BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 30521586)

  • 1. Interleukin-6 inhibition of hERG underlies risk for acquired long QT in cardiac and systemic inflammation.
    Aromolaran AS; Srivastava U; Alí A; Chahine M; Lazaro D; El-Sherif N; Capecchi PL; Laghi-Pasini F; Lazzerini PE; Boutjdir M
    PLoS One; 2018; 13(12):e0208321. PubMed ID: 30521586
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Familial and acquired long qt syndrome and the cardiac rapid delayed rectifier potassium current.
    Witchel HJ; Hancox JC
    Clin Exp Pharmacol Physiol; 2000 Oct; 27(10):753-66. PubMed ID: 11022966
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanisms of gefitinib-induced QT prolongation.
    Jie LJ; Li YD; Zhang HQ; Mao L; Xie HB; Zhou FG; Zhou TL; Xie D; Lin JL; Li GY; Cai BN; Zhang YH; Wang Y
    Eur J Pharmacol; 2021 Nov; 910():174441. PubMed ID: 34474028
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.
    Thomas D; Karle CA; Kiehn J
    Curr Pharm Des; 2006; 12(18):2271-83. PubMed ID: 16787254
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of rapid delayed rectifier potassium current (I
    Chen Y; Yin C; Yang Y; Fan Z; Shang J; Tan W
    J Electrocardiol; 2017; 50(4):437-443. PubMed ID: 28646979
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pathogenesis of the Novel Autoimmune-Associated Long-QT Syndrome.
    Yue Y; Castrichini M; Srivastava U; Fabris F; Shah K; Li Z; Qu Y; El-Sherif N; Zhou Z; January C; Hussain MM; Jiang XC; Sobie EA; Wahren-Herlenius M; Chahine M; Capecchi PL; Laghi-Pasini F; Lazzerini PE; Boutjdir M
    Circulation; 2015 Jul; 132(4):230-40. PubMed ID: 25995318
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT.
    Mechakra A; Vincent Y; Chevalier P; Millat G; Ficker E; Jastrzebski M; Poulin H; Pouliot V; Chahine M; Christé G
    Gene; 2014 Feb; 536(2):348-56. PubMed ID: 24334129
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Macrophage-Dependent Interleukin-6-Production and Inhibition of
    Chowdhury MKH; Martinez-Mateu L; Do J; Aromolaran KA; Saiz J; Aromolaran AS
    Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681909
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti-Ro52 antibody acts on the S5-pore linker of hERG to chronically reduce channel expression.
    Szendrey J; Lamothe SM; Vanner S; Guo J; Yang T; Li W; Davis J; Joneja M; Baranchuk A; Zhang S
    Cardiovasc Res; 2019 Aug; 115(10):1500-1511. PubMed ID: 30544220
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cardiac hERG K
    Su S; Sun J; Wang Y; Xu Y
    Handb Exp Pharmacol; 2021; 267():139-166. PubMed ID: 33829343
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The long QT syndrome: new diagnostic and therapeutic approach in the era of molecular biology.
    Priori SG; Cantù F; Schwartz PJ
    Schweiz Med Wochenschr; 1996 Oct; 126(41):1727-31. PubMed ID: 8893413
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The hERG channel activator, RPR260243, enhances protective
    Shi YP; Pang Z; Venkateshappa R; Gunawan M; Kemp J; Truong E; Chang C; Lin E; Shafaattalab S; Faizi S; Rayani K; Tibbits GF; Claydon VE; Claydon TW
    Am J Physiol Heart Circ Physiol; 2020 Aug; 319(2):H251-H261. PubMed ID: 32559136
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [HERG K+ channel, the target of anti-arrhythmias drugs].
    Guan FY; Yang SJ
    Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue as a Sensitive Test System for QT Prolongation and Arrhythmic Triggers.
    Lemoine MD; Krause T; Koivumäki JT; Prondzynski M; Schulze ML; Girdauskas E; Willems S; Hansen A; Eschenhagen T; Christ T
    Circ Arrhythm Electrophysiol; 2018 Jul; 11(7):e006035. PubMed ID: 29925535
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization.
    Perry MD; Ng CA; Mangala MM; Ng TYM; Hines AD; Liang W; Xu MJO; Hill AP; Vandenberg JI
    Cardiovasc Res; 2020 Jul; 116(8):1434-1445. PubMed ID: 31628797
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells.
    De Waard S; Montnach J; Ribeiro B; Nicolas S; Forest V; Charpentier F; Mangoni ME; Gaborit N; Ronjat M; Loussouarn G; Lemarchand P; De Waard M
    Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 32998413
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Balance Between Rapid Delayed Rectifier K
    Hegyi B; Chen-Izu Y; Izu LT; Rajamani S; Belardinelli L; Bers DM; Bányász T
    Circ Arrhythm Electrophysiol; 2020 Apr; 13(4):e008130. PubMed ID: 32202931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia.
    Zhan G; Wang F; Ding YQ; Li XH; Li YX; Zhao ZR; Li JX; Liu Y; Zhao X; Yan CC; Li BX
    J Cell Mol Med; 2021 Jun; 25(11):4938-4949. PubMed ID: 33939251
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intracellular uptake of agents that block the hERG channel can confound the assessment of QT interval prolongation and arrhythmic risk.
    Burashnikov A; Barajas-Martinez H; Cox R; Demitrack MA; Fossler MJ; Kramer M; Kleiman RB; Kowey P; Antzelevitch C
    Heart Rhythm; 2021 Dec; 18(12):2177-2186. PubMed ID: 34481984
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Contribution of cytokine-mediated prolongation of QTc interval to the multi-hit theory of Torsade de Pointes.
    Cupelli M; Ginjupalli VKM; Chen L; Capecchi PL; Lazzerini PE; Boutjdir M; El-Sherif N
    Biochem Biophys Res Commun; 2023 May; 655():82-89. PubMed ID: 36933311
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.