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3. Molecular defects in the insulin receptor in patients with leprechaunism and in their parents. Reddy SS; Muller-Wieland D; Kriauciunas K; Kahn CR J Lab Clin Med; 1989 Aug; 114(2):165-70. PubMed ID: 2569023 [TBL] [Abstract][Full Text] [Related]
4. Structural analysis of normal and mutant insulin receptors in fibroblasts cultured from families with leprechaunism. Endo F; Nagata N; Priest JH; Longo N; Elsas LJ Am J Hum Genet; 1987 Sep; 41(3):402-17. PubMed ID: 3631076 [TBL] [Abstract][Full Text] [Related]
5. Severe resistance to insulin and insulin-like growth factor-I in cells from a patient with leprechaunism as a result of two mutations in the tyrosine kinase domain of the insulin receptor. Desbois-Mouthon C; Danan C; Amselem S; Blivet-Van Eggelpoel MJ; Sert-Langeron C; Goossens M; Besmond C; Capeau J; Caron M Metabolism; 1996 Dec; 45(12):1493-500. PubMed ID: 8969282 [TBL] [Abstract][Full Text] [Related]
6. Insulin receptor tyrosine kinase activity is abnormal in circulating cells and cultured fibroblasts but normal in transformed lymphocytes from a type A insulin-resistant patient. Grunberger G; Comi RJ; Carpentier JL; Podskalny JM; McElduff A; Taylor SI; Gorden P J Lab Clin Med; 1988 Jul; 112(1):122-32. PubMed ID: 3292678 [TBL] [Abstract][Full Text] [Related]
7. Fibroblasts from a leprechaun patient have defects in insulin binding and insulin receptor autophosphorylation. Maassen JA; Klinkhamer MP; van der Zon GC; Sips H; Möller W; Krans HM; Lindhout D; Beemer FA Diabetologia; 1988 Aug; 31(8):612-7. PubMed ID: 2851471 [TBL] [Abstract][Full Text] [Related]
8. Tyrosine-kinase defect of the insulin receptor in cultured fibroblasts from patients with lipoatropic diabetes. Magré J; Grigorescu F; Reynet C; Caron M; Capony JP; White MF; Picard J; Mirouze J; Capeau J J Clin Endocrinol Metab; 1989 Jul; 69(1):142-50. PubMed ID: 2543688 [TBL] [Abstract][Full Text] [Related]
9. Insulin-receptor autophosphorylation and kinase activity are constitutively increased in fibroblasts cultured from a patient with heritable insulin-resistance. Longo N; Shuster RC; Griffin LD; Elsas LJ Biochem Biophys Res Commun; 1990 Mar; 167(3):1229-34. PubMed ID: 2157428 [TBL] [Abstract][Full Text] [Related]
10. A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis. McClain DA; Maegawa H; Lee J; Dull TJ; Ulrich A; Olefsky JM J Biol Chem; 1987 Oct; 262(30):14663-71. PubMed ID: 3312193 [TBL] [Abstract][Full Text] [Related]
11. Alterations in the hepatic insulin receptor kinase in genetic and acquired obesity in rats. Hurrell DG; Pedersen O; Kahn CR Endocrinology; 1989 Nov; 125(5):2454-62. PubMed ID: 2551653 [TBL] [Abstract][Full Text] [Related]
12. Defects in insulin binding and autophosphorylation of erythrocyte insulin receptors in patients with syndromes of severe insulin resistance and their parents. Grigorescu F; Herzberg V; King G; Meistas M; Elders J; Frazer T; Kahn CR J Clin Endocrinol Metab; 1987 Mar; 64(3):549-56. PubMed ID: 3029156 [TBL] [Abstract][Full Text] [Related]
13. Decreased insulin receptor (IR) autophosphorylation in fibroblasts from patients with PCOS: effects of serine kinase inhibitors and IR activators. Li M; Youngren JF; Dunaif A; Goldfine ID; Maddux BA; Zhang BB; Evans JL J Clin Endocrinol Metab; 2002 Sep; 87(9):4088-93. PubMed ID: 12213853 [TBL] [Abstract][Full Text] [Related]
15. Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation. Mastick CC; Kato H; Roberts CT; LeRoith D; Saltiel AR Endocrinology; 1994 Jul; 135(1):214-22. PubMed ID: 7516864 [TBL] [Abstract][Full Text] [Related]
16. Deletion of the insulin receptor beta-subunit acidic domain results in enhanced metabolic signaling. Rolband GC; Williams JF; Webster NJ; Olefsky JM Endocrinology; 1993 Sep; 133(3):1437-43. PubMed ID: 8396020 [TBL] [Abstract][Full Text] [Related]
17. Deletion of 3 basepairs resulting in the loss of lysine-121 in the insulin receptor alpha-subunit in a patient with leprechaunism: binding, phosphorylation, and biological activity. Jospe N; Zhu J; Liu R; Livingston JN; Furlanetto RW J Clin Endocrinol Metab; 1994 Nov; 79(5):1294-302. PubMed ID: 7962321 [TBL] [Abstract][Full Text] [Related]
18. Hybrid formation between endogenous mouse and transfected human tyrosine kinase-deficient (A/K1018) insulin receptors leads to decreased insulin sensitivity in 3T3-L1 adipocytes. Grako KA; McClain DA; Olefsky JM Mol Endocrinol; 1994 Jun; 8(6):682-92. PubMed ID: 7935484 [TBL] [Abstract][Full Text] [Related]
19. Defective insulin receptor function in down-regulated HepG2 cells. Williams JF; Olefsky JM Endocrinology; 1990 Oct; 127(4):1706-17. PubMed ID: 2169397 [TBL] [Abstract][Full Text] [Related]
20. A mutation in the tyrosine kinase domain of the insulin receptor associated with insulin resistance in an obese woman. Cama A; de la Luz Sierra M; Ottini L; Kadowaki T; Gorden P; Imperato-McGinley J; Taylor SI J Clin Endocrinol Metab; 1991 Oct; 73(4):894-901. PubMed ID: 1890161 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]