These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform. Ibrahim HS; Allam HA; Mahmoud WR; Bonardi A; Nocentini A; Gratteri P; Ibrahim ES; Abdel-Aziz HA; Supuran CT Eur J Med Chem; 2018 May; 152():1-9. PubMed ID: 29684705 [TBL] [Abstract][Full Text] [Related]
6. Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX. Allam HA; Fahim SH; F Abo-Ashour M; Nocentini A; Elbakry ME; Abdelrahman MA; Eldehna WM; Ibrahim HS; Supuran CT Eur J Med Chem; 2019 Oct; 179():547-556. PubMed ID: 31276899 [TBL] [Abstract][Full Text] [Related]
8. Carbonic anhydrase inhibitors. Synthesis of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives and their inhibition of the human cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII. Sławiński J; Szafrański K; Vullo D; Supuran CT Eur J Med Chem; 2013 Nov; 69():701-10. PubMed ID: 24095761 [TBL] [Abstract][Full Text] [Related]
9. Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors. Yamali C; Gul HI; Ece A; Bua S; Angeli A; Sakagami H; Sahin E; Supuran CT Bioorg Chem; 2019 Nov; 92():103222. PubMed ID: 31499260 [TBL] [Abstract][Full Text] [Related]
10. Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes. Gul HI; Yamali C; Bulbuller M; Kirmizibayrak PB; Gul M; Angeli A; Bua S; Supuran CT Bioorg Chem; 2018 Aug; 78():290-297. PubMed ID: 29621641 [TBL] [Abstract][Full Text] [Related]
11. Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds. Abdel-Aziz AA; El-Azab AS; Ceruso M; Supuran CT Bioorg Med Chem Lett; 2014 Nov; 24(22):5185-9. PubMed ID: 25442309 [TBL] [Abstract][Full Text] [Related]
12. Synthesis and inhibition potency of novel ureido benzenesulfonamides incorporating GABA as tumor-associated carbonic anhydrase IX and XII inhibitors. Ceruso M; Antel S; Scozzafava A; Supuran CT J Enzyme Inhib Med Chem; 2016; 31(2):205-11. PubMed ID: 25792500 [TBL] [Abstract][Full Text] [Related]
13. Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines. Abdel Gawad NM; Amin NH; Elsaadi MT; Mohamed FMM; Angeli A; De Luca V; Capasso C; Supuran CT Bioorg Med Chem; 2016 Jul; 24(13):3043-3051. PubMed ID: 27234893 [TBL] [Abstract][Full Text] [Related]
14. Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII. Żołnowska B; Sławiński J; Pogorzelska A; Chojnacki J; Vullo D; Supuran CT Eur J Med Chem; 2014 Jan; 71():135-47. PubMed ID: 24291567 [TBL] [Abstract][Full Text] [Related]
15. Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives. Awadallah FM; El-Waei TA; Hanna MM; Abbas SE; Ceruso M; Oz BE; Guler OO; Supuran CT Eur J Med Chem; 2015; 96():425-35. PubMed ID: 25912674 [TBL] [Abstract][Full Text] [Related]
16. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties. Garaj V; Puccetti L; Fasolis G; Winum JY; Montero JL; Scozzafava A; Vullo D; Innocenti A; Supuran CT Bioorg Med Chem Lett; 2004 Nov; 14(21):5427-33. PubMed ID: 15454239 [TBL] [Abstract][Full Text] [Related]
17. 3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights. Abo-Ashour MF; Eldehna WM; Nocentini A; Bonardi A; Bua S; Ibrahim HS; Elaasser MM; Kryštof V; Jorda R; Gratteri P; Abou-Seri SM; Supuran CT Eur J Med Chem; 2019 Dec; 184():111768. PubMed ID: 31629164 [TBL] [Abstract][Full Text] [Related]
18. Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety. Sethi KK; Vullo D; Verma SM; Tanç M; Carta F; Supuran CT Bioorg Med Chem; 2013 Oct; 21(19):5973-82. PubMed ID: 23965175 [TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of cyclic imides incorporating benzenesulfonamide moieties as carbonic anhydrase I, II, IV and IX inhibitors. Abdel-Aziz AA; Angeli A; El-Azab AS; Abu El-Enin MA; Supuran CT Bioorg Med Chem; 2017 Mar; 25(5):1666-1671. PubMed ID: 28161252 [TBL] [Abstract][Full Text] [Related]