuoru P; Otomo H; Yu Z; Nagasawa K; Sugiyama H; Mao H
    J Am Chem Soc; 2014 Nov; 136(44):15537-44. PubMed ID: 25296000
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA.
    Barbieri CM; Srinivasan AR; Rzuczek SG; Rice JE; LaVoie EJ; Pilch DS
    Nucleic Acids Res; 2007; 35(10):3272-86. PubMed ID: 17452355
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells.
    Temime-Smaali N; Guittat L; Sidibe A; Shin-ya K; Trentesaux C; Riou JF
    PLoS One; 2009 Sep; 4(9):e6919. PubMed ID: 19742304
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of unsymmetric macrocyclic hexaoxazole compounds with an ability to induce distinct G-quadruplex topologies in telomeric DNA.
    Sakuma M; Ma Y; Tsushima Y; Iida K; Hirokawa T; Nagasawa K
    Org Biomol Chem; 2016 Jun; 14(22):5109-16. PubMed ID: 27181296
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.
    Sun D; Guo K; Rusche JJ; Hurley LH
    Nucleic Acids Res; 2005; 33(18):6070-80. PubMed ID: 16239639
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.