BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 30548204)

  • 1. Chemical Space Overlap with Critical Protein-Protein Interface Residues in Commercial and Specialized Small-Molecule Libraries.
    Si Y; Xu D; Bum-Erdene K; Ghozayel MK; Yang B; Clemons PA; Meroueh SO
    ChemMedChem; 2019 Jan; 14(1):119-131. PubMed ID: 30548204
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mimicking Intermolecular Interactions of Tight Protein-Protein Complexes for Small-Molecule Antagonists.
    Xu D; Bum-Erdene K; Si Y; Zhou D; Ghozayel MK; Meroueh SO
    ChemMedChem; 2017 Nov; 12(21):1794-1809. PubMed ID: 28960868
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small Molecules Engage Hot Spots through Cooperative Binding To Inhibit a Tight Protein-Protein Interaction.
    Liu D; Xu D; Liu M; Knabe WE; Yuan C; Zhou D; Huang M; Meroueh SO
    Biochemistry; 2017 Mar; 56(12):1768-1784. PubMed ID: 28186725
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.
    Bier D; Bartel M; Sies K; Halbach S; Higuchi Y; Haranosono Y; Brummer T; Kato N; Ottmann C
    ChemMedChem; 2016 Apr; 11(8):911-8. PubMed ID: 26644359
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A new class of orthosteric uPAR·uPA small-molecule antagonists are allosteric inhibitors of the uPAR·vitronectin interaction.
    Liu D; Zhou D; Wang B; Knabe WE; Meroueh SO
    ACS Chem Biol; 2015 Jun; 10(6):1521-34. PubMed ID: 25671694
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction.
    Bum-Erdene K; Zhou D; Gonzalez-Gutierrez G; Ghozayel MK; Si Y; Xu D; Shannon HE; Bailey BJ; Corson TW; Pollok KE; Wells CD; Meroueh SO
    Cell Chem Biol; 2019 Mar; 26(3):378-389.e13. PubMed ID: 30581134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and ligand-binding analysis of the YAP-binding domain of transcription factor TEAD4.
    Li Y; Liu S; Ng EY; Li R; Poulsen A; Hill J; Pobbati AV; Hung AW; Hong W; Keller TH; Kang C
    Biochem J; 2018 Jun; 475(12):2043-2055. PubMed ID: 29760238
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence.
    Furet P; Salem B; Mesrouze Y; Schmelzle T; Lewis I; Kallen J; Chène P
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2316-2319. PubMed ID: 31235263
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small-Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection.
    Xu D; Bum-Erdene K; Leth JM; Ghozayel MK; Ploug M; Meroueh SO
    ChemMedChem; 2021 Jan; 16(2):377-387. PubMed ID: 33107192
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hot spot-based design of small-molecule inhibitors for protein-protein interactions.
    Guo W; Wisniewski JA; Ji H
    Bioorg Med Chem Lett; 2014 Jun; 24(11):2546-54. PubMed ID: 24751445
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of the acylation of TEAD4 on its interaction with co-activators YAP and TAZ.
    Mesrouze Y; Meyerhofer M; Bokhovchuk F; Fontana P; Zimmermann C; Martin T; Delaunay C; Izaac A; Kallen J; Schmelzle T; Erdmann D; Chène P
    Protein Sci; 2017 Dec; 26(12):2399-2409. PubMed ID: 28960584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Natural products used as a chemical library for protein-protein interaction targeted drug discovery.
    Jin X; Lee K; Kim NH; Kim HS; Yook JI; Choi J; No KT
    J Mol Graph Model; 2018 Jan; 79():46-58. PubMed ID: 29136547
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quinoline-based Protein-protein Interaction Inhibitors of LEDGF/p75 and HIV Integrase: An In Silico Study.
    Chhokar N; Kalra S; Chauhan M; Munshi A; Kumar R
    Curr Top Med Chem; 2018; 18(32):2800-2815. PubMed ID: 30747071
    [TBL] [Abstract][Full Text] [Related]  

  • 14. State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.
    Sheng C; Dong G; Miao Z; Zhang W; Wang W
    Chem Soc Rev; 2015 Nov; 44(22):8238-59. PubMed ID: 26248294
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival.
    Vilaboa N; Boré A; Martin-Saavedra F; Bayford M; Winfield N; Firth-Clark S; Kirton SB; Voellmy R
    Nucleic Acids Res; 2017 Jun; 45(10):5797-5817. PubMed ID: 28369544
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benchmark Study Based on 2P2I
    Wang Z; Kang Y; Li D; Sun H; Dong X; Yao X; Xu L; Chang S; Li Y; Hou T
    J Phys Chem B; 2018 Mar; 122(9):2544-2555. PubMed ID: 29420886
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rational design of selective small-molecule inhibitors for β-catenin/B-cell lymphoma 9 protein-protein interactions.
    Hoggard LR; Zhang Y; Zhang M; Panic V; Wisniewski JA; Ji H
    J Am Chem Soc; 2015 Sep; 137(38):12249-60. PubMed ID: 26352795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Computational Investigation of Small-Molecule Engagement of Hot Spots at Protein-Protein Interaction Interfaces.
    Xu D; Si Y; Meroueh SO
    J Chem Inf Model; 2017 Sep; 57(9):2250-2272. PubMed ID: 28766941
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In silico structure-based approaches to discover protein-protein interaction-targeting drugs.
    Shin WH; Christoffer CW; Kihara D
    Methods; 2017 Dec; 131():22-32. PubMed ID: 28802714
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small-molecule inhibition of the uPAR·uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis.
    Mani T; Wang F; Knabe WE; Sinn AL; Khanna M; Jo I; Sandusky GE; Sledge GW; Jones DR; Khanna R; Pollok KE; Meroueh SO
    Bioorg Med Chem; 2013 Apr; 21(7):2145-55. PubMed ID: 23411397
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.