BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

374 related articles for article (PubMed ID: 30543818)

  • 1. Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies.
    Legrand F; Cao Y; Wechsler JB; Zhu X; Zimmermann N; Rampertaap S; Monsale J; Romito K; Youngblood BA; Brock EC; Makiya MA; Tomasevic N; Bebbington C; Maric I; Metcalfe DD; Bochner BS; Klion AD
    J Allergy Clin Immunol; 2019 Jun; 143(6):2227-2237.e10. PubMed ID: 30543818
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation.
    Kano G; Almanan M; Bochner BS; Zimmermann N
    J Allergy Clin Immunol; 2013 Aug; 132(2):437-45. PubMed ID: 23684072
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An anti-siglec-8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells.
    Kerr SC; Gonzalez JR; Schanin J; Peters MC; Lambrecht BN; Brock EC; Charbit A; Ansel KM; Youngblood BA; Fahy JV
    Clin Exp Allergy; 2020 Aug; 50(8):904-914. PubMed ID: 32542913
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Siglec-7 on peripheral blood eosinophils: Surface expression and function.
    Legrand F; Landolina N; Zaffran I; Emeh RO; Chen E; Klion AD; Levi-Schaffer F
    Allergy; 2019 Jul; 74(7):1257-1265. PubMed ID: 30690753
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
    Youngblood BA; Brock EC; Leung J; Falahati R; Bryce PJ; Bright J; Williams J; Shultz LD; Greiner DL; Brehm MA; Bebbington C; Tomasevic N
    Int Arch Allergy Immunol; 2019; 180(2):91-102. PubMed ID: 31401630
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β
    Carroll DJ; O'Sullivan JA; Nix DB; Cao Y; Tiemeyer M; Bochner BS
    J Allergy Clin Immunol; 2018 Jun; 141(6):2196-2207. PubMed ID: 28888781
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells.
    O'Sullivan JA; Carroll DJ; Cao Y; Salicru AN; Bochner BS
    J Allergy Clin Immunol; 2018 May; 141(5):1774-1785.e7. PubMed ID: 28734845
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): a novel therapeutic target for eosinophilic disorders.
    Legrand F; Tomasevic N; Simakova O; Lee CC; Wang Z; Raffeld M; Makiya MA; Palath V; Leung J; Baer M; Yarranton G; Maric I; Bebbington C; Klion AD
    J Allergy Clin Immunol; 2014 May; 133(5):1439-47, 1447.e1-8. PubMed ID: 24530099
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis.
    Youngblood BA; Brock EC; Leung J; Falahati R; Bochner BS; Rasmussen HS; Peterson K; Bebbington C; Tomasevic N
    JCI Insight; 2019 Oct; 4(19):. PubMed ID: 31465299
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Developmental, malignancy-related, and cross-species analysis of eosinophil, mast cell, and basophil siglec-8 expression.
    Hudson SA; Herrmann H; Du J; Cox P; Haddad el-B; Butler B; Crocker PR; Ackerman SJ; Valent P; Bochner BS
    J Clin Immunol; 2011 Dec; 31(6):1045-53. PubMed ID: 21938510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies.
    von Gunten S; Vogel M; Schaub A; Stadler BM; Miescher S; Crocker PR; Simon HU
    J Allergy Clin Immunol; 2007 Apr; 119(4):1005-11. PubMed ID: 17337295
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death
    Carroll DJ; Cao Y; Bochner BS; O'Sullivan JA
    Front Immunol; 2021; 12():737988. PubMed ID: 34721399
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery, Function, and Therapeutic Targeting of Siglec-8.
    Youngblood BA; Leung J; Falahati R; Williams J; Schanin J; Brock EC; Singh B; Chang AT; O'Sullivan JA; Schleimer RP; Tomasevic N; Bebbington CR; Bochner BS
    Cells; 2020 Dec; 10(1):. PubMed ID: 33374255
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils.
    Na HJ; Hudson SA; Bochner BS
    Cytokine; 2012 Jan; 57(1):169-74. PubMed ID: 22079334
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases.
    Kano G; Bochner BS; Zimmermann N
    Immunobiology; 2017 Feb; 222(2):343-349. PubMed ID: 27682013
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frontline Science: Characterization of a novel mouse strain expressing human Siglec-8 only on eosinophils.
    O'Sullivan JA; Wei Y; Carroll DJ; Moreno-Vinasco L; Cao Y; Zhang F; Lee JJ; Zhu Z; Bochner BS
    J Leukoc Biol; 2018 Jul; 104(1):11-19. PubMed ID: 29601103
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily.
    Floyd H; Ni J; Cornish AL; Zeng Z; Liu D; Carter KC; Steel J; Crocker PR
    J Biol Chem; 2000 Jan; 275(2):861-6. PubMed ID: 10625619
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interleukin-5 priming of human eosinophils alters siglec-8 mediated apoptosis pathways.
    Nutku-Bilir E; Hudson SA; Bochner BS
    Am J Respir Cell Mol Biol; 2008 Jan; 38(1):121-4. PubMed ID: 17690326
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis.
    Nutku E; Aizawa H; Hudson SA; Bochner BS
    Blood; 2003 Jun; 101(12):5014-20. PubMed ID: 12609831
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody.
    Gebremeskel S; Schanin J; Coyle KM; Butuci M; Luu T; Brock EC; Xu A; Wong A; Leung J; Korver W; Morin RD; Schleimer RP; Bochner BS; Youngblood BA
    Front Immunol; 2021; 12():650331. PubMed ID: 33777047
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.