BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 30548446)

  • 41. Telmisartan attenuates MPTP induced dopaminergic degeneration and motor dysfunction through regulation of α-synuclein and neurotrophic factors (BDNF and GDNF) expression in C57BL/6J mice.
    Sathiya S; Ranju V; Kalaivani P; Priya RJ; Sumathy H; Sunil AG; Babu CS
    Neuropharmacology; 2013 Oct; 73():98-110. PubMed ID: 23747572
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Rab1A over-expression prevents Golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinson's disease.
    Coune PG; Bensadoun JC; Aebischer P; Schneider BL
    J Parkinsons Dis; 2011; 1(4):373-87. PubMed ID: 23939344
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Relationship among alpha-synuclein accumulation, dopamine synthesis, and neurodegeneration in Parkinson disease substantia nigra.
    Mori F; Nishie M; Kakita A; Yoshimoto M; Takahashi H; Wakabayashi K
    J Neuropathol Exp Neurol; 2006 Aug; 65(8):808-15. PubMed ID: 16896314
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Modelling cognitive deficits in Parkinson's disease: Is CA2 a gateway for hippocampal synucleinopathy?
    Cinar E; Yalcin-Cakmakli G; Saka E; Ulusoy A; Yuruker S; Elibol B; Tel BC
    Exp Neurol; 2020 Aug; 330():113357. PubMed ID: 32437708
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease.
    Koprich JB; Johnston TH; Reyes MG; Sun X; Brotchie JM
    Mol Neurodegener; 2010 Oct; 5():43. PubMed ID: 21029459
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra.
    von Bohlen und Halbach O; Minichiello L; Unsicker K
    FASEB J; 2005 Oct; 19(12):1740-2. PubMed ID: 16037097
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity.
    Gaugler MN; Genc O; Bobela W; Mohanna S; Ardah MT; El-Agnaf OM; Cantoni M; Bensadoun JC; Schneggenburger R; Knott GW; Aebischer P; Schneider BL
    Acta Neuropathol; 2012 May; 123(5):653-69. PubMed ID: 22361813
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Reduction of alpha-synuclein oligomers in preclinical models of Parkinson's disease by electrical stimulation in vitro and deep brain stimulation in vivo.
    Lee EJ; Aguirre-Padilla DH; Fomenko A; Pawar G; Kapadia M; George J; Lozano AM; Hamani C; Kalia LV; Kalia SK
    Brain Stimul; 2024; 17(2):166-175. PubMed ID: 38342364
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
    Paumier KL; Luk KC; Manfredsson FP; Kanaan NM; Lipton JW; Collier TJ; Steece-Collier K; Kemp CJ; Celano S; Schulz E; Sandoval IM; Fleming S; Dirr E; Polinski NK; Trojanowski JQ; Lee VM; Sortwell CE
    Neurobiol Dis; 2015 Oct; 82():185-199. PubMed ID: 26093169
    [TBL] [Abstract][Full Text] [Related]  

  • 50. α-Synuclein overexpression impairs mitochondrial function by associating with adenylate translocator.
    Zhu Y; Duan C; Lü L; Gao H; Zhao C; Yu S; Uéda K; Chan P; Yang H
    Int J Biochem Cell Biol; 2011 May; 43(5):732-41. PubMed ID: 21310263
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Long-term RNAi knockdown of α-synuclein in the adult rat substantia nigra without neurodegeneration.
    Zharikov A; Bai Q; De Miranda BR; Van Laar A; Greenamyre JT; Burton EA
    Neurobiol Dis; 2019 May; 125():146-153. PubMed ID: 30658149
    [TBL] [Abstract][Full Text] [Related]  

  • 52. In vivo RNAi-mediated alpha-synuclein silencing induces nigrostriatal degeneration.
    Gorbatyuk OS; Li S; Nash K; Gorbatyuk M; Lewin AS; Sullivan LF; Mandel RJ; Chen W; Meyers C; Manfredsson FP; Muzyczka N
    Mol Ther; 2010 Aug; 18(8):1450-7. PubMed ID: 20551914
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Potential neuroprotective effect of androst-5-ene-3β, 17β-diol (ADIOL) on the striatum, and substantia nigra in Parkinson's disease rat model.
    Salama RM; Tadros MG; Schaalan MF; Bahaa N; Abdel-Tawab AM; Khalifa AE
    J Cell Physiol; 2018 Aug; 233(8):5981-6000. PubMed ID: 29266208
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD.
    Hoban DB; Shrigley S; Mattsson B; Breger LS; Jarl U; Cardoso T; Nelander Wahlestedt J; Luk KC; Björklund A; Parmar M
    Proc Natl Acad Sci U S A; 2020 Jun; 117(26):15209-15220. PubMed ID: 32541058
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Glucose regulated protein 78 diminishes α-synuclein neurotoxicity in a rat model of Parkinson disease.
    Gorbatyuk MS; Shabashvili A; Chen W; Meyers C; Sullivan LF; Salganik M; Lin JH; Lewin AS; Muzyczka N; Gorbatyuk OS
    Mol Ther; 2012 Jul; 20(7):1327-37. PubMed ID: 22434142
    [TBL] [Abstract][Full Text] [Related]  

  • 56. α-Synuclein Expression Is Preserved in Substantia Nigra GABAergic Fibers of Young and Aged Neurotoxin-Treated Rhesus Monkeys.
    Vermilyea SC; Guthrie S; Hernandez I; Bondarenko V; Emborg ME
    Cell Transplant; 2019 Apr; 28(4):379-387. PubMed ID: 30857404
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Interaction between subclinical doses of the Parkinson's disease associated gene, α-synuclein, and the pesticide, rotenone, precipitates motor dysfunction and nigrostriatal neurodegeneration in rats.
    Naughton C; O'Toole D; Kirik D; Dowd E
    Behav Brain Res; 2017 Jan; 316():160-168. PubMed ID: 27585560
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Voltage-dependent anion channel involved in the α-synuclein-induced dopaminergic neuron toxicity in rats.
    Lu L; Zhang C; Cai Q; Lu Q; Duan C; Zhu Y; Yang H
    Acta Biochim Biophys Sin (Shanghai); 2013 Mar; 45(3):170-8. PubMed ID: 23291291
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.
    Caudal D; Alvarsson A; Björklund A; Svenningsson P
    Exp Neurol; 2015 Nov; 273():243-52. PubMed ID: 26363495
    [TBL] [Abstract][Full Text] [Related]  

  • 60. GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson's Disease.
    Schneider JS; Aras R; Williams CK; Koprich JB; Brotchie JM; Singh V
    Sci Rep; 2019 Jun; 9(1):8362. PubMed ID: 31182727
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.