197 related articles for article (PubMed ID: 30559292)
1. Disease-linked mutations in the phosphatidylcholine regulatory enzyme CCTα impair enzymatic activity and fold stability.
Cornell RB; Taneva SG; Dennis MK; Tse R; Dhillon RK; Lee J
J Biol Chem; 2019 Feb; 294(5):1490-1501. PubMed ID: 30559292
[TBL] [Abstract][Full Text] [Related]
2. Interdomain communication in the phosphatidylcholine regulatory enzyme, CCTα, relies on a modular αE helix.
Taneva SG; Lee J; Knowles DG; Tishyadhigama C; Chen H; Cornell RB
J Biol Chem; 2019 Oct; 294(42):15517-15530. PubMed ID: 31488547
[TBL] [Abstract][Full Text] [Related]
3. Mutations in PCYT1A, encoding a key regulator of phosphatidylcholine metabolism, cause spondylometaphyseal dysplasia with cone-rod dystrophy.
Hoover-Fong J; Sobreira N; Jurgens J; Modaff P; Blout C; Moser A; Kim OH; Cho TJ; Cho SY; Kim SJ; Jin DK; Kitoh H; Park WY; Ling H; Hetrick KN; Doheny KF; Valle D; Pauli RM
Am J Hum Genet; 2014 Jan; 94(1):105-12. PubMed ID: 24387990
[No Abstract] [Full Text] [Related]
4. Novel mutations in PCYT1A are responsible for spondylometaphyseal dysplasia with cone-rod dystrophy.
Wong CK
Clin Genet; 2014 Jun; 85(6):532-3. PubMed ID: 24476460
[No Abstract] [Full Text] [Related]
5. Crystal structure of a mammalian CTP: phosphocholine cytidylyltransferase catalytic domain reveals novel active site residues within a highly conserved nucleotidyltransferase fold.
Lee J; Johnson J; Ding Z; Paetzel M; Cornell RB
J Biol Chem; 2009 Nov; 284(48):33535-48. PubMed ID: 19783652
[TBL] [Abstract][Full Text] [Related]
6. CTP:phosphocholine cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure without affecting phosphatidylcholine synthesis.
Gehrig K; Ridgway ND
Biochim Biophys Acta; 2011 Jun; 1811(6):377-85. PubMed ID: 21504799
[TBL] [Abstract][Full Text] [Related]
7. Lipid activation of CTP: phosphocholine cytidylyltransferase alpha: characterization and identification of a second activation domain.
Lykidis A; Jackson P; Jackowski S
Biochemistry; 2001 Jan; 40(2):494-503. PubMed ID: 11148044
[TBL] [Abstract][Full Text] [Related]
8. A 22-mer segment in the structurally pliable regulatory domain of metazoan CTP: phosphocholine cytidylyltransferase facilitates both silencing and activating functions.
Ding Z; Taneva SG; Huang HK; Campbell SA; Semenec L; Chen N; Cornell RB
J Biol Chem; 2012 Nov; 287(46):38980-91. PubMed ID: 22988242
[TBL] [Abstract][Full Text] [Related]
9. The intrinsically disordered nuclear localization signal and phosphorylation segments distinguish the membrane affinity of two cytidylyltransferase isoforms.
Dennis MK; Taneva SG; Cornell RB
J Biol Chem; 2011 Apr; 286(14):12349-60. PubMed ID: 21303909
[TBL] [Abstract][Full Text] [Related]
10. Mutations in PCYT1A cause spondylometaphyseal dysplasia with cone-rod dystrophy.
Yamamoto GL; Baratela WA; Almeida TF; Lazar M; Afonso CL; Oyamada MK; Suzuki L; Oliveira LA; Ramos ES; Kim CA; Passos-Bueno MR; Bertola DR
Am J Hum Genet; 2014 Jan; 94(1):113-9. PubMed ID: 24387991
[TBL] [Abstract][Full Text] [Related]
11. Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase.
Lykidis A; Murti KG; Jackowski S
J Biol Chem; 1998 May; 273(22):14022-9. PubMed ID: 9593753
[TBL] [Abstract][Full Text] [Related]
12. Remodeling of the interdomain allosteric linker upon membrane binding of CCTα pulls its active site close to the membrane surface.
Knowles DG; Lee J; Taneva SG; Cornell RB
J Biol Chem; 2019 Oct; 294(42):15531-15543. PubMed ID: 31488548
[TBL] [Abstract][Full Text] [Related]
13. Mutations in the PCYT1A gene are responsible for isolated forms of retinal dystrophy.
Testa F; Filippelli M; Brunetti-Pierri R; Di Fruscio G; Di Iorio V; Pizzo M; Torella A; Barillari MR; Nigro V; Brunetti-Pierri N; Simonelli F; Banfi S
Eur J Hum Genet; 2017 May; 25(5):651-655. PubMed ID: 28272537
[TBL] [Abstract][Full Text] [Related]
14. Regulation of CTP:phosphocholine cytidylyltransferase by amphitropism and relocalization.
Cornell RB; Northwood IC
Trends Biochem Sci; 2000 Sep; 25(9):441-7. PubMed ID: 10973058
[TBL] [Abstract][Full Text] [Related]
15. Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a).
Wang L; Magdaleno S; Tabas I; Jackowski S
Mol Cell Biol; 2005 Apr; 25(8):3357-63. PubMed ID: 15798219
[TBL] [Abstract][Full Text] [Related]
16. Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain.
Gehrig K; Morton CC; Ridgway ND
J Lipid Res; 2009 May; 50(5):966-76. PubMed ID: 19098306
[TBL] [Abstract][Full Text] [Related]
17. Functions of membrane binding domain of CTP:phosphocholine cytidylyltransferase in alveolar type II cells.
Ridsdale R; Tseu I; Wang J; Post M
Am J Respir Cell Mol Biol; 2010 Jul; 43(1):74-87. PubMed ID: 19684306
[TBL] [Abstract][Full Text] [Related]
18. Oxidized lipoproteins inhibit surfactant phosphatidylcholine synthesis via calpain-mediated cleavage of CTP:phosphocholine cytidylyltransferase.
Zhou J; Ryan AJ; Medh J; Mallampalli RK
J Biol Chem; 2003 Sep; 278(39):37032-40. PubMed ID: 12857760
[TBL] [Abstract][Full Text] [Related]
19. Enzymatic and cellular characterization of a catalytic fragment of CTP:phosphocholine cytidylyltransferase alpha.
Friesen JA; Campbell HA; Kent C
J Biol Chem; 1999 May; 274(19):13384-9. PubMed ID: 10224101
[TBL] [Abstract][Full Text] [Related]
20. Interdomain and membrane interactions of CTP:phosphocholine cytidylyltransferase revealed via limited proteolysis and mass spectrometry.
Bogan MJ; Agnes GR; Pio F; Cornell RB
J Biol Chem; 2005 May; 280(20):19613-24. PubMed ID: 15713672
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]