These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 30484632)

  • 1. Structural and Metal Ion Effects on Human Topoisomerase IIα Inhibition by α-(N)-Heterocyclic Thiosemicarbazones.
    Morris WH; Ngo L; Wilson JT; Medawala W; Brown AR; Conner JD; Fabunmi F; Cashman DJ; Lisic EC; Yu T; Deweese JE; Jiang X
    Chem Res Toxicol; 2019 Jan; 32(1):90-99. PubMed ID: 30484632
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Clarifying the Mechanism of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα and IIβ.
    Keck JM; Conner JD; Wilson JT; Jiang X; Lisic EC; Deweese JE
    Chem Res Toxicol; 2019 Oct; 32(10):2135-2143. PubMed ID: 31512855
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Examination of the Impact of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα.
    Wilson JT; Jiang X; McGill BC; Lisic EC; Deweese JE
    Chem Res Toxicol; 2016 Apr; 29(4):649-58. PubMed ID: 26982206
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of metalation in the topoisomerase IIα inhibition and antiproliferation activity of a series of α-heterocyclic-N4-substituted thiosemicarbazones and their Cu(II) complexes.
    Zeglis BM; Divilov V; Lewis JS
    J Med Chem; 2011 Apr; 54(7):2391-8. PubMed ID: 21391686
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quinoline-2-carboxaldehyde thiosemicarbazones and their Cu(II) and Ni(II) complexes as topoisomerase IIa inhibitors.
    Bisceglie F; Musiari A; Pinelli S; Alinovi R; Menozzi I; Polverini E; Tarasconi P; Tavone M; Pelosi G
    J Inorg Biochem; 2015 Nov; 152():10-9. PubMed ID: 26335598
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes.
    Jiang X; Fielding LA; Davis H; Carroll W; Lisic EC; Deweese JE
    Int J Mol Sci; 2023 Jul; 24(15):. PubMed ID: 37569386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Copper(II) complexes with highly water-soluble L- and D-proline-thiosemicarbazone conjugates as potential inhibitors of Topoisomerase IIα.
    Bacher F; Enyedy É; Nagy NV; Rockenbauer A; Bognár GM; Trondl R; Novak MS; Klapproth E; Kiss T; Arion VB
    Inorg Chem; 2013 Aug; 52(15):8895-908. PubMed ID: 23829568
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition.
    Ribeiro AG; Almeida SMV; de Oliveira JF; Souza TRCL; Santos KLD; Albuquerque APB; Nogueira MCBL; Carvalho Junior LB; Moura RO; da Silva AC; Pereira VRA; Castro MCAB; Lima MDCA
    Eur J Med Chem; 2019 Nov; 182():111592. PubMed ID: 31421632
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 5-Nitro-Thiophene-Thiosemicarbazone Derivatives Present Antitumor Activity Mediated by Apoptosis and DNA Intercalation.
    Roque Marques KM; do Desterro MR; de Arruda SM; de Araújo Neto LN; do Carmo Alves de Lima M; de Almeida SMV; da Silva ECD; de Aquino TM; da Silva-Júnior EF; de Araújo-Júnior JX; de M Silva M; de A Dantas MD; Santos JCC; Figueiredo IM; Bazin MA; Marchand P; da Silva TG; Mendonça Junior FJB
    Curr Top Med Chem; 2019; 19(13):1075-1091. PubMed ID: 31223089
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, computational quantum chemical study, in silico ADMET and molecular docking analysis, in vitro biological evaluation of a novel sulfur heterocyclic thiophene derivative containing 1,2,3-triazole and pyridine moieties as a potential human topoisomerase IIα inhibiting anticancer agent.
    Murugavel S; Ravikumar C; Jaabil G; Alagusundaram P
    Comput Biol Chem; 2019 Apr; 79():73-82. PubMed ID: 30731361
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 64Cu-azabicyclo[3.2.2]nonane thiosemicarbazone complexes: radiopharmaceuticals for PET of topoisomerase II expression in tumors.
    Wei L; Easmon J; Nagi RK; Muegge BD; Meyer LA; Lewis JS
    J Nucl Med; 2006 Dec; 47(12):2034-41. PubMed ID: 17138747
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anticancer potency of copper(II) complexes of thiosemicarbazones.
    Singh NK; Kumbhar AA; Pokharel YR; Yadav PN
    J Inorg Biochem; 2020 Sep; 210():111134. PubMed ID: 32673842
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism of inhibition of the ATPase domain of human topoisomerase IIα by 1,4-benzoquinone, 1,2-naphthoquinone, 1,4-naphthoquinone, and 9,10-phenanthroquinone.
    Gurbani D; Kukshal V; Laubenthal J; Kumar A; Pandey A; Tripathi S; Arora A; Jain SK; Ramachandran R; Anderson D; Dhawan A
    Toxicol Sci; 2012 Apr; 126(2):372-90. PubMed ID: 22218491
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, Characterization, and in Vitro Anticancer Activity of Copper and Zinc Bis(Thiosemicarbazone) Complexes.
    Anjum R; Palanimuthu D; Kalinowski DS; Lewis W; Park KC; Kovacevic Z; Khan IU; Richardson DR
    Inorg Chem; 2019 Oct; 58(20):13709-13723. PubMed ID: 31339305
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ.
    Oviatt AA; Kuriappan JA; Minniti E; Vann KR; Onuorah P; Minarini A; De Vivo M; Osheroff N
    Bioorg Med Chem Lett; 2018 Sep; 28(17):2961-2968. PubMed ID: 30006062
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reactivity of Cu(ii)-, Zn(ii)- and Fe(ii)-thiosemicarbazone complexes with glutathione and metallothionein: from stability to dissociation to transmetallation.
    Santoro A; Vileno B; Palacios Ò; Peris-Díaz MD; Riegel G; Gaiddon C; Krężel A; Faller P
    Metallomics; 2019 May; 11(5):994-1004. PubMed ID: 31011727
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insight into eukaryotic topoisomerase II-inhibiting fused heterocyclic compounds in human cancer cell lines by molecular docking.
    Taskin T; Yilmaz S; Yildiz I; Yalcin I; Aki E
    SAR QSAR Environ Res; 2012; 23(3-4):345-55. PubMed ID: 22490049
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
    Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Palladium(II) complexes of 2-acetylpyridine N(4)-methyl, N(4)-ethyl and N(4)-phenyl-thiosemicarbazones. Crystal structure of chloro(2-acetylpyridine N(4)-methylthiosemicarbazonato) palladium(II). Synthesis, spectral studies, in vitro and in vivo antitumour activity.
    Kovala-Demertzi D; Domopoulou A; Demertzis MA; Valle G; Papageorgiou A
    J Inorg Biochem; 1997 Nov; 68(2):147-55. PubMed ID: 9336974
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents.
    Chen TC; Wu CL; Lee CC; Chen CL; Yu DS; Huang HS
    Eur J Med Chem; 2015 Oct; 103():615-27. PubMed ID: 25799376
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.