BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 30499081)

  • 1. Recombinant Antibody Production in CHO and NS0 Cells: Differences and Similarities.
    Dhara VG; Naik HM; Majewska NI; Betenbaugh MJ
    BioDrugs; 2018 Dec; 32(6):571-584. PubMed ID: 30499081
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Generation of a cholesterol-independent, non-GS NS0 cell line through chemical treatment and application for high titer antibody production.
    Li J; Gu W; Edmondson DG; Lu C; Vijayasankaran N; Figueroa B; Stevenson D; Ryll T; Li F
    Biotechnol Bioeng; 2012 Jul; 109(7):1685-92. PubMed ID: 22252532
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Superfluous glutamine synthetase activity in Chinese Hamster Ovary cells selected under glutamine limitation is growth limiting in glutamine-replete conditions and can be inhibited by serine.
    Maralingannavar V; Parmar D; Panchagnula V; Gadgil M
    Biotechnol Prog; 2019 Sep; 35(5):e2856. PubMed ID: 31148368
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reduction of ammonia and lactate through the coupling of glutamine synthetase selection and downregulation of lactate dehydrogenase-A in CHO cells.
    Noh SM; Park JH; Lim MS; Kim JW; Lee GM
    Appl Microbiol Biotechnol; 2017 Feb; 101(3):1035-1045. PubMed ID: 27704181
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism.
    Ma N; Ellet J; Okediadi C; Hermes P; McCormick E; Casnocha S
    Biotechnol Prog; 2009; 25(5):1353-63. PubMed ID: 19637321
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Derivation and characterization of cholesterol-independent non-GS NS0 cell lines for production of recombinant antibodies.
    Hartman TE; Sar N; Genereux K; Barritt DS; He Y; Burky JE; Wesson MC; Tso JY; Tsurushita N; Zhou W; Sauer PW
    Biotechnol Bioeng; 2007 Feb; 96(2):294-306. PubMed ID: 16897745
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.
    Fan L; Kadura I; Krebs LE; Hatfield CC; Shaw MM; Frye CC
    Biotechnol Bioeng; 2012 Apr; 109(4):1007-15. PubMed ID: 22068567
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Optimization of cell line development in the GS-CHO expression system using a high-throughput, single cell-based clone selection system.
    Nakamura T; Omasa T
    J Biosci Bioeng; 2015 Sep; 120(3):323-9. PubMed ID: 25792187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of glutamine and asparagine on recombinant antibody production using CHO-GS cell lines.
    Xu P; Dai XP; Graf E; Martel R; Russell R
    Biotechnol Prog; 2014; 30(6):1457-68. PubMed ID: 25079388
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics.
    Lin PC; Chan KF; Kiess IA; Tan J; Shahreel W; Wong SY; Song Z
    MAbs; 2019 Jul; 11(5):965-976. PubMed ID: 31043114
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Control of amino acid transport into Chinese hamster ovary cells.
    Geoghegan D; Arnall C; Hatton D; Noble-Longster J; Sellick C; Senussi T; James DC
    Biotechnol Bioeng; 2018 Dec; 115(12):2908-2929. PubMed ID: 29987891
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell.
    Hu Z; Guo D; Yip SS; Zhan D; Misaghi S; Joly JC; Snedecor BR; Shen AY
    Biotechnol Prog; 2013; 29(4):980-5. PubMed ID: 23606666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A high cell density transient transfection system for therapeutic protein expression based on a CHO GS-knockout cell line: process development and product quality assessment.
    Rajendra Y; Hougland MD; Alam R; Morehead TA; Barnard GC
    Biotechnol Bioeng; 2015 May; 112(5):977-86. PubMed ID: 25502369
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of a highly-efficient CHO cell line generation system with engineered SV40E promoter.
    Fan L; Kadura I; Krebs LE; Larson JL; Bowden DM; Frye CC
    J Biotechnol; 2013 Dec; 168(4):652-8. PubMed ID: 23994266
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic control of recombinant protein N-glycan processing in NS0 and CHO cells.
    Baker KN; Rendall MH; Hills AE; Hoare M; Freedman RB; James DC
    Biotechnol Bioeng; 2001 May; 73(3):188-202. PubMed ID: 11257601
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methionine sulfoximine supplementation enhances productivity in GS-CHOK1SV cell lines through glutathione biosynthesis.
    Feary M; Racher AJ; Young RJ; Smales CM
    Biotechnol Prog; 2017 Jan; 33(1):17-25. PubMed ID: 27689785
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tetrahydrofolate increases suspension growth of dihydrofolate reductase-deficient chinese hamster ovary DG44 cells in chemically defined media.
    Kim BG; Park HW
    Biotechnol Prog; 2016 Nov; 32(6):1539-1546. PubMed ID: 27578320
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins.
    Dorai H; Corisdeo S; Ellis D; Kinney C; Chomo M; Hawley-Nelson P; Moore G; Betenbaugh MJ; Ganguly S
    Biotechnol Bioeng; 2012 Apr; 109(4):1016-30. PubMed ID: 22068683
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Strategic feeding of NS0 and CHO cell cultures to control glycan profiles and immunogenic epitopes of monoclonal antibodies.
    Villacrés C; Tayi VS; Butler M
    J Biotechnol; 2021 Jun; 333():49-62. PubMed ID: 33901620
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A high-yielding CHO transient system: coexpression of genes encoding EBNA-1 and GS enhances transient protein expression.
    Daramola O; Stevenson J; Dean G; Hatton D; Pettman G; Holmes W; Field R
    Biotechnol Prog; 2014; 30(1):132-41. PubMed ID: 24106171
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.