BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 30524887)

  • 1. Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation.
    Adam I; Dewi DL; Mooiweer J; Sadik A; Mohapatra SR; Berdel B; Keil M; Sonner JK; Thedieck K; Rose AJ; Platten M; Heiland I; Trump S; Opitz CA
    Oncoimmunology; 2018; 7(12):e1486353. PubMed ID: 30524887
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tryptophan Depletion Modulates Tryptophanyl-tRNA Synthetase-Mediated High-Affinity Tryptophan Uptake into Human Cells.
    Yokosawa T; Sato A; Wakasugi K
    Genes (Basel); 2020 Nov; 11(12):. PubMed ID: 33261077
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The high-affinity tryptophan uptake transport system in human cells.
    Wakasugi K; Yokosawa T
    Biochem Soc Trans; 2024 May; ():. PubMed ID: 38813870
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of Indoleamine 2, 3-dioxygenase 1 (IDO1) and Tryptophanyl-tRNA Synthetase (WARS) in Gastric Cancer Molecular Subtypes.
    Lu S; Wang LJ; Lombardo K; Kwak Y; Kim WH; Resnick MB
    Appl Immunohistochem Mol Morphol; 2020; 28(5):360-368. PubMed ID: 31033497
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tryptophanyl-tRNA synthetase mediates high-affinity tryptophan uptake into human cells.
    Miyanokoshi M; Yokosawa T; Wakasugi K
    J Biol Chem; 2018 Jun; 293(22):8428-8438. PubMed ID: 29666190
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modulation of cellular tryptophan metabolism in human fibroblasts by transforming growth factor-beta: selective inhibition of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA synthetase gene expression.
    Yuan W; Collado-Hidalgo A; Yufit T; Taylor M; Varga J
    J Cell Physiol; 1998 Oct; 177(1):174-86. PubMed ID: 9731757
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Indoleamine 2,3-dioxygenase depletes tryptophan, activates general control non-derepressible 2 kinase and down-regulates key enzymes involved in fatty acid synthesis in primary human CD4+ T cells.
    Eleftheriadis T; Pissas G; Antoniadi G; Liakopoulos V; Stefanidis I
    Immunology; 2015 Oct; 146(2):292-300. PubMed ID: 26147366
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Depletion of tryptophan is not involved in expression of tryptophanyl-tRNA synthetase mediated by interferon.
    Flohr T; Bange FC; von Euch A; Kiekenbeck M; Böttger EC
    Infect Immun; 1992 Oct; 60(10):4418-21. PubMed ID: 1398953
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice.
    Aslamkhan AG; Xu Q; Loughlin A; Vu H; Pacchione S; Bhatt B; Garfinkel I; Styring TG; LaFranco-Scheuch L; Pearson K; Reynolds S; Li N; Zhou H; Miller JR; Solban N; Bass A; Glaab WE
    Toxicol Appl Pharmacol; 2020 Nov; 406():115216. PubMed ID: 32871117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amino acid deprivation links BLIMP-1 to the immunomodulatory enzyme indoleamine 2,3-dioxygenase.
    Barnes NA; Stephenson SJ; Tooze RM; Doody GM
    J Immunol; 2009 Nov; 183(9):5768-77. PubMed ID: 19828629
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production.
    Mohapatra SR; Sadik A; Sharma S; Poschet G; Gegner HM; Lanz TV; Lucarelli P; Klingmüller U; Platten M; Heiland I; Opitz CA
    Front Immunol; 2021; 12():590532. PubMed ID: 33679737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting tryptophan availability to tumors: the answer to immune escape?
    Badawy AA
    Immunol Cell Biol; 2018 Nov; 96(10):1026-1034. PubMed ID: 29888434
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.
    Sonner JK; Deumelandt K; Ott M; Thomé CM; Rauschenbach KJ; Schulz S; Munteanu B; Mohapatra S; Adam I; Hofer AC; Feuerer M; Opitz CA; Hopf C; Wick W; Platten M
    Oncoimmunology; 2016; 5(12):e1240858. PubMed ID: 28123877
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preparation and evaluation of L- and D-5-[
    Tang T; Gill HS; Ogasawara A; Tinianow JN; Vanderbilt AN; Williams SP; Hatzivassiliou G; White S; Sandoval W; DeMent K; Wong M; Marik J
    Nucl Med Biol; 2017 Aug; 51():10-17. PubMed ID: 28511073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting the IDO1/TDO2-KYN-AhR Pathway for Cancer Immunotherapy - Challenges and Opportunities.
    Cheong JE; Sun L
    Trends Pharmacol Sci; 2018 Mar; 39(3):307-325. PubMed ID: 29254698
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The end of the road for the tryptophan depletion concept in pregnancy and infection.
    Badawy AA; Namboodiri AM; Moffett JR
    Clin Sci (Lond); 2016 Aug; 130(15):1327-33. PubMed ID: 27358028
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GCN2- and eIF2α-phosphorylation-independent, but ATF4-dependent, induction of CARE-containing genes in methionine-deficient cells.
    Mazor KM; Stipanuk MH
    Amino Acids; 2016 Dec; 48(12):2831-2842. PubMed ID: 27613409
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses.
    Nguyen TTT; Choi YH; Lee WK; Ji Y; Chun E; Kim YH; Lee JE; Jung HS; Suh JH; Kim S; Jin M
    Cell Rep; 2023 Jan; 42(1):111905. PubMed ID: 36640342
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assignment of the human tryptophanyl-tRNA synthetase gene (WARS) to chromosome 14q32.2 --> q32.32.
    Børglum AD; Flint T; Tommerup N; Fleckner J; Justesen J; Kruse TA
    Cytogenet Cell Genet; 1996; 73(1-2):99-103. PubMed ID: 8646895
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma.
    Mohapatra SR; Sadik A; Tykocinski LO; Dietze J; Poschet G; Heiland I; Opitz CA
    Front Immunol; 2019; 10():2762. PubMed ID: 31866995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.