187 related articles for article (PubMed ID: 30497261)
1. Comprehensive 3D-QSAR Model Predicts Binding Affinity of Structurally Diverse Sigma 1 Receptor Ligands.
Peng Y; Dong H; Welsh WJ
J Chem Inf Model; 2019 Jan; 59(1):486-497. PubMed ID: 30497261
[TBL] [Abstract][Full Text] [Related]
2. QSAR-Based Computational Approaches to Accelerate the Discovery of Sigma-2 Receptor (S2R) Ligands as Therapeutic Drugs.
Yu Y; Dong H; Peng Y; Welsh WJ
Molecules; 2021 Aug; 26(17):. PubMed ID: 34500703
[TBL] [Abstract][Full Text] [Related]
3. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis.
Rescifina A; Floresta G; Marrazzo A; Parenti C; Prezzavento O; Nastasi G; Dichiara M; Amata E
Eur J Pharm Sci; 2017 Aug; 106():94-101. PubMed ID: 28571781
[TBL] [Abstract][Full Text] [Related]
4. New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative.
Rossino G; Orellana I; Caballero J; Schepmann D; Wünsch B; Rui M; Rossi D; González-Avendaño M; Collina S; Vergara-Jaque A
J Chem Inf Model; 2020 Feb; 60(2):756-765. PubMed ID: 31809025
[TBL] [Abstract][Full Text] [Related]
5. Novel High Affinity Sigma-1 Receptor Ligands from Minimal Ensemble Docking-Based Virtual Screening.
Dvorácskó S; Lázár L; Fülöp F; Palkó M; Zalán Z; Penke B; Fülöp L; Tömböly C; Bogár F
Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360878
[TBL] [Abstract][Full Text] [Related]
6. Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines.
Rossi D; Rui M; Di Giacomo M; Schepmann D; Wünsch B; Monteleone S; Liedl KR; Collina S
Bioorg Med Chem; 2017 Jan; 25(1):11-19. PubMed ID: 27838169
[TBL] [Abstract][Full Text] [Related]
7. A systematic exploration of the effects of flexibility and basicity on sigma (σ) receptor binding in a series of substituted diamines.
Conroy T; Manohar M; Gong Y; Wilkinson SM; Webster M; Lieberman BP; Banister SD; Reekie TA; Mach RH; Rendina LM; Kassiou M
Org Biomol Chem; 2016 Oct; 14(39):9388-9405. PubMed ID: 27714195
[TBL] [Abstract][Full Text] [Related]
8. The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands.
Mishra AK; Mavlyutov T; Singh DR; Biener G; Yang J; Oliver JA; Ruoho A; Raicu V
Biochem J; 2015 Mar; 466(2):263-271. PubMed ID: 25510962
[TBL] [Abstract][Full Text] [Related]
9. Novel Sigma 1 Receptor Antagonists as Potential Therapeutics for Pain Management.
Peng Y; Zhang Q; Welsh WJ
J Med Chem; 2021 Jan; 64(1):890-904. PubMed ID: 33372782
[TBL] [Abstract][Full Text] [Related]
10. 5D-QSAR for spirocyclic sigma1 receptor ligands by Quasar receptor surface modeling.
Oberdorf C; Schmidt TJ; Wünsch B
Eur J Med Chem; 2010 Jul; 45(7):3116-24. PubMed ID: 20427100
[TBL] [Abstract][Full Text] [Related]
11. A comprehensive ligand based mapping of the σ₂ receptor binding pocket.
Rhoades DJ; Kinder DH; Mahfouz TM
Med Chem; 2014; 10(1):98-121. PubMed ID: 23521001
[TBL] [Abstract][Full Text] [Related]
12. Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands.
Elkholy N; Abdelwaly A; Mohamed K; Amata E; Lombino J; Cosentino G; Intagliata S; Helal MA
Chem Biol Drug Des; 2022 Jul; 100(1):25-40. PubMed ID: 35353926
[TBL] [Abstract][Full Text] [Related]
13. 3D-QSAR comparative molecular field analysis on opioid receptor antagonists: pooling data from different studies.
Peng Y; Keenan SM; Zhang Q; Kholodovych V; Welsh WJ
J Med Chem; 2005 Mar; 48(5):1620-9. PubMed ID: 15743203
[TBL] [Abstract][Full Text] [Related]
14. Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands.
Floresta G; Rescifina A; Marrazzo A; Dichiara M; Pistarà V; Pittalà V; Prezzavento O; Amata E
Eur J Med Chem; 2017 Oct; 139():884-891. PubMed ID: 28866257
[TBL] [Abstract][Full Text] [Related]
15. The oligomeric states of the purified sigma-1 receptor are stabilized by ligands.
Gromek KA; Suchy FP; Meddaugh HR; Wrobel RL; LaPointe LM; Chu UB; Primm JG; Ruoho AE; Senes A; Fox BG
J Biol Chem; 2014 Jul; 289(29):20333-44. PubMed ID: 24847081
[TBL] [Abstract][Full Text] [Related]
16. Docking, Interaction Fingerprint, and Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) of Sigma1 Receptor Ligands, Analogs of the Neuroprotective Agent RC-33.
Velázquez-Libera JL; Rossino G; Navarro-Retamal C; Collina S; Caballero J
Front Chem; 2019; 7():496. PubMed ID: 31355187
[TBL] [Abstract][Full Text] [Related]
17. Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.
Laggner C; Schieferer C; Fiechtner B; Poles G; Hoffmann RD; Glossmann H; Langer T; Moebius FF
J Med Chem; 2005 Jul; 48(15):4754-64. PubMed ID: 16033255
[TBL] [Abstract][Full Text] [Related]
18. Advances with the discovery and development of novel sigma 1 receptor antagonists for the management of pain.
Burns M; Guadagnoli N; McCurdy CR
Expert Opin Drug Discov; 2023 Jul; 18(7):693-705. PubMed ID: 37203187
[TBL] [Abstract][Full Text] [Related]
19. Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization.
Rossino G; Rui M; Linciano P; Rossi D; Boiocchi M; Peviani M; Poggio E; Curti D; Schepmann D; Wünsch B; González-Avendaño M; Vergara-Jaque A; Caballero J; Collina S
J Med Chem; 2021 Oct; 64(20):14997-15016. PubMed ID: 34624193
[TBL] [Abstract][Full Text] [Related]
20. Structure-Based Modeling of Sigma 1 Receptor Interactions with Ligands and Cholesterol and Implications for Its Biological Function.
Kim M; Bezprozvanny I
Int J Mol Sci; 2023 Aug; 24(16):. PubMed ID: 37629160
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
