These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 30556867)

  • 1. MRFAP1 plays a protective role in neddylation inhibitor MLN4924-mediated gastric cancer cell death.
    Hu L; Bai ZG; Ma XM; Bai N; Zhang ZT
    Eur Rev Med Pharmacol Sci; 2018 Dec; 22(23):8273-8280. PubMed ID: 30556867
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
    Lan H; Tang Z; Jin H; Sun Y
    Sci Rep; 2016 Apr; 6():24218. PubMed ID: 27063292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The novel protective role of P27 in MLN4924-treated gastric cancer cells.
    Zhang Q; Hou D; Luo Z; Chen P; Lv B; Wu L; Ma Y; Chu Y; Liu H; Liu F; Yu S; Zhang J; Yang D; Liu J
    Cell Death Dis; 2015 Aug; 6(8):e1867. PubMed ID: 26313918
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A first-in-class inhibitor, MLN4924 (pevonedistat), induces cell-cycle arrest, senescence, and apoptosis in human renal cell carcinoma by suppressing UBE2M-dependent neddylation modification.
    Xu B; Deng Y; Bi R; Guo H; Shu C; Shah NK; Chang J; Liu G; Du Y; Wei W; Wang C
    Cancer Chemother Pharmacol; 2018 Jun; 81(6):1083-1093. PubMed ID: 29667067
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
    Yao WT; Wu JF; Yu GY; Wang R; Wang K; Li LH; Chen P; Jiang YN; Cheng H; Lee HW; Yu J; Qi H; Yu XJ; Wang P; Chu YW; Yang M; Hua ZC; Ying HQ; Hoffman RM; Jeong LS; Jia LJ
    Cell Death Dis; 2014 Feb; 5(2):e1059. PubMed ID: 24525735
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neddylation inhibition activates the protective autophagy through NF-κB-catalase-ATF3 Axis in human esophageal cancer cells.
    Liang Y; Jiang Y; Jin X; Chen P; Heng Y; Cai L; Zhang W; Li L; Jia L
    Cell Commun Signal; 2020 May; 18(1):72. PubMed ID: 32398095
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924.
    Liao H; Liu XJ; Blank JL; Bouck DC; Bernard H; Garcia K; Lightcap ES
    Mol Cell Proteomics; 2011 Nov; 10(11):M111.009183. PubMed ID: 21873567
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcoma.
    Zhang Y; Shi CC; Zhang HP; Li GQ; Li SS
    Oncotarget; 2016 Jul; 7(29):45263-45274. PubMed ID: 27223074
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neddylation pathway regulates the proliferation and survival of macrophages.
    Li L; Liu B; Dong T; Lee HW; Yu J; Zheng Y; Gao H; Zhang Y; Chu Y; Liu G; Niu W; Zheng S; Jeong LS; Jia L
    Biochem Biophys Res Commun; 2013 Mar; 432(3):494-8. PubMed ID: 23416079
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.
    Larance M; Kirkwood KJ; Xirodimas DP; Lundberg E; Uhlen M; Lamond AI
    Mol Cell Proteomics; 2012 Mar; 11(3):M111.014407. PubMed ID: 22038470
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of p21-dependent senescence by an NAE inhibitor, MLN4924, as a mechanism of growth suppression.
    Jia L; Li H; Sun Y
    Neoplasia; 2011 Jun; 13(6):561-9. PubMed ID: 21677879
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer.
    Pan WW; Zhou JJ; Yu C; Xu Y; Guo LJ; Zhang HY; Zhou D; Song FZ; Fan HY
    J Biol Chem; 2013 Oct; 288(41):29680-91. PubMed ID: 23995842
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells.
    Wang Y; Luo Z; Pan Y; Wang W; Zhou X; Jeong LS; Chu Y; Liu J; Jia L
    Cancer Biol Ther; 2015; 16(3):420-9. PubMed ID: 25782162
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma.
    Tong S; Si Y; Yu H; Zhang L; Xie P; Jiang W
    Sci Rep; 2017 Jul; 7(1):5599. PubMed ID: 28717191
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AKT inhibitor MK-2206 sensitizes breast cancer cells to MLN4924, a first-in-class NEDD8-activating enzyme (NAE) inhibitor.
    Chen X; Cui D; Bi Y; Shu J; Xiong X; Zhao Y
    Cell Cycle; 2018; 17(16):2069-2079. PubMed ID: 30198810
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme inhibitor pevonedistat (MLN4924).
    Wong KM; Micel LN; Selby HM; Tan AC; Pitts TM; Bagby SM; Spreafico A; Klauck PJ; Blakemore SJ; Smith PF; McDonald A; Berger A; Tentler JJ; Eckhardt SG
    Invest New Drugs; 2017 Feb; 35(1):11-25. PubMed ID: 27783255
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NF-κB activation and induces apoptosis in chronic lymphocytic leukemia B cells.
    Godbersen JC; Humphries LA; Danilova OV; Kebbekus PE; Brown JR; Eastman A; Danilov AV
    Clin Cancer Res; 2014 Mar; 20(6):1576-89. PubMed ID: 24634471
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis.
    Wu MH; Lee CY; Huang TJ; Huang KY; Tang CH; Liu SH; Kuo KL; Kuan FC; Lin WC; Shi CS
    Int J Mol Sci; 2018 Dec; 20(1):. PubMed ID: 30586948
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neddylation Inactivation Facilitates FOXO3a Nuclear Export to Suppress Estrogen Receptor Transcription and Improve Fulvestrant Sensitivity.
    Jia X; Li C; Li L; Liu X; Zhou L; Zhang W; Ni S; Lu Y; Chen L; Jeong LS; Yu J; Zhang Y; Zhang J; He S; Hu X; Sun H; Yu K; Liu G; Zhao H; Zhang Y; Jia L; Shao ZM
    Clin Cancer Res; 2019 Jun; 25(12):3658-3672. PubMed ID: 30833270
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nedd8-activating enzyme inhibitor MLN4924 (Pevonedistat), inhibits miR-1303 to suppress human breast cancer cell proliferation via targeting p27
    Chen Y; Du M; Yusuying S; Liu W; Tan Y; Xie P
    Exp Cell Res; 2020 Jul; 392(2):112038. PubMed ID: 32360865
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.