480 related articles for article (PubMed ID: 30502498)
1. Targeting the proteostasis network in Huntington's disease.
Soares TR; Reis SD; Pinho BR; Duchen MR; Oliveira JMA
Ageing Res Rev; 2019 Jan; 49():92-103. PubMed ID: 30502498
[TBL] [Abstract][Full Text] [Related]
2. Proteostasis of Huntingtin in Health and Disease.
Koyuncu S; Fatima A; Gutierrez-Garcia R; Vilchez D
Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28753941
[TBL] [Abstract][Full Text] [Related]
3. Mn(II) Quinoline Complex (4QMn) Restores Proteostasis and Reduces Toxicity in Experimental Models of Huntington's Disease.
Merino M; Sequedo MD; Sánchez-Sánchez AV; Clares MP; García-España E; Vázquez-Manrique RP; Mullor JL
Int J Mol Sci; 2022 Aug; 23(16):. PubMed ID: 36012207
[TBL] [Abstract][Full Text] [Related]
4. Juvenile Huntington's Disease Skin Fibroblasts Respond with Elevated Parkin Level and Increased Proteasome Activity as a Potential Mechanism to Counterbalance the Pathological Consequences of Mutant Huntingtin Protein.
Aladdin A; Király R; Boto P; Regdon Z; Tar K
Int J Mol Sci; 2019 Oct; 20(21):. PubMed ID: 31717806
[TBL] [Abstract][Full Text] [Related]
5. Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease.
Zhou X; Li G; Kaplan A; Gaschler MM; Zhang X; Hou Z; Jiang M; Zott R; Cremers S; Stockwell BR; Duan W
Hum Mol Genet; 2018 May; 27(9):1545-1555. PubMed ID: 29462355
[TBL] [Abstract][Full Text] [Related]
6. Pramipexole reduces soluble mutant huntingtin and protects striatal neurons through dopamine D3 receptors in a genetic model of Huntington's disease.
Luis-Ravelo D; Estévez-Silva H; Barroso-Chinea P; Afonso-Oramas D; Salas-Hernández J; Rodríguez-Núñez J; Acevedo-Arozena A; Marcellino D; González-Hernández T
Exp Neurol; 2018 Jan; 299(Pt A):137-147. PubMed ID: 29056363
[TBL] [Abstract][Full Text] [Related]
7. Herp Promotes Degradation of Mutant Huntingtin: Involvement of the Proteasome and Molecular Chaperones.
Luo H; Cao L; Liang X; Du A; Peng T; Li H
Mol Neurobiol; 2018 Oct; 55(10):7652-7668. PubMed ID: 29430620
[TBL] [Abstract][Full Text] [Related]
8. Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ; Zhang YY; Fu YH; Zhang H; Li HX; Li QF; Li HL; Tan RK; Jiang CX; Jiang W; Li ZX; Luo C; Lu BX; Dang YJ
Acta Pharmacol Sin; 2021 Oct; 42(10):1556-1566. PubMed ID: 33495516
[TBL] [Abstract][Full Text] [Related]
9. Mitochondrial dynamics and quality control in Huntington's disease.
Guedes-Dias P; Pinho BR; Soares TR; de Proença J; Duchen MR; Oliveira JM
Neurobiol Dis; 2016 Jun; 90():51-7. PubMed ID: 26388396
[TBL] [Abstract][Full Text] [Related]
10. Modulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders.
Reis SD; Pinho BR; Oliveira JMA
Mol Neurobiol; 2017 Oct; 54(8):5829-5854. PubMed ID: 27660272
[TBL] [Abstract][Full Text] [Related]
11. Mutant huntingtin disrupts mitochondrial proteostasis by interacting with TIM23.
Yablonska S; Ganesan V; Ferrando LM; Kim J; Pyzel A; Baranova OV; Khattar NK; Larkin TM; Baranov SV; Chen N; Strohlein CE; Stevens DA; Wang X; Chang YF; Schurdak ME; Carlisle DL; Minden JS; Friedlander RM
Proc Natl Acad Sci U S A; 2019 Aug; 116(33):16593-16602. PubMed ID: 31346086
[TBL] [Abstract][Full Text] [Related]
12. Neural stem cells derived from the developing forebrain of YAC128 mice exhibit pathological features of Huntington's disease.
Li E; Park HR; Hong CP; Kim Y; Choi J; Lee S; Park HJ; Lee B; Kim TA; Kim SJ; Kim HS; Song J
Cell Prolif; 2020 Oct; 53(10):e12893. PubMed ID: 32865873
[TBL] [Abstract][Full Text] [Related]
13. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.
Koyuncu S; Saez I; Lee HJ; Gutierrez-Garcia R; Pokrzywa W; Fatima A; Hoppe T; Vilchez D
Nat Commun; 2018 Jul; 9(1):2886. PubMed ID: 30038412
[TBL] [Abstract][Full Text] [Related]
14. A toxic mutant huntingtin species is resistant to selective autophagy.
Fu Y; Wu P; Pan Y; Sun X; Yang H; Difiglia M; Lu B
Nat Chem Biol; 2017 Nov; 13(11):1152-1154. PubMed ID: 28869595
[TBL] [Abstract][Full Text] [Related]
15. Aptamer Reduces Aggregation of Mutant Huntingtin and Rescues Proteostasis Network in Non-Neuronal and Neuronal Cells.
Jain S; Roy I
ACS Chem Neurosci; 2023 Jun; 14(12):2385-2395. PubMed ID: 37294284
[TBL] [Abstract][Full Text] [Related]
16. Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.
Zhao T; Hong Y; Li S; Li XJ
J Neurosci; 2016 Aug; 36(32):8317-28. PubMed ID: 27511006
[TBL] [Abstract][Full Text] [Related]
17. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.
Ciechanover A; Kwon YT
Exp Mol Med; 2015 Mar; 47(3):e147. PubMed ID: 25766616
[TBL] [Abstract][Full Text] [Related]
18. Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities.
Harding RJ; Tong YF
Acta Pharmacol Sin; 2018 May; 39(5):754-769. PubMed ID: 29620053
[TBL] [Abstract][Full Text] [Related]
19. Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease.
Ehrnhoefer DE; Martin DDO; Schmidt ME; Qiu X; Ladha S; Caron NS; Skotte NH; Nguyen YTN; Vaid K; Southwell AL; Engemann S; Franciosi S; Hayden MR
Acta Neuropathol Commun; 2018 Mar; 6(1):16. PubMed ID: 29510748
[TBL] [Abstract][Full Text] [Related]
20. Mitophagy in Huntington's disease.
Šonský I; Vodička P; Vodičková Kepková K; Hansíková H
Neurochem Int; 2021 Oct; 149():105147. PubMed ID: 34329735
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]