BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 30506956)

  • 1. Photoactivated Colibactin Probes Induce Cellular DNA Damage.
    Moodie LWK; Hubert M; Zhou X; Albers MF; Lundmark R; Wanrooij S; Hedberg C
    Angew Chem Int Ed Engl; 2019 Jan; 58(5):1417-1421. PubMed ID: 30506956
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells.
    Bossuet-Greif N; Vignard J; Taieb F; Mirey G; Dubois D; Petit C; Oswald E; Nougayrède JP
    mBio; 2018 Mar; 9(2):. PubMed ID: 29559578
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Colibactin: More Than a New Bacterial Toxin.
    Faïs T; Delmas J; Barnich N; Bonnet R; Dalmasso G
    Toxins (Basel); 2018 Apr; 10(4):. PubMed ID: 29642622
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isolation of a metabolite from the pks island provides insights into colibactin biosynthesis and activity.
    Brotherton CA; Wilson M; Byrd G; Balskus EP
    Org Lett; 2015 Mar; 17(6):1545-8. PubMed ID: 25753745
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Depurination of Colibactin-Derived Interstrand Cross-Links.
    Xue M; Wernke KM; Herzon SB
    Biochemistry; 2020 Feb; 59(7):892-900. PubMed ID: 31977191
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The human gut bacterial genotoxin colibactin alkylates DNA.
    Wilson MR; Jiang Y; Villalta PW; Stornetta A; Boudreau PD; Carrá A; Brennan CA; Chun E; Ngo L; Samson LD; Engelward BP; Garrett WS; Balbo S; Balskus EP
    Science; 2019 Feb; 363(6428):. PubMed ID: 30765538
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance.
    Tripathi P; Shine EE; Healy AR; Kim CS; Herzon SB; Bruner SD; Crawford JM
    J Am Chem Soc; 2017 Dec; 139(49):17719-17722. PubMed ID: 29112397
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure and bioactivity of colibactin.
    Wernke KM; Xue M; Tirla A; Kim CS; Crawford JM; Herzon SB
    Bioorg Med Chem Lett; 2020 Aug; 30(15):127280. PubMed ID: 32527463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage.
    Li ZR; Li J; Cai W; Lai JYH; McKinnie SMK; Zhang WP; Moore BS; Zhang W; Qian PY
    Nat Chem; 2019 Oct; 11(10):880-889. PubMed ID: 31527851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Polyamine Spermidine Modulates the Production of the Bacterial Genotoxin Colibactin.
    Chagneau CV; Garcie C; Bossuet-Greif N; Tronnet S; Brachmann AO; Piel J; Nougayrède JP; Martin P; Oswald E
    mSphere; 2019 Oct; 4(5):. PubMed ID: 31578245
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strains.
    Oliero M; Calvé A; Fragoso G; Cuisiniere T; Hajjar R; Dobrindt U; Santos MM
    BMC Cancer; 2021 Feb; 21(1):172. PubMed ID: 33596864
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A prodrug resistance mechanism is involved in colibactin biosynthesis and cytotoxicity.
    Brotherton CA; Balskus EP
    J Am Chem Soc; 2013 Mar; 135(9):3359-62. PubMed ID: 23406518
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Escherichia coli ClbS is a colibactin resistance protein.
    Bossuet-Greif N; Dubois D; Petit C; Tronnet S; Martin P; Bonnet R; Oswald E; Nougayrède JP
    Mol Microbiol; 2016 Mar; 99(5):897-908. PubMed ID: 26560421
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Probing Microbiome Genotoxicity: A Stable Colibactin Provides Insight into Structure-Activity Relationships and Facilitates Mechanism of Action Studies.
    Wernke KM; Tirla A; Xue M; Surovtseva YV; Menges FS; Herzon SB
    J Am Chem Soc; 2021 Sep; 143(38):15824-15833. PubMed ID: 34524796
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Colibactin: understanding an elusive gut bacterial genotoxin.
    Balskus EP
    Nat Prod Rep; 2015 Nov; 32(11):1534-40. PubMed ID: 26390983
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria.
    Cougnoux A; Delmas J; Gibold L; Faïs T; Romagnoli C; Robin F; Cuevas-Ramos G; Oswald E; Darfeuille-Michaud A; Prati F; Dalmasso G; Bonnet R
    Gut; 2016 Feb; 65(2):278-85. PubMed ID: 25588406
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Model Colibactins Exhibit Human Cell Genotoxicity in the Absence of Host Bacteria.
    Shine EE; Xue M; Patel JR; Healy AR; Surovtseva YV; Herzon SB; Crawford JM
    ACS Chem Biol; 2018 Dec; 13(12):3286-3293. PubMed ID: 30403848
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The bacterial genotoxin colibactin promotes colon tumor growth by modifying the tumor microenvironment.
    Dalmasso G; Cougnoux A; Delmas J; Darfeuille-Michaud A; Bonnet R
    Gut Microbes; 2014; 5(5):675-80. PubMed ID: 25483338
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways.
    Engel P; Vizcaino MI; Crawford JM
    Appl Environ Microbiol; 2015 Feb; 81(4):1502-12. PubMed ID: 25527542
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure elucidation of colibactin and its DNA cross-links.
    Xue M; Kim CS; Healy AR; Wernke KM; Wang Z; Frischling MC; Shine EE; Wang W; Herzon SB; Crawford JM
    Science; 2019 Sep; 365(6457):. PubMed ID: 31395743
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.