205 related articles for article (PubMed ID: 30530624)
1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[
Nicholson HE; Alsharif WF; Comeau AB; Mesangeau C; Intagliata S; Mottinelli M; McCurdy CR; Bowen WD
J Pharmacol Exp Ther; 2019 Feb; 368(2):272-281. PubMed ID: 30530624
[TBL] [Abstract][Full Text] [Related]
2. Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity.
Liu CZ; Mottinelli M; Nicholson HE; McVeigh BM; Wong NK; McCurdy CR; Bowen WD
Eur J Pharmacol; 2021 Sep; 906():174263. PubMed ID: 34144027
[TBL] [Abstract][Full Text] [Related]
3. Sigma-2 Receptors Play a Role in Cellular Metabolism: Stimulation of Glycolytic Hallmarks by CM764 in Human SK-N-SH Neuroblastoma.
Nicholson H; Mesangeau C; McCurdy CR; Bowen WD
J Pharmacol Exp Ther; 2016 Feb; 356(2):232-43. PubMed ID: 26574517
[TBL] [Abstract][Full Text] [Related]
4. Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity.
Nicholson H; Comeau A; Mesangeau C; McCurdy CR; Bowen WD
J Pharmacol Exp Ther; 2015 Aug; 354(2):203-12. PubMed ID: 26034081
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist, in rodents.
Kaushal N; Robson MJ; Vinnakota H; Narayanan S; Avery BA; McCurdy CR; Matsumoto RR
AAPS J; 2011 Sep; 13(3):336-46. PubMed ID: 21494909
[TBL] [Abstract][Full Text] [Related]
6. Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro.
Kaushal N; Robson MJ; Rosen A; McCurdy CR; Matsumoto RR
Eur J Pharmacol; 2014 Feb; 724():193-203. PubMed ID: 24380829
[TBL] [Abstract][Full Text] [Related]
7. Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the sigma1 binding site.
Zampieri D; Grazia Mamolo M; Laurini E; Zanette C; Florio C; Collina S; Rossi D; Azzolina O; Vio L
Eur J Med Chem; 2009 Jan; 44(1):124-30. PubMed ID: 18440098
[TBL] [Abstract][Full Text] [Related]
8. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
Berardi F; Abate C; Ferorelli S; Uricchio V; Colabufo NA; Niso M; Perrone R
J Med Chem; 2009 Dec; 52(23):7817-28. PubMed ID: 19842660
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo.
Kaushal N; Seminerio MJ; Robson MJ; McCurdy CR; Matsumoto RR
Eur Neuropsychopharmacol; 2013 Aug; 23(8):960-71. PubMed ID: 22921523
[TBL] [Abstract][Full Text] [Related]
10. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
[TBL] [Abstract][Full Text] [Related]
11. 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives: novel, potent and selective sigma1 receptor ligands.
Ucar H; Cacciaguerra S; Spampinato S; Van derpoorten K; Isa M; Kanyonyo M; Poupaert JH
Eur J Pharmacol; 1997 Sep; 335(2-3):267-73. PubMed ID: 9369382
[TBL] [Abstract][Full Text] [Related]
12. Structure-activity comparison of YZ-069, a novel sigma ligand, and four analogs in receptor binding and behavioral studies.
Matsumoto RR; Potelleret FH; Mack A; Pouw B; Zhang Y; Bowen WD
Pharmacol Biochem Behav; 2004 Apr; 77(4):775-81. PubMed ID: 15099923
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and in vitro Evaluation of Novel Indole-Based Sigma Receptors Ligands.
Yarim M; Koksal M; Schepmann D; Wünsch B
Chem Biol Drug Des; 2011 Nov; 78(5):869-75. PubMed ID: 21848665
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands.
Donnier-Maréchal M; Carato P; Le Broc D; Furman C; Melnyk P
Eur J Med Chem; 2015 Mar; 92():575-82. PubMed ID: 25602932
[TBL] [Abstract][Full Text] [Related]
15. Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 2. Spiro-joined benzofuran, isobenzofuran, and benzopyran piperidines.
Moltzen EK; Perregaard J; Meier E
J Med Chem; 1995 May; 38(11):2009-17. PubMed ID: 7783132
[TBL] [Abstract][Full Text] [Related]
16. Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine σ₁ receptor ligands.
Moussa IA; Banister SD; Akladios FN; Chua SW; Kassiou M
Bioorg Med Chem Lett; 2011 Oct; 21(19):5707-10. PubMed ID: 21871797
[TBL] [Abstract][Full Text] [Related]
17. Structure activity relationship study of benzo[d]thiazol-2(3H)one based σ receptor ligands.
Bhat R; Fishback JA; Matsumoto RR; Poupaert JH; McCurdy CR
Bioorg Med Chem Lett; 2013 Sep; 23(17):5011-3. PubMed ID: 23867168
[TBL] [Abstract][Full Text] [Related]
18. The sigma-1 receptor antagonist PB212 reduces the Ca²⁺-release through the inositol (1, 4, 5)-trisphosphate receptor in SK-N-SH cells.
Gasparre G; Abate C; Berardi F; Cassano G
Eur J Pharmacol; 2012 Jun; 684(1-3):59-63. PubMed ID: 22465185
[TBL] [Abstract][Full Text] [Related]
19. Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles.
Perregaard J; Moltzen EK; Meier E; Sánchez C
J Med Chem; 1995 May; 38(11):1998-2008. PubMed ID: 7783131
[TBL] [Abstract][Full Text] [Related]
20. 1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 (sigma1) and sigma-2 (sigma2) receptor ligands: a review.
Berardi F; Abate C; Ferorelli S; Colabufo NA; Perrone R
Cent Nerv Syst Agents Med Chem; 2009 Sep; 9(3):205-19. PubMed ID: 20021355
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
