169 related articles for article (PubMed ID: 30536855)
1. Engineering an EGFR-binding Gp2 domain for increased hydrophilicity.
Du F; Kruziki MA; Zudock EJ; Zhang Y; Lown PS; Hackel BJ
Biotechnol Bioeng; 2019 Mar; 116(3):526-535. PubMed ID: 30536855
[TBL] [Abstract][Full Text] [Related]
2. Engineered Charge Redistribution of Gp2 Proteins through Guided Diversity for Improved PET Imaging of Epidermal Growth Factor Receptor.
Case BA; Kruziki MA; Johnson SM; Hackel BJ
Bioconjug Chem; 2018 May; 29(5):1646-1658. PubMed ID: 29579383
[TBL] [Abstract][Full Text] [Related]
3. Designed hydrophilic and charge mutations of the fibronectin domain: towards tailored protein biodistribution.
Hackel BJ; Sathirachinda A; Gambhir SS
Protein Eng Des Sel; 2012 Oct; 25(10):639-47. PubMed ID: 22691700
[TBL] [Abstract][Full Text] [Related]
4. A 45-Amino-Acid Scaffold Mined from the PDB for High-Affinity Ligand Engineering.
Kruziki MA; Bhatnagar S; Woldring DR; Duong VT; Hackel BJ
Chem Biol; 2015 Jul; 22(7):946-56. PubMed ID: 26165154
[TBL] [Abstract][Full Text] [Related]
5.
Kruziki MA; Case BA; Chan JY; Zudock EJ; Woldring DR; Yee D; Hackel BJ
Mol Pharm; 2016 Nov; 13(11):3747-3755. PubMed ID: 27696863
[TBL] [Abstract][Full Text] [Related]
6. Rational optimization of a bispecific ligand trap targeting EGF receptor family ligands.
Jin P; Zhang J; Beryt M; Turin L; Brdlik C; Feng Y; Bai X; Liu J; Jorgensen B; Shepard HM
Mol Med; 2009; 15(1-2):11-20. PubMed ID: 19048033
[TBL] [Abstract][Full Text] [Related]
7. Directed evolution to re-adapt a co-evolved network within an enzyme.
Strafford J; Payongsri P; Hibbert EG; Morris P; Batth SS; Steadman D; Smith ME; Ward JM; Hailes HC; Dalby PA
J Biotechnol; 2012 Jan; 157(1):237-45. PubMed ID: 22154561
[TBL] [Abstract][Full Text] [Related]
8. Biochemical properties of site-directed mutants of human epidermal growth factor: importance of solvent-exposed hydrophobic residues of the amino-terminal domain in receptor binding.
Campion SR; Matsunami RK; Engler DA; Niyogi SK
Biochemistry; 1990 Oct; 29(42):9988-93. PubMed ID: 2271634
[TBL] [Abstract][Full Text] [Related]
9. Constrained Combinatorial Libraries of Gp2 Proteins Enhance Discovery of PD-L1 Binders.
Kruziki MA; Sarma V; Hackel BJ
ACS Comb Sci; 2018 Jul; 20(7):423-435. PubMed ID: 29799714
[TBL] [Abstract][Full Text] [Related]
10. EGFR extracellular domain III expressed in Escherichia coli with SEP tag shows improved biophysical and functional properties and generate anti-sera inhibiting cancer cell growth.
Brindha S; Kibria MG; Saotome T; Unzai S; Kuroda Y
Biochem Biophys Res Commun; 2021 May; 555():121-127. PubMed ID: 33813270
[TBL] [Abstract][Full Text] [Related]
11. Computational tools help improve protein stability but with a solubility tradeoff.
Broom A; Jacobi Z; Trainor K; Meiering EM
J Biol Chem; 2017 Sep; 292(35):14349-14361. PubMed ID: 28710274
[TBL] [Abstract][Full Text] [Related]
12. Functional expression of a plant hydroxynitrile lyase in Escherichia coli by directed evolution: creation and characterization of highly in vivo soluble mutants.
Asano Y; Dadashipour M; Yamazaki M; Doi N; Komeda H
Protein Eng Des Sel; 2011 Aug; 24(8):607-16. PubMed ID: 21729945
[TBL] [Abstract][Full Text] [Related]
13. Engineering of recombinant human Fcγ receptor I by directed evolution.
Asaoka Y; Hatayama K; Tsumoto K; Tomita M; Ide T
Protein Eng Des Sel; 2012 Dec; 25(12):835-42. PubMed ID: 22967788
[TBL] [Abstract][Full Text] [Related]
14. The DNA binding domain of the gene 2.5 single-stranded DNA-binding protein of bacteriophage T7.
Hyland EM; Rezende LF; Richardson CC
J Biol Chem; 2003 Feb; 278(9):7247-56. PubMed ID: 12496273
[TBL] [Abstract][Full Text] [Related]
15. Design and assessment of an active anti-epidermal growth factor receptor (EGFR) single chain variable fragment (ScFv) with improved solubility.
Nautiyal K; Kibria MG; Akazawa-Ogawa Y; Hagihara Y; Kuroda Y
Biochem Biophys Res Commun; 2019 Jan; 508(4):1043-1049. PubMed ID: 30551882
[TBL] [Abstract][Full Text] [Related]
16. Synthetic and natural consensus design for engineering charge within an affibody targeting epidermal growth factor receptor.
Case BA; Hackel BJ
Biotechnol Bioeng; 2016 Aug; 113(8):1628-38. PubMed ID: 26724421
[TBL] [Abstract][Full Text] [Related]
17. Identification of two new hydrophobic residues on basic fibroblast growth factor important for fibroblast growth factor receptor binding.
Zhu H; Ramnarayan K; Menzel P; Miao Y; Zheng J; Mong S
Protein Eng; 1998 Oct; 11(10):937-40. PubMed ID: 9862214
[TBL] [Abstract][Full Text] [Related]
18. The extracellular domain of the epidermal growth factor receptor. Studies on the affinity and stoichiometry of binding, receptor dimerization and a binding-domain mutant.
Brown PM; Debanne MT; Grothe S; Bergsma D; Caron M; Kay C; O'Connor-McCourt MD
Eur J Biochem; 1994 Oct; 225(1):223-33. PubMed ID: 7925442
[TBL] [Abstract][Full Text] [Related]
19. Directed evolution and structural analysis of N-carbamoyl-D-amino acid amidohydrolase provide insights into recombinant protein solubility in Escherichia coli.
Jiang S; Li C; Zhang W; Cai Y; Yang Y; Yang S; Jiang W
Biochem J; 2007 Mar; 402(3):429-37. PubMed ID: 17121498
[TBL] [Abstract][Full Text] [Related]
20. Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach.
P S; D TK; C GPD; R S; Zayed H
PLoS One; 2017; 12(4):e0174953. PubMed ID: 28410371
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]