236 related articles for article (PubMed ID: 30535757)
1. Advanced In Vitro HepaRG Culture Systems for Xenobiotic Metabolism and Toxicity Characterization.
Ashraf MN; Asghar MW; Rong Y; Doschak MR; Kiang TKL
Eur J Drug Metab Pharmacokinet; 2019 Aug; 44(4):437-458. PubMed ID: 30535757
[TBL] [Abstract][Full Text] [Related]
2. HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism.
Rebelo SP; Costa R; Estrada M; Shevchenko V; Brito C; Alves PM
Arch Toxicol; 2015 Aug; 89(8):1347-58. PubMed ID: 25107451
[TBL] [Abstract][Full Text] [Related]
3. Overexpression of the constitutive androstane receptor and shaken 3D-culturing increase biotransformation and oxidative phosphorylation and sensitivity to mitochondrial amiodarone toxicity of HepaRG cells.
van der Mark VA; Adam AAA; Chang JC; Oude Elferink RP; Chamuleau RAFM; Hoekstra R
Toxicol Appl Pharmacol; 2020 Jul; 399():115055. PubMed ID: 32428594
[TBL] [Abstract][Full Text] [Related]
4. 3D organotypic HepaRG cultures as in vitro model for acute and repeated dose toxicity studies.
Mueller D; Krämer L; Hoffmann E; Klein S; Noor F
Toxicol In Vitro; 2014 Feb; 28(1):104-12. PubMed ID: 23850736
[TBL] [Abstract][Full Text] [Related]
5. An Automated Multiplexed Hepatotoxicity and CYP Induction Assay Using HepaRG Cells in 2D and 3D.
Ott LM; Ramachandran K; Stehno-Bittel L
SLAS Discov; 2017 Jun; 22(5):614-625. PubMed ID: 28346810
[TBL] [Abstract][Full Text] [Related]
6. From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.
Ramaiahgari SC; Waidyanatha S; Dixon D; DeVito MJ; Paules RS; Ferguson SS
Toxicol Sci; 2017 Sep; 159(1):124-136. PubMed ID: 28633424
[TBL] [Abstract][Full Text] [Related]
7. Phase 1 and phase 2 drug metabolism and bile acid production of HepaRG cells in a bioartificial liver in absence of dimethyl sulfoxide.
Hoekstra R; Nibourg GA; van der Hoeven TV; Plomer G; Seppen J; Ackermans MT; Camus S; Kulik W; van Gulik TM; Elferink RP; Chamuleau RA
Drug Metab Dispos; 2013 Mar; 41(3):562-7. PubMed ID: 23238784
[TBL] [Abstract][Full Text] [Related]
8. HepaRG-Progenitor Cell Derived Hepatocytes Cultured in Bioartificial Livers Are Protected from Healthy- and Acute Liver Failure-Plasma Induced Toxicity.
van Wenum M; Treskes P; Adam AAA; van der Mark VA; Jongejan A; Moerland PD; van Gulik TM; Oude Elferink RPJ; Chamuleau RAFM; Hoekstra R
Cell Physiol Biochem; 2018; 48(5):2189-2204. PubMed ID: 30110678
[TBL] [Abstract][Full Text] [Related]
9. HepaRG culture in tethered spheroids as an in vitro three-dimensional model for drug safety screening.
Wang Z; Luo X; Anene-Nzelu C; Yu Y; Hong X; Singh NH; Xia L; Liu S; Yu H
J Appl Toxicol; 2015 Aug; 35(8):909-17. PubMed ID: 25512232
[TBL] [Abstract][Full Text] [Related]
10. 3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies.
Gunness P; Mueller D; Shevchenko V; Heinzle E; Ingelman-Sundberg M; Noor F
Toxicol Sci; 2013 May; 133(1):67-78. PubMed ID: 23377618
[TBL] [Abstract][Full Text] [Related]
11. Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.
