BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 30530493)

  • 21. Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP.
    Birukova AA; Burdette D; Moldobaeva N; Xing J; Fu P; Birukov KG
    Microvasc Res; 2010 Mar; 79(2):128-38. PubMed ID: 19962392
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Impaired cAMP processivity by phosphodiesterase-protein kinase A complexes in acrodysostosis.
    Venkatakrishnan V; Ghode A; Tulsian NK; Anand GS
    Front Mol Biosci; 2023; 10():1202268. PubMed ID: 37808519
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability.
    Naikawadi RP; Cheng N; Vogel SM; Qian F; Wu D; Malik AB; Ye RD
    Circ Res; 2012 Dec; 111(12):1517-27. PubMed ID: 22965143
    [TBL] [Abstract][Full Text] [Related]  

  • 24. P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells.
    Hampson E; Tsonou E; Baker MJ; Hornigold DC; Hubbard RE; Massey A; Welch HCE
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572121
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.
    Montero JC; Seoane S; Pandiella A
    Cell Signal; 2013 Nov; 25(11):2281-9. PubMed ID: 23899556
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP.
    Li Y; Dillon TJ; Takahashi M; Earley KT; Stork PJ
    J Biol Chem; 2016 Oct; 291(41):21584-21595. PubMed ID: 27531745
    [TBL] [Abstract][Full Text] [Related]  

  • 27. P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.
    Hernández-Negrete I; Carretero-Ortega J; Rosenfeldt H; Hernández-García R; Calderón-Salinas JV; Reyes-Cruz G; Gutkind JS; Vázquez-Prado J
    J Biol Chem; 2007 Aug; 282(32):23708-15. PubMed ID: 17565979
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Adenylate control in cAMP signaling: implications for adaptation in signalosomes.
    Tulsian NK; Ghode A; Anand GS
    Biochem J; 2020 Aug; 477(16):2981-2998. PubMed ID: 32722762
    [TBL] [Abstract][Full Text] [Related]  

  • 29. PREX1 Protein Function Is Negatively Regulated Downstream of Receptor Tyrosine Kinase Activation by p21-activated Kinases (PAKs).
    Barrows D; He JZ; Parsons R
    J Biol Chem; 2016 Sep; 291(38):20042-54. PubMed ID: 27481946
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Protein kinase-A activity in PRKAR1A-mutant cells, and regulation of mitogen-activated protein kinases ERK1/2.
    Robinson-White A; Hundley TR; Shiferaw M; Bertherat J; Sandrini F; Stratakis CA
    Hum Mol Genet; 2003 Jul; 12(13):1475-84. PubMed ID: 12812976
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cooperation of Epac1/Rap1/Akt and PKA in prostaglandin E(2) -induced proliferation of human umbilical cord blood derived mesenchymal stem cells: involvement of c-Myc and VEGF expression.
    Jang MW; Yun SP; Park JH; Ryu JM; Lee JH; Han HJ
    J Cell Physiol; 2012 Dec; 227(12):3756-67. PubMed ID: 22378492
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α.
    Barber MA; Hendrickx A; Beullens M; Ceulemans H; Oxley D; Thelen S; Thelen M; Bollen M; Welch HC
    Biochem J; 2012 Apr; 443(1):173-83. PubMed ID: 22242915
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation.
    Bruystens JG; Wu J; Fortezzo A; Del Rio J; Nielsen C; Blumenthal DK; Rock R; Stefan E; Taylor SS
    J Mol Biol; 2016 Dec; 428(24 Pt B):4890-4904. PubMed ID: 27825928
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation.
    Birukova AA; Zagranichnaya T; Fu P; Alekseeva E; Chen W; Jacobson JR; Birukov KG
    Exp Cell Res; 2007 Jul; 313(11):2504-20. PubMed ID: 17493609
    [TBL] [Abstract][Full Text] [Related]  

  • 35. PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.
    Liu HJ; Ooms LM; Srijakotre N; Man J; Vieusseux J; Waters JE; Feng Y; Bailey CG; Rasko JE; Price JT; Mitchell CA
    J Biol Chem; 2016 Aug; 291(33):17258-70. PubMed ID: 27358402
    [TBL] [Abstract][Full Text] [Related]  

  • 36. P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer.
    Dillon LM; Bean JR; Yang W; Shee K; Symonds LK; Balko JM; McDonald WH; Liu S; Gonzalez-Angulo AM; Mills GB; Arteaga CL; Miller TW
    Oncogene; 2015 Jul; 34(30):3968-76. PubMed ID: 25284585
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation.
    Mei FC; Qiao J; Tsygankova OM; Meinkoth JL; Quilliam LA; Cheng X
    J Biol Chem; 2002 Mar; 277(13):11497-504. PubMed ID: 11801596
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Active site coupling in PDE:PKA complexes promotes resetting of mammalian cAMP signaling.
    Krishnamurthy S; Moorthy BS; Xin Xiang L; Xin Shan L; Bharatham K; Tulsian NK; Mihalek I; Anand GS
    Biophys J; 2014 Sep; 107(6):1426-40. PubMed ID: 25229150
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mechanisms of cyclic AMP/protein kinase A- and glucocorticoid-mediated apoptosis using S49 lymphoma cells as a model system.
    Keshwani MM; Kanter JR; Ma Y; Wilderman A; Darshi M; Insel PA; Taylor SS
    Proc Natl Acad Sci U S A; 2015 Oct; 112(41):12681-6. PubMed ID: 26417071
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Phosphodiesterases catalyze hydrolysis of cAMP-bound to regulatory subunit of protein kinase A and mediate signal termination.
    Moorthy BS; Gao Y; Anand GS
    Mol Cell Proteomics; 2011 Feb; 10(2):M110.002295. PubMed ID: 20923972
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.