181 related articles for article (PubMed ID: 30554957)
1. Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M
Lee NR; Gujarathi S; Bommagani S; Siripurapu K; Zheng G; Dwoskin LP
Bioorg Med Chem Lett; 2019 Feb; 29(3):471-476. PubMed ID: 30554957
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and pharmacological evaluation of dimeric muscarinic acetylcholine receptor agonists.
Christopoulos A; Grant MK; Ayoubzadeh N; Kim ON; Sauerberg P; Jeppesen L; El-Fakahany EE
J Pharmacol Exp Ther; 2001 Sep; 298(3):1260-8. PubMed ID: 11504829
[TBL] [Abstract][Full Text] [Related]
3. Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice.
Zhang W; Yamada M; Gomeza J; Basile AS; Wess J
J Neurosci; 2002 Aug; 22(15):6347-52. PubMed ID: 12151512
[TBL] [Abstract][Full Text] [Related]
4. Effects of muscarinic toxins MT2 and MT7, from green mamba venom, on m1, m3 and m5 muscarinic receptors expressed in Chinese Hamster Ovary cells.
Bradley KN; Rowan EG; Harvey AL
Toxicon; 2003 Feb; 41(2):207-15. PubMed ID: 12565740
[TBL] [Abstract][Full Text] [Related]
5. Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments.
Del Bello F; Bonifazi A; Giorgioni G; Petrelli R; Quaglia W; Altomare A; Falcicchio A; Matucci R; Vistoli G; Piergentili A
Eur J Med Chem; 2017 Sep; 137():327-337. PubMed ID: 28609709
[TBL] [Abstract][Full Text] [Related]
6. Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.
Jakubík J; Bacáková L; El-Fakahany EE; Tucek S
Mol Pharmacol; 1997 Jul; 52(1):172-9. PubMed ID: 9224827
[TBL] [Abstract][Full Text] [Related]
7. Discovery and structure-activity relationships study of positive allosteric modulators of the M
Tanaka H; Negoro K; Koike T; Tsukamoto I; Yokoyama K; Maeda J; Inagaki Y; Shimoshige Y; Ino K; Ishizu K; Takahashi T
Bioorg Med Chem; 2020 Jul; 28(13):115531. PubMed ID: 32386953
[TBL] [Abstract][Full Text] [Related]
8. Muscarinic acetylcholine receptor binding affinities of pethidine analogs.
Lee NR; Zhang X; Darna M; Dwoskin LP; Zheng G
Bioorg Med Chem Lett; 2015 Nov; 25(22):5032-5. PubMed ID: 26494260
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases.
Salmon M; Luttmann MA; Foley JJ; Buckley PT; Schmidt DB; Burman M; Webb EF; DeHaas CJ; Kotzer CJ; Barrett VJ; Slack RJ; Sarau HM; Palovich MR; Lainé DI; Hay DW; Rumsey WL
J Pharmacol Exp Ther; 2013 May; 345(2):260-70. PubMed ID: 23435542
[TBL] [Abstract][Full Text] [Related]
10. 6beta-Acetoxynortropane: a potent muscarinic agonist with apparent selectivity toward M2-receptors.
Pei XF; Gupta TH; Badio B; Padgett WL; Daly JW
J Med Chem; 1998 Jun; 41(12):2047-55. PubMed ID: 9622546
[TBL] [Abstract][Full Text] [Related]
11. Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors.
Bräuner-Osborne H; Ebert B; Brann MR; Falch E; Krogsgaard-Larsen P
J Med Chem; 1995 Jun; 38(12):2188-95. PubMed ID: 7783150
[TBL] [Abstract][Full Text] [Related]
12. SB 202026: a novel muscarinic partial agonist with functional selectivity for M1 receptors.
Loudon JM; Bromidge SM; Brown F; Clark MS; Hatcher JP; Hawkins J; Riley GJ; Noy G; Orlek BS
J Pharmacol Exp Ther; 1997 Dec; 283(3):1059-68. PubMed ID: 9399977
[TBL] [Abstract][Full Text] [Related]
13. Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1.
Langmead CJ; Austin NE; Branch CL; Brown JT; Buchanan KA; Davies CH; Forbes IT; Fry VA; Hagan JJ; Herdon HJ; Jones GA; Jeggo R; Kew JN; Mazzali A; Melarange R; Patel N; Pardoe J; Randall AD; Roberts C; Roopun A; Starr KR; Teriakidis A; Wood MD; Whittington M; Wu Z; Watson J
Br J Pharmacol; 2008 Jul; 154(5):1104-15. PubMed ID: 18454168
[TBL] [Abstract][Full Text] [Related]
14. The interaction of the enantiomers of aceclidine with subtypes of the muscarinic receptor.
Ehlert FJ; Griffin MT; Glidden PF
J Pharmacol Exp Ther; 1996 Dec; 279(3):1335-44. PubMed ID: 8968358
[TBL] [Abstract][Full Text] [Related]
15. Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors.
Jakubík J; Bacáková L; el-Fakahany EE; Tucek S
J Pharmacol Exp Ther; 1995 Sep; 274(3):1077-83. PubMed ID: 7562472
[TBL] [Abstract][Full Text] [Related]
16. 6beta-Acyloxy(nor)tropanes: affinities for antagonist/agonist binding sites on transfected and native muscarinic receptors.
Daly JW; Gupta TH; Padgett WL; Pei XF
J Med Chem; 2000 Jun; 43(13):2514-22. PubMed ID: 10891110
[TBL] [Abstract][Full Text] [Related]
17. Activation of cerebral function by CS-932, a functionally selective M1 partial agonist: neurochemical characterization and pharmacological studies.
Iwata N; Kozuka M; Hara T; Kanek T; Tonohiro T; Sugimoto M; Niitsu Y; Kondo Y; Yamamoto T; Sakai J; Nagano M
Jpn J Pharmacol; 2000 Nov; 84(3):266-80. PubMed ID: 11138727
[TBL] [Abstract][Full Text] [Related]
18. Structural modifications to tetrahydropyridine-3-carboxylate esters en route to the discovery of M5-preferring muscarinic receptor orthosteric antagonists.
Zheng G; Smith AM; Huang X; Subramanian KL; Siripurapu KB; Deaciuc A; Zhan CG; Dwoskin LP
J Med Chem; 2013 Feb; 56(4):1693-703. PubMed ID: 23379472
[TBL] [Abstract][Full Text] [Related]
19. Structural Features of Iperoxo-BQCA Muscarinic Acetylcholine Receptor Hybrid Ligands Determining Subtype Selectivity and Efficacy.
Wakeham MCL; Davie BJ; Chalmers DK; Christopoulos A; Capuano B; Valant C; Scammells PJ
ACS Chem Neurosci; 2022 Jan; 13(1):97-111. PubMed ID: 34905693
[TBL] [Abstract][Full Text] [Related]
20. New insight into active muscarinic receptors with the novel radioagonist [³H]iperoxo.
Schrage R; Holze J; Klöckner J; Balkow A; Klause AS; Schmitz AL; De Amici M; Kostenis E; Tränkle C; Holzgrabe U; Mohr K
Biochem Pharmacol; 2014 Aug; 90(3):307-19. PubMed ID: 24863257
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]