346 related articles for article (PubMed ID: 30482844)
21. Anti-apoptotic protein BCL-XL as a therapeutic vulnerability in gastric cancer.
Wei Y; Zhang L; Wang C; Li Z; Luo M; Xie G; Yang X; Li M; Ren S; Zhao D; Gao R; Gong JN
Animal Model Exp Med; 2023 Jun; 6(3):245-254. PubMed ID: 37271936
[TBL] [Abstract][Full Text] [Related]
22. BET Inhibitors Potentiate Chemotherapy and Killing of
Tan X; Tong J; Wang YJ; Fletcher R; Schoen RE; Yu J; Shen L; Zhang L
Cancer Res; 2019 Mar; 79(6):1191-1203. PubMed ID: 30674532
[TBL] [Abstract][Full Text] [Related]
23. The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.
da Motta LL; Ledaki I; Purshouse K; Haider S; De Bastiani MA; Baban D; Morotti M; Steers G; Wigfield S; Bridges E; Li JL; Knapp S; Ebner D; Klamt F; Harris AL; McIntyre A
Oncogene; 2017 Jan; 36(1):122-132. PubMed ID: 27292261
[TBL] [Abstract][Full Text] [Related]
24. BET protein proteolysis targeting chimera (PROTAC) exerts potent lethal activity against mantle cell lymphoma cells.
Sun B; Fiskus W; Qian Y; Rajapakshe K; Raina K; Coleman KG; Crew AP; Shen A; Saenz DT; Mill CP; Nowak AJ; Jain N; Zhang L; Wang M; Khoury JD; Coarfa C; Crews CM; Bhalla KN
Leukemia; 2018 Feb; 32(2):343-352. PubMed ID: 28663582
[TBL] [Abstract][Full Text] [Related]
25. Activity of BET-proteolysis targeting chimeric (PROTAC) compounds in triple negative breast cancer.
Noblejas-López MDM; Nieto-Jimenez C; Burgos M; Gómez-Juárez M; Montero JC; Esparís-Ogando A; Pandiella A; Galán-Moya EM; Ocaña A
J Exp Clin Cancer Res; 2019 Aug; 38(1):383. PubMed ID: 31470872
[TBL] [Abstract][Full Text] [Related]
26. LIN9 confers paclitaxel resistance in triple negative breast cancer cells by upregulating CCSAP.
Lai H; Wang R; Li S; Shi Q; Cai Z; Li Y; Liu Y
Sci China Life Sci; 2020 Mar; 63(3):419-428. PubMed ID: 31420851
[TBL] [Abstract][Full Text] [Related]
27. Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-X
Yoon MK; Kim BY; Lee JY; Ha JH; Kim SA; Lee DH; Lee MS; Lee MK; Choi JS; Cho JH; Kim JH; Kim S; Song J; Park SG; Park BC; Bae KH; Choi SU; Chi SW
J Biol Chem; 2018 Dec; 293(51):19546-19558. PubMed ID: 30429221
[TBL] [Abstract][Full Text] [Related]
28. Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer.
Li B; Ni Chonghaile T; Fan Y; Madden SF; Klinger R; O'Connor AE; Walsh L; O'Hurley G; Mallya Udupi G; Joseph J; Tarrant F; Conroy E; Gaber A; Chin SF; Bardwell HA; Provenzano E; Crown J; Dubois T; Linn S; Jirstrom K; Caldas C; O'Connor DP; Gallagher WM
Cancer Res; 2017 Jul; 77(14):3834-3845. PubMed ID: 28455421
[TBL] [Abstract][Full Text] [Related]
29. TH1902, a new docetaxel-peptide conjugate for the treatment of sortilin-positive triple-negative breast cancer.
Demeule M; Charfi C; Currie JC; Larocque A; Zgheib A; Kozelko S; Béliveau R; Marsolais C; Annabi B
Cancer Sci; 2021 Oct; 112(10):4317-4334. PubMed ID: 34314556
[TBL] [Abstract][Full Text] [Related]
30. BCL-xL inhibition potentiates cancer therapies by redirecting the outcome of p53 activation from senescence to apoptosis.
