314 related articles for article (PubMed ID: 30488017)
1. The Histone H3 Lysine 4 Presenter WDR5 as an Oncogenic Protein and Novel Epigenetic Target in Cancer.
Lu K; Tao H; Si X; Chen Q
Front Oncol; 2018; 8():502. PubMed ID: 30488017
[TBL] [Abstract][Full Text] [Related]
2. Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Xue H; Yao T; Cao M; Zhu G; Li Y; Yuan G; Chen Y; Lei M; Huang J
Nature; 2019 Sep; 573(7774):445-449. PubMed ID: 31485071
[TBL] [Abstract][Full Text] [Related]
3. Regulation of DNA replication and chromosomal polyploidy by the MLL-WDR5-RBBP5 methyltransferases.
Lu F; Wu X; Yin F; Chia-Fang Lee C; Yu M; Mihaylov IS; Yu J; Sun H; Zhang H
Biol Open; 2016 Oct; 5(10):1449-1460. PubMed ID: 27744293
[TBL] [Abstract][Full Text] [Related]
4. WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma.
Sun Y; Bell JL; Carter D; Gherardi S; Poulos RC; Milazzo G; Wong JW; Al-Awar R; Tee AE; Liu PY; Liu B; Atmadibrata B; Wong M; Trahair T; Zhao Q; Shohet JM; Haupt Y; Schulte JH; Brown PJ; Arrowsmith CH; Vedadi M; MacKenzie KL; Hüttelmaier S; Perini G; Marshall GM; Braithwaite A; Liu T
Cancer Res; 2015 Dec; 75(23):5143-54. PubMed ID: 26471359
[TBL] [Abstract][Full Text] [Related]
5. Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.
Alicea-Velázquez NL; Shinsky SA; Loh DM; Lee JH; Skalnik DG; Cosgrove MS
J Biol Chem; 2016 Oct; 291(43):22357-22372. PubMed ID: 27563068
[TBL] [Abstract][Full Text] [Related]
6. ASH2L-Promoted
Wu YJ; Li LX; Liu L; Zhao SS; Qiu HR; Wang H
Onco Targets Ther; 2020; 13():381-387. PubMed ID: 32021283
[TBL] [Abstract][Full Text] [Related]
7. Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes.
Steward MM; Lee JS; O'Donovan A; Wyatt M; Bernstein BE; Shilatifard A
Nat Struct Mol Biol; 2006 Sep; 13(9):852-4. PubMed ID: 16892064
[TBL] [Abstract][Full Text] [Related]
8. Proton pump inhibitors selectively suppress MLL rearranged leukemia cells via disrupting MLL1-WDR5 protein-protein interaction.
Chen WL; Li DD; Chen X; Wang YZ; Xu JJ; Jiang ZY; You QD; Guo XK
Eur J Med Chem; 2020 Feb; 188():112027. PubMed ID: 31923859
[TBL] [Abstract][Full Text] [Related]
9. Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.
Bochyńska A; Lüscher-Firzlaff J; Lüscher B
Cells; 2018 Mar; 7(3):. PubMed ID: 29498679
[TBL] [Abstract][Full Text] [Related]
10. A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.
Shinsky SA; Hu M; Vought VE; Ng SB; Bamshad MJ; Shendure J; Cosgrove MS
J Mol Biol; 2014 Jun; 426(12):2283-99. PubMed ID: 24680668
[TBL] [Abstract][Full Text] [Related]
11. Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis.
Zhang X; Zheng X; Yang H; Yan J; Fu X; Wei R; Xu X; Zhang Z; Yu A; Zhou K; Ding J; Geng M; Huang X
Cancer Lett; 2018 Sep; 431():150-160. PubMed ID: 29857126
[TBL] [Abstract][Full Text] [Related]
12. The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein- Protein Interaction.
Ye X; Chen G; Jin J; Zhang B; Wang Y; Cai Z; Ye F
Curr Med Chem; 2020; 27(33):5530-5542. PubMed ID: 31132972
[TBL] [Abstract][Full Text] [Related]
13. Targeting WDR5: A WINning Anti-Cancer Strategy?
Aho ER; Weissmiller AM; Fesik SW; Tansey WP
Epigenet Insights; 2019; 12():2516865719865282. PubMed ID: 31360909
[TBL] [Abstract][Full Text] [Related]
14. WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage.
Neilsen BK; Chakraborty B; McCall JL; Frodyma DE; Sleightholm RL; Fisher KW; Lewis RE
BMC Cancer; 2018 Jun; 18(1):673. PubMed ID: 29925347
[TBL] [Abstract][Full Text] [Related]
15. Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.
Shinsky SA; Cosgrove MS
J Biol Chem; 2015 Oct; 290(43):25819-33. PubMed ID: 26324722
[TBL] [Abstract][Full Text] [Related]
16. MLL/WDR5 Complex Regulates Kif2A Localization to Ensure Chromosome Congression and Proper Spindle Assembly during Mitosis.
Ali A; Veeranki SN; Chinchole A; Tyagi S
Dev Cell; 2017 Jun; 41(6):605-622.e7. PubMed ID: 28633016
[TBL] [Abstract][Full Text] [Related]
17. Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction.
Karatas H; Townsend EC; Bernard D; Dou Y; Wang S
J Med Chem; 2010 Jul; 53(14):5179-85. PubMed ID: 20575550
[TBL] [Abstract][Full Text] [Related]
18. Histone H3 lysine 4 methyltransferase KMT2D.
Froimchuk E; Jang Y; Ge K
Gene; 2017 Sep; 627():337-342. PubMed ID: 28669924
[TBL] [Abstract][Full Text] [Related]
19. Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration.
Namitz KEW; Tan S; Cosgrove MS
J Biol Chem; 2023 Feb; 299(2):102874. PubMed ID: 36623730
[TBL] [Abstract][Full Text] [Related]
20. Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers.
Sun J; Zhao Y; McGreal R; Cohen-Tayar Y; Rockowitz S; Wilczek C; Ashery-Padan R; Shechter D; Zheng D; Cvekl A
Epigenetics Chromatin; 2016; 9(1):37. PubMed ID: 27617035
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
