BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 30567709)

  • 1. Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance.
    Slater RE; Strom JG; Methawasin M; Liss M; Gotthardt M; Sweitzer N; Granzier HL
    J Gen Physiol; 2019 Jan; 151(1):42-52. PubMed ID: 30567709
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction.
    Methawasin M; Strom JG; Slater RE; Fernandez V; Saripalli C; Granzier H
    Circulation; 2016 Oct; 134(15):1085-1099. PubMed ID: 27630136
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of exercise on passive myocardial stiffness in mice with diastolic dysfunction.
    Slater RE; Strom JG; Granzier H
    J Mol Cell Cardiol; 2017 Jul; 108():24-33. PubMed ID: 28476659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction.
    Hamdani N; Bishu KG; von Frieling-Salewsky M; Redfield MM; Linke WA
    Cardiovasc Res; 2013 Mar; 97(3):464-71. PubMed ID: 23213108
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titin.
    Zile MR; Baicu CF; Ikonomidis JS; Stroud RE; Nietert PJ; Bradshaw AD; Slater R; Palmer BM; Van Buren P; Meyer M; Redfield MM; Bull DA; Granzier HL; LeWinter MM
    Circulation; 2015 Apr; 131(14):1247-59. PubMed ID: 25637629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alternative Splicing of Titin Restores Diastolic Function in an HFpEF-Like Genetic Murine Model (TtnΔIAjxn).
    Bull M; Methawasin M; Strom J; Nair P; Hutchinson K; Granzier H
    Circ Res; 2016 Sep; 119(6):764-72. PubMed ID: 27470639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling.
    Hutchinson KR; Saripalli C; Chung CS; Granzier H
    J Mol Cell Cardiol; 2015 Feb; 79():104-14. PubMed ID: 25450617
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunction.
    Hudson B; Hidalgo C; Saripalli C; Granzier H
    Circ Res; 2011 Sep; 109(8):858-66. PubMed ID: 21835910
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heart rate reduction by If-inhibition improves vascular stiffness and left ventricular systolic and diastolic function in a mouse model of heart failure with preserved ejection fraction.
    Reil JC; Hohl M; Reil GH; Granzier HL; Kratz MT; Kazakov A; Fries P; Müller A; Lenski M; Custodis F; Gräber S; Fröhlig G; Steendijk P; Neuberger HR; Böhm M
    Eur Heart J; 2013 Sep; 34(36):2839-49. PubMed ID: 22833515
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.
    Hinze F; Dieterich C; Radke MH; Granzier H; Gotthardt M
    J Mol Med (Berl); 2016 Dec; 94(12):1349-1358. PubMed ID: 27889803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffness.
    Hudson BD; Hidalgo CG; Gotthardt M; Granzier HL
    J Mol Cell Cardiol; 2010 May; 48(5):972-8. PubMed ID: 20026128
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.
    Hidalgo CG; Chung CS; Saripalli C; Methawasin M; Hutchinson KR; Tsaprailis G; Labeit S; Mattiazzi A; Granzier HL
    J Mol Cell Cardiol; 2013 Jan; 54():90-7. PubMed ID: 23220127
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.
    Granzier HL; Radke MH; Peng J; Westermann D; Nelson OL; Rost K; King NM; Yu Q; Tschöpe C; McNabb M; Larson DF; Labeit S; Gotthardt M
    Circ Res; 2009 Sep; 105(6):557-64. PubMed ID: 19679835
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction.
    Schwarzl M; Hamdani N; Seiler S; Alogna A; Manninger M; Reilly S; Zirngast B; Kirsch A; Steendijk P; Verderber J; Zweiker D; Eller P; Höfler G; Schauer S; Eller K; Maechler H; Pieske BM; Linke WA; Casadei B; Post H
    Am J Physiol Heart Circ Physiol; 2015 Nov; 309(9):H1407-18. PubMed ID: 26342070
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Changes in titin and collagen underlie diastolic stiffness diversity of cardiac muscle.
    Wu Y; Cazorla O; Labeit D; Labeit S; Granzier H
    J Mol Cell Cardiol; 2000 Dec; 32(12):2151-62. PubMed ID: 11112991
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient mice.
    Lee EJ; Peng J; Radke M; Gotthardt M; Granzier HL
    J Mol Cell Cardiol; 2010 Sep; 49(3):449-58. PubMed ID: 20507834
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of exercise training on post-translational and post-transcriptional regulation of titin stiffness in striated muscle of wild type and IG KO mice.
    Hidalgo C; Saripalli C; Granzier HL
    Arch Biochem Biophys; 2014 Jun; 552-553():100-7. PubMed ID: 24603287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mineralocorticoid signaling in transition to heart failure with normal ejection fraction.
    Shapiro BP; Owan TE; Mohammed S; Kruger M; Linke WA; Burnett JC; Redfield MM
    Hypertension; 2008 Feb; 51(2):289-95. PubMed ID: 18086943
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Titin-isoform dependence of titin-actin interaction and its regulation by S100A1/Ca2+ in skinned myocardium.
    Fukushima H; Chung CS; Granzier H
    J Biomed Biotechnol; 2010; 2010():727239. PubMed ID: 20414336
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual Endothelin-A/Endothelin-B Receptor Blockade and Cardiac Remodeling in Heart Failure With Preserved Ejection Fraction.
    Valero-Munoz M; Li S; Wilson RM; Boldbaatar B; Iglarz M; Sam F
    Circ Heart Fail; 2016 Nov; 9(11):. PubMed ID: 27810862
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.