BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

451 related articles for article (PubMed ID: 30484872)

  • 1. Design of Hedgehog pathway inhibitors for cancer treatment.
    Bariwal J; Kumar V; Dong Y; Mahato RI
    Med Res Rev; 2019 May; 39(3):1137-1204. PubMed ID: 30484872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of Hedgehog Antagonists for Cancer Therapy.
    Khatra H; Bose C; Sinha S
    Curr Med Chem; 2017; 24(19):2033-2058. PubMed ID: 28302010
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of [1,2,4]triazolo[4,3-a]pyridines as potent Smoothened inhibitors targeting the Hedgehog pathway with improved antitumor activity in vivo.
    Tian N; Wu H; Zhang H; Yang D; Lv L; Yang Z; Zhang T; Quan D; Zhou L; Xie Y; Xu Y; Wei N; Zhang J; Chen M; Schmitz JC; Tian Y; Wu S
    Bioorg Med Chem; 2020 Aug; 28(16):115584. PubMed ID: 32690258
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers.
    Li QR; Zhao H; Zhang XS; Lang H; Yu K
    Acta Pharmacol Sin; 2019 Feb; 40(2):257-267. PubMed ID: 29777201
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Strategies to target the Hedgehog signaling pathway for cancer therapy.
    Xin M; Ji X; De La Cruz LK; Thareja S; Wang B
    Med Res Rev; 2018 May; 38(3):870-913. PubMed ID: 29315702
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small-molecule inhibitors of the hedgehog signaling pathway as cancer therapeutics.
    Peukert S; Miller-Moslin K
    ChemMedChem; 2010 Apr; 5(4):500-12. PubMed ID: 20229564
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recent patents for Hedgehog pathway inhibitors for the treatment of malignancy.
    Tremblay MR; Nesler M; Weatherhead R; Castro AC
    Expert Opin Ther Pat; 2009 Aug; 19(8):1039-56. PubMed ID: 19505195
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hedgehog Signaling: From Basic Biology to Cancer Therapy.
    Wu F; Zhang Y; Sun B; McMahon AP; Wang Y
    Cell Chem Biol; 2017 Mar; 24(3):252-280. PubMed ID: 28286127
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog pathway inhibitors: a patent review (2009--present).
    Hadden MK
    Expert Opin Ther Pat; 2013 Mar; 23(3):345-61. PubMed ID: 23294277
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic.
    Wang J; Zhang Y; Huang WJ; Yang J; Tang WG; Huang TM; Tan WF
    Acta Pharmacol Sin; 2021 Jun; 42(6):1005-1013. PubMed ID: 32855528
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs.
    Kaboli PJ; Bazrafkan M; Ismail P; Ling KH
    Recent Pat Anticancer Drug Discov; 2017 Nov; 12(4):384-400. PubMed ID: 28969581
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß.
    Kremer L; Hennes E; Brause A; Ursu A; Robke L; Matsubayashi HT; Nihongaki Y; Flegel J; Mejdrová I; Eickhoff J; Baumann M; Nencka R; Janning P; Kordes S; Schöler HR; Sterneckert J; Inoue T; Ziegler S; Waldmann H
    Angew Chem Int Ed Engl; 2019 Nov; 58(46):16617-16628. PubMed ID: 31454140
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent advances in the design of Hedgehog pathway inhibitors for the treatment of malignancies.
    Banerjee U; Hadden MK
    Expert Opin Drug Discov; 2014 Jul; 9(7):751-71. PubMed ID: 24850423
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting Hedgehog signaling and understanding refractory response to treatment with Hedgehog pathway inhibitors.
    Queiroz KC; Spek CA; Peppelenbosch MP
    Drug Resist Updat; 2012 Aug; 15(4):211-22. PubMed ID: 22910179
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies.
    Galperin I; Dempwolff L; Diederich WE; Lauth M
    J Med Chem; 2019 Sep; 62(18):8392-8411. PubMed ID: 30986059
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.
    Manetti F; Petricci E
    Expert Opin Ther Pat; 2016; 26(4):529-35. PubMed ID: 26666870
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold.
    Berardozzi S; Bernardi F; Infante P; Ingallina C; Toscano S; De Paolis E; Alfonsi R; Caimano M; Botta B; Mori M; Di Marcotullio L; Ghirga F
    Eur J Med Chem; 2018 Aug; 156():554-562. PubMed ID: 30025349
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.
    Infante P; Alfonsi R; Ingallina C; Quaglio D; Ghirga F; D'Acquarica I; Bernardi F; Di Magno L; Canettieri G; Screpanti I; Gulino A; Botta B; Mori M; Di Marcotullio L
    Cell Death Dis; 2016 Sep; 7(9):e2376. PubMed ID: 27899820
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hedgehog signaling pathway inhibitors: an updated patent review (2015-present).
    Quaglio D; Infante P; Di Marcotullio L; Botta B; Mori M
    Expert Opin Ther Pat; 2020 Apr; 30(4):235-250. PubMed ID: 32070165
    [No Abstract]   [Full Text] [Related]  

  • 20. The Role of Smoothened in Cancer.
    Jeng KS; Sheen IS; Leu CM; Tseng PH; Chang CF
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32962123
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.