These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
11. Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals. Bhaumik S; Sekar TV; Depuy J; Klimash J; Paulmurugan R Gene Ther; 2012 Mar; 19(3):295-302. PubMed ID: 21753794 [TBL] [Abstract][Full Text] [Related]
12. Prodrugs in Cancer Chemotherapy. Knox RJ; Connors TA Pathol Oncol Res; 1997; 3(4):309-324. PubMed ID: 11173653 [TBL] [Abstract][Full Text] [Related]
13. Targeted prodrug design to optimize drug delivery. Han HK; Amidon GL AAPS PharmSci; 2000; 2(1):E6. PubMed ID: 11741222 [TBL] [Abstract][Full Text] [Related]
14. Prodrugs for targeted tumor therapies: recent developments in ADEPT, GDEPT and PMT. Tietze LF; Schmuck K Curr Pharm Des; 2011; 17(32):3527-47. PubMed ID: 22074425 [TBL] [Abstract][Full Text] [Related]
15. Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form. Johansson E; Parkinson GN; Denny WA; Neidle S J Med Chem; 2003 Sep; 46(19):4009-20. PubMed ID: 12954054 [TBL] [Abstract][Full Text] [Related]
16. Painting the target around the arrow: two-step prodrug therapies from a carbohydrate chemist's perspective. Houston TA Curr Drug Deliv; 2007 Oct; 4(4):264-8. PubMed ID: 17979645 [TBL] [Abstract][Full Text] [Related]
17. Antibody-directed enzyme prodrug therapy (ADEPT) with mustard prodrugs. Springer CJ; Niculescu-Duvaz I Anticancer Drug Des; 1995 Jul; 10(5):361-72. PubMed ID: 7639927 [TBL] [Abstract][Full Text] [Related]
18. Activation of oxazaphosphorines by cytochrome P450: application to gene-directed enzyme prodrug therapy for cancer. Roy P; Waxman DJ Toxicol In Vitro; 2006 Mar; 20(2):176-86. PubMed ID: 16293390 [TBL] [Abstract][Full Text] [Related]
19. Chimeric TNT-3/human beta-glucuronidase fusion proteins for antibody-directed enzyme prodrug therapy (ADEPT). Biela BH; Khawli LA; Hu P; Epstein AL Cancer Biother Radiopharm; 2003 Jun; 18(3):339-53. PubMed ID: 12954121 [TBL] [Abstract][Full Text] [Related]
20. Prodrugs: a challenge for the drug development. Zawilska JB; Wojcieszak J; Olejniczak AB Pharmacol Rep; 2013; 65(1):1-14. PubMed ID: 23563019 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]