BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 30514904)

  • 21. Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.
    Shi H; Chapman NM; Wen J; Guy C; Long L; Dhungana Y; Rankin S; Pelletier S; Vogel P; Wang H; Peng J; Guan KL; Chi H
    Immunity; 2019 Dec; 51(6):1012-1027.e7. PubMed ID: 31668641
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Rheb/mTORC1 signaling promotes kidney fibroblast activation and fibrosis.
    Jiang L; Xu L; Mao J; Li J; Fang L; Zhou Y; Liu W; He W; Zhao AZ; Yang J; Dai C
    J Am Soc Nephrol; 2013 Jun; 24(7):1114-26. PubMed ID: 23661807
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Persistent Rheb-induced mTORC1 activation in spinal cord neurons induces hypersensitivity in neuropathic pain.
    Ma X; Du W; Wang W; Luo L; Huang M; Wang H; Lin R; Li Z; Shi H; Yuan T; Jiang W; Worley PF; Xu T
    Cell Death Dis; 2020 Sep; 11(9):747. PubMed ID: 32920594
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase.
    Emmanuel N; Ragunathan S; Shan Q; Wang F; Giannakou A; Huser N; Jin G; Myers J; Abraham RT; Unsal-Kacmaz K
    Cell Rep; 2017 Jun; 19(13):2665-2680. PubMed ID: 28658616
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.
    Mahoney SJ; Narayan S; Molz L; Berstler LA; Kang SA; Vlasuk GP; Saiah E
    Nat Commun; 2018 Feb; 9(1):548. PubMed ID: 29416044
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Design of negative-regulating proteins of Rheb/mTORC1 with much-reduced sizes of the tuberous sclerosis protein complex.
    Fu W; Wu G
    Protein Sci; 2023 Aug; 32(8):e4731. PubMed ID: 37462942
    [TBL] [Abstract][Full Text] [Related]  

  • 27. NMR analysis of the backbone dynamics of the small GTPase Rheb and its interaction with the regulatory protein FKBP38.
    De Cicco M; Kiss L; Dames SA
    FEBS Lett; 2018 Jan; 592(1):130-146. PubMed ID: 29194576
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
    Yang H; Jiang X; Li B; Yang HJ; Miller M; Yang A; Dhar A; Pavletich NP
    Nature; 2017 Dec; 552(7685):368-373. PubMed ID: 29236692
    [TBL] [Abstract][Full Text] [Related]  

  • 29. E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression.
    Wang D; Xu C; Yang W; Chen J; Ou Y; Guan Y; Guan J; Liu Y
    Mol Cell; 2022 Feb; 82(4):770-784.e9. PubMed ID: 35114100
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids.
    Frias MA; Mukhopadhyay S; Lehman E; Walasek A; Utter M; Menon D; Foster DA
    J Biol Chem; 2020 Jan; 295(1):263-274. PubMed ID: 31767684
    [TBL] [Abstract][Full Text] [Related]  

  • 31. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.
    Gan W; Dai X; Dai X; Xie J; Yin S; Zhu J; Wang C; Liu Y; Guo J; Wang M; Liu J; Hu J; Quinton RJ; Ganem NJ; Liu P; Asara JM; Pandolfi PP; Yang Y; He Z; Gao G; Wei W
    Nat Cell Biol; 2020 Feb; 22(2):246-256. PubMed ID: 32015438
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation.
    Yang W; Pang D; Chen M; Du C; Jia L; Wang L; He Y; Jiang W; Luo L; Yu Z; Mao M; Yuan Q; Tang P; Xia X; Cui Y; Jing B; Platero A; Liu Y; Wei Y; Worley PF; Xiao B
    Dev Cell; 2021 Mar; 56(6):811-825.e6. PubMed ID: 33725483
    [TBL] [Abstract][Full Text] [Related]  

  • 33. mTOR Senses Intracellular pH through Lysosome Dispersion from RHEB.
    Walton ZE; Brooks RC; Dang CV
    Bioessays; 2019 Jul; 41(7):e1800265. PubMed ID: 31157925
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1.
    Nada S; Okada M
    J Biochem; 2020 Dec; 168(6):621-632. PubMed ID: 32653916
    [TBL] [Abstract][Full Text] [Related]  

  • 35. CBAP modulates Akt-dependent TSC2 phosphorylation to promote Rheb-mTORC1 signaling and growth of T-cell acute lymphoblastic leukemia.
    Chiang YJ; Liao WT; Ho KC; Wang SH; Chen YG; Ho CL; Huang SF; Shih LY; Yang-Yen HF; Yen JJ
    Oncogene; 2019 Feb; 38(9):1432-1447. PubMed ID: 30266989
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of MAPK pathway is essential for suppressing Rheb-Y35N driven tumor growth.
    Wang Y; Hong X; Wang J; Yin Y; Zhang Y; Zhou Y; Piao HL; Liang Z; Zhang L; Li G; Xu G; Kwiatkowski DJ; Liu Y
    Oncogene; 2017 Feb; 36(6):756-765. PubMed ID: 27399332
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Phospholipase D-dependent mTOR complex 1 (mTORC1) activation by glutamine.
    Bernfeld E; Menon D; Vaghela V; Zerin I; Faruque P; Frias MA; Foster DA
    J Biol Chem; 2018 Oct; 293(42):16390-16401. PubMed ID: 30194281
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.
    Zhang C; Liu Y; Zhang Y; Wang X; Zhang T; Ding J
    J Mol Cell Biol; 2020 Sep; 12(9):741-744. PubMed ID: 32470140
    [No Abstract]   [Full Text] [Related]  

  • 39. Ubiquitously specific protease 4 inhibitor-Vialinin A attenuates inflammation and fibrosis in S100-induced hepatitis mice through Rheb/mTOR signalling.
    Xu J; Chen D; Jin L; Chen Z; Tu Y; Huang X; Xue F; Xu J; Chen M; Wang X; Chen Y
    J Cell Mol Med; 2021 Jan; 25(2):1140-1150. PubMed ID: 33295107
    [TBL] [Abstract][Full Text] [Related]  

  • 40. TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy.
    Nnah IC; Wang B; Saqcena C; Weber GF; Bonder EM; Bagley D; De Cegli R; Napolitano G; Medina DL; Ballabio A; Dobrowolski R
    Autophagy; 2019 Jan; 15(1):151-164. PubMed ID: 30145926
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.