269 related articles for article (PubMed ID: 30518210)
1. A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification.
Browne CM; Jiang B; Ficarro SB; Doctor ZM; Johnson JL; Card JD; Sivakumaren SC; Alexander WM; Yaron TM; Murphy CJ; Kwiatkowski NP; Zhang T; Cantley LC; Gray NS; Marto JA
J Am Chem Soc; 2019 Jan; 141(1):191-203. PubMed ID: 30518210
[TBL] [Abstract][Full Text] [Related]
2. Targeting protein kinases with selective and semipromiscuous covalent inhibitors.
Miller RM; Taunton J
Methods Enzymol; 2014; 548():93-116. PubMed ID: 25399643
[TBL] [Abstract][Full Text] [Related]
3. Label-Free Bottom-Up Proteomic Workflow for Simultaneously Assessing the Target Specificity of Covalent Drug Candidates and Their Off-Target Reactivity to Selected Proteins.
Yang Y; Shu YZ; Humphreys WG
Chem Res Toxicol; 2016 Jan; 29(1):109-16. PubMed ID: 26675335
[TBL] [Abstract][Full Text] [Related]
4. Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition.
Dalton SE; Dittus L; Thomas DA; Convery MA; Nunes J; Bush JT; Evans JP; Werner T; Bantscheff M; Murphy JA; Campos S
J Am Chem Soc; 2018 Jan; 140(3):932-939. PubMed ID: 29232121
[TBL] [Abstract][Full Text] [Related]
5. Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.
Rao S; Gurbani D; Du G; Everley RA; Browne CM; Chaikuad A; Tan L; Schröder M; Gondi S; Ficarro SB; Sim T; Kim ND; Berberich MJ; Knapp S; Marto JA; Westover KD; Sorger PK; Gray NS
Cell Chem Biol; 2019 Jun; 26(6):818-829.e9. PubMed ID: 30982749
[TBL] [Abstract][Full Text] [Related]
6. A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors.
Lanning BR; Whitby LR; Dix MM; Douhan J; Gilbert AM; Hett EC; Johnson TO; Joslyn C; Kath JC; Niessen S; Roberts LR; Schnute ME; Wang C; Hulce JJ; Wei B; Whiteley LO; Hayward MM; Cravatt BF
Nat Chem Biol; 2014 Sep; 10(9):760-767. PubMed ID: 25038787
[TBL] [Abstract][Full Text] [Related]
7. Cyclin-dependent kinase 7 inhibitors in cancer therapy.
Wang M; Wang T; Zhang X; Wu X; Jiang S
Future Med Chem; 2020 May; 12(9):813-833. PubMed ID: 32208930
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of cyclin-dependent kinase 7 suppresses human hepatocellular carcinoma by inducing apoptosis.
Zhong L; Yang S; Jia Y; Lei K
J Cell Biochem; 2018 Dec; 119(12):9742-9751. PubMed ID: 30145799
[TBL] [Abstract][Full Text] [Related]
9. Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity.
Ferguson FM; Doctor ZM; Ficarro SB; Browne CM; Marto JA; Johnson JL; Yaron TM; Cantley LC; Kim ND; Sim T; Berberich MJ; Kalocsay M; Sorger PK; Gray NS
Cell Chem Biol; 2019 Jun; 26(6):804-817.e12. PubMed ID: 30930164
[TBL] [Abstract][Full Text] [Related]
10. Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors.
Gao Y; Zhang T; Terai H; Ficarro SB; Kwiatkowski N; Hao MF; Sharma B; Christensen CL; Chipumuro E; Wong KK; Marto JA; Hammerman PS; Gray NS; George RE
Cell Chem Biol; 2018 Feb; 25(2):135-142.e5. PubMed ID: 29276047
[TBL] [Abstract][Full Text] [Related]
11. Discovery of MFH290: A Potent and Highly Selective Covalent Inhibitor for Cyclin-Dependent Kinase 12/13.
Liu Y; Hao M; Leggett AL; Gao Y; Ficarro SB; Che J; He Z; Olson CM; Marto JA; Kwiatkowski NP; Zhang T; Gray NS
J Med Chem; 2020 Jul; 63(13):6708-6726. PubMed ID: 32502343
[TBL] [Abstract][Full Text] [Related]
12. Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors.
Nandha Premnath P; Craig S; McInnes C
J Vis Exp; 2015 Oct; (105):e52441. PubMed ID: 26554946
[TBL] [Abstract][Full Text] [Related]
13. Direct Target Site Identification of a Sulfonyl-Triazole Covalent Kinase Probe by LC-MS Chemical Proteomics.
McCloud RL; Yuan K; Mahoney KE; Bai DL; Shabanowitz J; Ross MM; Hunt DF; Hsu KL
Anal Chem; 2021 Sep; 93(35):11946-11955. PubMed ID: 34431655
[TBL] [Abstract][Full Text] [Related]
14. Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype.
Olson CM; Liang Y; Leggett A; Park WD; Li L; Mills CE; Elsarrag SZ; Ficarro SB; Zhang T; Düster R; Geyer M; Sim T; Marto JA; Sorger PK; Westover KD; Lin CY; Kwiatkowski N; Gray NS
Cell Chem Biol; 2019 Jun; 26(6):792-803.e10. PubMed ID: 30905681
[TBL] [Abstract][Full Text] [Related]
15. Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors.
McAulay K; Hoyt EA; Thomas M; Schimpl M; Bodnarchuk MS; Lewis HJ; Barratt D; Bhavsar D; Robinson DM; Deery MJ; Ogg DJ; Bernardes GJL; Ward RA; Waring MJ; Kettle JG
J Am Chem Soc; 2020 Jun; 142(23):10358-10372. PubMed ID: 32412754
[TBL] [Abstract][Full Text] [Related]
16. Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors.
Brehmer D; Godl K; Zech B; Wissing J; Daub H
Mol Cell Proteomics; 2004 May; 3(5):490-500. PubMed ID: 14769951
[TBL] [Abstract][Full Text] [Related]
17. Chemoproteomic methods for covalent drug discovery.
Chan WC; Sharifzadeh S; Buhrlage SJ; Marto JA
Chem Soc Rev; 2021 Aug; 50(15):8361-8381. PubMed ID: 34143170
[TBL] [Abstract][Full Text] [Related]
18. Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway.
Abegg D; Tomanik M; Qiu N; Pechalrieu D; Shuster A; Commare B; Togni A; Herzon SB; Adibekian A
J Am Chem Soc; 2021 Dec; 143(48):20332-20342. PubMed ID: 34817176
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14.
Ferguson FM; Doctor ZM; Ficarro SB; Marto JA; Kim ND; Sim T; Gray NS
Bioorg Med Chem Lett; 2019 Aug; 29(15):1985-1993. PubMed ID: 31175010
[TBL] [Abstract][Full Text] [Related]
20. Electrophilic fragment-based design of reversible covalent kinase inhibitors.
Miller RM; Paavilainen VO; Krishnan S; Serafimova IM; Taunton J
J Am Chem Soc; 2013 Apr; 135(14):5298-301. PubMed ID: 23540679
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]