BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 30523156)

  • 1. Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1-induced steatosis.
    Tillander V; Miniami A; Alves-Bezerra M; Coleman RA; Cohen DE
    J Biol Chem; 2019 Feb; 294(6):2009-2020. PubMed ID: 30523156
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis.
    Alves-Bezerra M; Li Y; Acuña M; Ivanova AA; Corey KE; Ortlund EA; Cohen DE
    Hepatology; 2019 Aug; 70(2):496-510. PubMed ID: 30516845
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glycerol-3-phosphate acyltransferase 1 deficiency in ob/ob mice diminishes hepatic steatosis but does not protect against insulin resistance or obesity.
    Wendel AA; Li LO; Li Y; Cline GW; Shulman GI; Coleman RA
    Diabetes; 2010 Jun; 59(6):1321-9. PubMed ID: 20200319
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization.
    Kawano Y; Ersoy BA; Li Y; Nishiumi S; Yoshida M; Cohen DE
    Mol Cell Biol; 2014 Jul; 34(13):2396-408. PubMed ID: 24732803
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance.
    Nagle CA; An J; Shiota M; Torres TP; Cline GW; Liu ZX; Wang S; Catlin RL; Shulman GI; Newgard CB; Coleman RA
    J Biol Chem; 2007 May; 282(20):14807-15. PubMed ID: 17389595
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Up-regulation of thioesterase superfamily member 2 in skeletal muscle promotes hepatic steatosis and insulin resistance in mice.
    Imai N; Nicholls HT; Alves-Bezerra M; Li Y; Ivanova AA; Ortlund EA; Cohen DE
    Hepatology; 2022 Jan; 75(1):154-169. PubMed ID: 34433228
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism.
    Kang HW; Niepel MW; Han S; Kawano Y; Cohen DE
    FASEB J; 2012 May; 26(5):2209-21. PubMed ID: 22345407
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress.
    Ersoy BA; Maner-Smith KM; Li Y; Alpertunga I; Cohen DE
    J Clin Invest; 2018 Jan; 128(1):141-156. PubMed ID: 29202465
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thioesterase superfamily member 2/Acyl-CoA thioesterase 13 (Them2/Acot13) regulates adaptive thermogenesis in mice.
    Kang HW; Ozdemir C; Kawano Y; LeClair KB; Vernochet C; Kahn CR; Hagen SJ; Cohen DE
    J Biol Chem; 2013 Nov; 288(46):33376-86. PubMed ID: 24072708
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.
    Hammond LE; Neschen S; Romanelli AJ; Cline GW; Ilkayeva OR; Shulman GI; Muoio DM; Coleman RA
    J Biol Chem; 2005 Jul; 280(27):25629-36. PubMed ID: 15878874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation.
    Wendel AA; Cooper DE; Ilkayeva OR; Muoio DM; Coleman RA
    J Biol Chem; 2013 Sep; 288(38):27299-27306. PubMed ID: 23908354
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of Triglyceride Metabolism. II. Function of mitochondrial GPAT1 in the regulation of triacylglycerol biosynthesis and insulin action.
    Gonzalez-Baró MR; Lewin TM; Coleman RA
    Am J Physiol Gastrointest Liver Physiol; 2007 May; 292(5):G1195-9. PubMed ID: 17158253
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice.
    Neschen S; Morino K; Hammond LE; Zhang D; Liu ZX; Romanelli AJ; Cline GW; Pongratz RL; Zhang XM; Choi CS; Coleman RA; Shulman GI
    Cell Metab; 2005 Jul; 2(1):55-65. PubMed ID: 16054099
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation.
    Lindén D; William-Olsson L; Ahnmark A; Ekroos K; Hallberg C; Sjögren HP; Becker B; Svensson L; Clapham JC; Oscarsson J; Schreyer S
    FASEB J; 2006 Mar; 20(3):434-43. PubMed ID: 16507761
    [TBL] [Abstract][Full Text] [Related]  

  • 15. GPAT1 Activity and Abundant Palmitic Acid Impair Insulin Suppression of Hepatic Glucose Production in Primary Mouse Hepatocytes.
    Zhang C; Steadman M; Santos HP; Shaikh SR; Xavier RM
    J Nutr; 2024 Apr; 154(4):1109-1118. PubMed ID: 38354952
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.
    Zhang C; Wendel AA; Keogh MR; Harris TE; Chen J; Coleman RA
    Proc Natl Acad Sci U S A; 2012 Jan; 109(5):1667-72. PubMed ID: 22307628
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice.
    Yazdi M; Ahnmark A; William-Olsson L; Snaith M; Turner N; Osla F; Wedin M; Asztély AK; Elmgren A; Bohlooly-Y M; Schreyer S; Lindén D
    Biochem Biophys Res Commun; 2008 May; 369(4):1065-70. PubMed ID: 18339309
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition.
    Lewin TM; de Jong H; Schwerbrock NJ; Hammond LE; Watkins SM; Combs TP; Coleman RA
    Biochim Biophys Acta; 2008; 1781(6-7):352-8. PubMed ID: 18522808
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis.
    Lindén D; William-Olsson L; Rhedin M; Asztély AK; Clapham JC; Schreyer S
    J Lipid Res; 2004 Jul; 45(7):1279-88. PubMed ID: 15102885
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor.
    Zhang C; Cooper DE; Grevengoed TJ; Li LO; Klett EL; Eaton JM; Harris TE; Coleman RA
    Am J Physiol Endocrinol Metab; 2014 Aug; 307(3):E305-15. PubMed ID: 24939733
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.