These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

433 related articles for article (PubMed ID: 30558232)

  • 21. MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.
    Hoch L; Faure H; Roudaut H; Schoenfelder A; Mann A; Girard N; Bihannic L; Ayrault O; Petricci E; Taddei M; Rognan D; Ruat M
    FASEB J; 2015 May; 29(5):1817-29. PubMed ID: 25636740
    [TBL] [Abstract][Full Text] [Related]  

  • 22. NL-103, a novel dual-targeted inhibitor of histone deacetylases and hedgehog pathway, effectively overcomes vismodegib resistance conferred by Smo mutations.
    Zhao J; Quan H; Xie C; Lou L
    Pharmacol Res Perspect; 2014 Jun; 2(3):e00043. PubMed ID: 25505589
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Targeting GLI factors to inhibit the Hedgehog pathway.
    Infante P; Alfonsi R; Botta B; Mori M; Di Marcotullio L
    Trends Pharmacol Sci; 2015 Aug; 36(8):547-58. PubMed ID: 26072120
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Digging a hole under Hedgehog: downstream inhibition as an emerging anticancer strategy.
    Di Magno L; Coni S; Di Marcotullio L; Canettieri G
    Biochim Biophys Acta; 2015 Aug; 1856(1):62-72. PubMed ID: 26080084
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 26. ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli.
    Huang W; Liu H; Tan W; Wang J
    Med Oncol; 2022 Sep; 39(12):188. PubMed ID: 36071246
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.
    Lee H; Ko HW
    Biochem Biophys Res Commun; 2016 Nov; 480(4):574-579. PubMed ID: 27793670
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Hedgehog pathway as a drug target: Smoothened inhibitors in development.
    Lin TL; Matsui W
    Onco Targets Ther; 2012; 5():47-58. PubMed ID: 22500124
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
    Skoda AM; Simovic D; Karin V; Kardum V; Vranic S; Serman L
    Bosn J Basic Med Sci; 2018 Feb; 18(1):8-20. PubMed ID: 29274272
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer?
    Bhateja P; Cherian M; Majumder S; Ramaswamy B
    Cancers (Basel); 2019 Aug; 11(8):. PubMed ID: 31394751
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas.
    Jain S; Song R; Xie J
    Onco Targets Ther; 2017; 10():1645-1653. PubMed ID: 28352196
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Targeting GLI Transcription Factors in Cancer.
    Didiasova M; Schaefer L; Wygrecka M
    Molecules; 2018 Apr; 23(5):. PubMed ID: 29695137
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Hedgehog Pathway Inhibitors as Targeted Cancer Therapy and Strategies to Overcome Drug Resistance.
    Nguyen NM; Cho J
    Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163655
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification and mechanism of action of the acylguanidine MRT-83, a novel potent Smoothened antagonist.
    Roudaut H; Traiffort E; Gorojankina T; Vincent L; Faure H; Schoenfelder A; Mann A; Manetti F; Solinas A; Taddei M; Ruat M
    Mol Pharmacol; 2011 Mar; 79(3):453-60. PubMed ID: 21177415
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Structural optimization on a virtual screening hit of smoothened receptor.
    Song S; Jiang J; Zhao L; Wang Q; Lu W; Zheng C; Zhang J; Ma H; Tian S; Zheng J; Luo L; Li Y; Yang ZJ; Zhang X
    Eur J Med Chem; 2019 Jun; 172():1-15. PubMed ID: 30939349
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma.
    Doan HQ; Chen L; Nawas Z; Lee HH; Silapunt S; Migden M
    Oncotarget; 2021 Sep; 12(20):2089-2100. PubMed ID: 34611482
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting of Smoothened for therapeutic gain.
    Ruat M; Hoch L; Faure H; Rognan D
    Trends Pharmacol Sci; 2014 May; 35(5):237-46. PubMed ID: 24703627
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A synthetic combinatorial approach to disabling deviant Hedgehog signaling.
    Fan CW; Yarravarapu N; Shi H; Kulak O; Kim J; Chen C; Lum L
    Sci Rep; 2018 Jan; 8(1):1133. PubMed ID: 29348431
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Regulation of Hedgehog Signaling in Cancer by Natural and Dietary Compounds.
    Bao C; Kramata P; Lee HJ; Suh N
    Mol Nutr Food Res; 2018 Jan; 62(1):. PubMed ID: 29164817
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib.
    Kumari A; Ermilov AN; Grachtchouk M; Dlugosz AA; Allen BL; Bradley RM; Mistretta CM
    Proc Natl Acad Sci U S A; 2017 Nov; 114(48):E10369-E10378. PubMed ID: 29133390
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.