Bharti V; Watkins R; Kumar A; Shattuck-Brandt RL; Mossing A; Mittra A; Shen C; Tsung A; Davies AE; Hanel W; Reneau JC; Chung C; Sizemore GM; Richmond A; Weiss VL; Vilgelm AE
Cell Rep; 2022 Dec; 41(12):111826. PubMed ID: 36543138
[TBL] [Abstract][Full Text] [Related]
31. WBP2 Downregulation Inhibits Proliferation by Blocking YAP Transcription and the EGFR/PI3K/Akt Signaling Pathway in Triple Negative Breast Cancer.
Song H; Wu T; Xie D; Li D; Hua K; Hu J; Fang L
Cell Physiol Biochem; 2018; 48(5):1968-1982. PubMed ID: 30092563
[TBL] [Abstract][Full Text] [Related]
32. Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC).
Welti J; Sharp A; Yuan W; Dolling D; Nava Rodrigues D; Figueiredo I; Gil V; Neeb A; Clarke M; Seed G; Crespo M; Sumanasuriya S; Ning J; Knight E; Francis JC; Hughes A; Halsey WS; Paschalis A; Mani RS; Raj GV; Plymate SR; Carreira S; Boysen G; Chinnaiyan AM; Swain A; de Bono JS;
Clin Cancer Res; 2018 Jul; 24(13):3149-3162. PubMed ID: 29555663
[No Abstract] [Full Text] [Related]
33. Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer.
Bai L; Zhou B; Yang CY; Ji J; McEachern D; Przybranowski S; Jiang H; Hu J; Xu F; Zhao Y; Liu L; Fernandez-Salas E; Xu J; Dou Y; Wen B; Sun D; Meagher J; Stuckey J; Hayes DF; Li S; Ellis MJ; Wang S
Cancer Res; 2017 May; 77(9):2476-2487. PubMed ID: 28209615
[TBL] [Abstract][Full Text] [Related]
34. TIPIN depletion leads to apoptosis in breast cancer cells.
Baldeyron C; Brisson A; Tesson B; Némati F; Koundrioukoff S; Saliba E; De Koning L; Martel E; Ye M; Rigaill G; Meseure D; Nicolas A; Gentien D; Decaudin D; Debatisse M; Depil S; Cruzalegui F; Pierré A; Roman-Roman S; Tucker GC; Dubois T
Mol Oncol; 2015 Oct; 9(8):1580-98. PubMed ID: 26004086
[TBL] [Abstract][Full Text] [Related]
35. Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors.
Li W; Gupta SK; Han W; Kundson RA; Nelson S; Knutson D; Greipp PT; Elsawa SF; Sotomayor EM; Gupta M
J Hematol Oncol; 2019 Jul; 12(1):73. PubMed ID: 31288832
[TBL] [Abstract][Full Text] [Related]
36. Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.
Zhu Y; Tchkonia T; Fuhrmann-Stroissnigg H; Dai HM; Ling YY; Stout MB; Pirtskhalava T; Giorgadze N; Johnson KO; Giles CB; Wren JD; Niedernhofer LJ; Robbins PD; Kirkland JL
Aging Cell; 2016 Jun; 15(3):428-35. PubMed ID: 26711051
[TBL] [Abstract][Full Text] [Related]
37. Mitochondrial protection impairs BET bromodomain inhibitor-mediated cell death and provides rationale for combination therapeutic strategies.
Lasorsa E; Smonksey M; Kirk JS; Rosario S; Hernandez-Ilizaliturri FJ; Ellis L
Cell Death Dis; 2015 Dec; 6(12):e2014. PubMed ID: 26658189
[TBL] [Abstract][Full Text] [Related]
38. Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-X
Saleh T; Carpenter VJ; Tyutyunyk-Massey L; Murray G; Leverson JD; Souers AJ; Alotaibi MR; Faber AC; Reed J; Harada H; Gewirtz DA
Mol Oncol; 2020 Oct; 14(10):2504-2519. PubMed ID: 32652830
[TBL] [Abstract][Full Text] [Related]
39. BET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc-induced lymphoma cells.
Muralidharan SV; Bhadury J; Nilsson LM; Green LC; McLure KG; Nilsson JA
Oncogene; 2016 Sep; 35(36):4689-97. PubMed ID: 26804177
[TBL] [Abstract][Full Text] [Related]
40. Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progression.
Liu CY; Huang TT; Chen YT; Chen JL; Chu PY; Huang CT; Wang WL; Lau KY; Dai MS; Shiau CW; Tseng LM
EBioMedicine; 2019 Feb; 40():263-275. PubMed ID: 30651219
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