Bell CC; Lauschke VM; Vorrink SU; Palmgren H; Duffin R; Andersson TB; Ingelman-Sundberg M
Drug Metab Dispos; 2017 Apr; 45(4):419-429. PubMed ID: 28137721
[TBL] [Abstract][Full Text] [Related]
12. Towards better prediction of xenobiotic genotoxicity: CometChip technology coupled with a 3D model of HepaRG human liver cells.
Barranger A; Le Hégarat L
Arch Toxicol; 2022 Jul; 96(7):2087-2095. PubMed ID: 35419617
[TBL] [Abstract][Full Text] [Related]
13. Comparative analysis of 3D culture methods on human HepG2 cells.
Luckert C; Schulz C; Lehmann N; Thomas M; Hofmann U; Hammad S; Hengstler JG; Braeuning A; Lampen A; Hessel S
Arch Toxicol; 2017 Jan; 91(1):393-406. PubMed ID: 26872951
[TBL] [Abstract][Full Text] [Related]
14. Engineering EMT using 3D micro-scaffold to promote hepatic functions for drug hepatotoxicity evaluation.
Wang J; Chen F; Liu L; Qi C; Wang B; Yan X; Huang C; Hou W; Zhang MQ; Chen Y; Du Y
Biomaterials; 2016 Jun; 91():11-22. PubMed ID: 26994875
[TBL] [Abstract][Full Text] [Related]
15. Selecting Cells for Bioartificial Liver Devices and the Importance of a 3D Culture Environment: A Functional Comparison between the HepaRG and C3A Cell Lines.
van Wenum M; Adam AA; Hakvoort TB; Hendriks EJ; Shevchenko V; van Gulik TM; Chamuleau RA; Hoekstra R
Int J Biol Sci; 2016; 12(8):964-78. PubMed ID: 27489500
[TBL] [Abstract][Full Text] [Related]
16. Rat primary hepatocytes show enhanced performance and sensitivity to acetaminophen during three-dimensional culture on a polystyrene scaffold designed for routine use.
Schutte M; Fox B; Baradez MO; Devonshire A; Minguez J; Bokhari M; Przyborski S; Marshall D
Assay Drug Dev Technol; 2011 Oct; 9(5):475-86. PubMed ID: 21675871
[TBL] [Abstract][Full Text] [Related]
17. AMC-Bio-Artificial Liver culturing enhances mitochondrial biogenesis in human liver cell lines: The role of oxygen, medium perfusion and 3D configuration.
Adam AAA; van Wenum M; van der Mark VA; Jongejan A; Moerland PD; Houtkooper RH; Wanders RJA; Oude Elferink RP; Chamuleau RAFM; Hoekstra R
Mitochondrion; 2018 Mar; 39():30-42. PubMed ID: 28844938
[TBL] [Abstract][Full Text] [Related]
18. Increased hepatic functionality of the human hepatoma cell line HepaRG cultured in the AMC bioreactor.
Nibourg GA; Hoekstra R; van der Hoeven TV; Ackermans MT; Hakvoort TB; van Gulik TM; Chamuleau RA
Int J Biochem Cell Biol; 2013 Aug; 45(8):1860-8. PubMed ID: 23770120
[TBL] [Abstract][Full Text] [Related]
19. Fish hepatocyte spheroids - A powerful (though underexplored) alternative in vitro model to study hepatotoxicity.
Alves RF; Rocha E; Madureira TV
Comp Biochem Physiol C Toxicol Pharmacol; 2022 Dec; 262():109470. PubMed ID: 36122680
[TBL] [Abstract][Full Text] [Related]
20. Technological advancements for the development of stem cell-based models for hepatotoxicity testing.
Natale A; Vanmol K; Arslan A; Van Vlierberghe S; Dubruel P; Van Erps J; Thienpont H; Buzgo M; Boeckmans J; De Kock J; Vanhaecke T; Rogiers V; Rodrigues RM
Arch Toxicol; 2019 Jul; 93(7):1789-1805. PubMed ID: 31037322
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
