BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 30569119)

  • 1. Inhibition of PIKfyve using YM201636 suppresses the growth of liver cancer via the induction of autophagy.
    Hou JZ; Xi ZQ; Niu J; Li W; Wang X; Liang C; Sun H; Fang D; Xie SQ
    Oncol Rep; 2019 Mar; 41(3):1971-1979. PubMed ID: 30569119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636.
    Sbrissa D; Ikonomov OC; Filios C; Delvecchio K; Shisheva A
    Am J Physiol Cell Physiol; 2012 Aug; 303(4):C436-46. PubMed ID: 22621786
    [TBL] [Abstract][Full Text] [Related]  

  • 3. YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes.
    Ikonomov OC; Sbrissa D; Shisheva A
    Biochem Biophys Res Commun; 2009 May; 382(3):566-70. PubMed ID: 19289105
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation.
    Ikonomov OC; Altankov G; Sbrissa D; Shisheva A
    Toxicol Appl Pharmacol; 2018 Oct; 356():151-158. PubMed ID: 30098992
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells.
    Yang J; Pi C; Wang G
    Biomed Pharmacother; 2018 Jul; 103():699-707. PubMed ID: 29680738
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
    Zhang DM; Liu JS; Deng LJ; Chen MF; Yiu A; Cao HH; Tian HY; Fung KP; Kurihara H; Pan JX; Ye WC
    Carcinogenesis; 2013 Jun; 34(6):1331-42. PubMed ID: 23393227
    [TBL] [Abstract][Full Text] [Related]  

  • 7. OSU-03012, a novel celecoxib derivative, induces reactive oxygen species-related autophagy in hepatocellular carcinoma.
    Gao M; Yeh PY; Lu YS; Hsu CH; Chen KF; Lee WC; Feng WC; Chen CS; Kuo ML; Cheng AL
    Cancer Res; 2008 Nov; 68(22):9348-57. PubMed ID: 19010909
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bigelovin, a sesquiterpene lactone, suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation in liver cancer.
    Wang B; Zhou TY; Nie CH; Wan DL; Zheng SS
    Biochem Biophys Res Commun; 2018 May; 499(2):156-163. PubMed ID: 29548826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effects of PIKfyve inhibitor YM201636 on claudins and malignancy potential of nonsmall cell cancer cells.
    DoĞan E; DÜzgÜn Z; Yildirim Z; Özdİl B; AktuĞ H; Bozok ÇetİntaŞ V
    Turk J Biol; 2021; 45(1):26-34. PubMed ID: 33597819
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The PIKfyve inhibitor YM201636 blocks the continuous recycling of the tight junction proteins claudin-1 and claudin-2 in MDCK cells.
    Dukes JD; Whitley P; Chalmers AD
    PLoS One; 2012; 7(3):e28659. PubMed ID: 22396724
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Capsaicin and sorafenib combination treatment exerts synergistic anti‑hepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling.
    Dai N; Ye R; He Q; Guo P; Chen H; Zhang Q
    Oncol Rep; 2018 Dec; 40(6):3235-3248. PubMed ID: 30272354
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition.
    Sano O; Kazetani K; Funata M; Fukuda Y; Matsui J; Iwata H
    FEBS Lett; 2016 Jun; 590(11):1576-85. PubMed ID: 27135648
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of an oral allosteric AKT inhibitor (MK-2206) on human nasopharyngeal cancer in vitro and in vivo.
    Zhao YY; Tian Y; Zhang J; Xu F; Yang YP; Huang Y; Zhao HY; Zhang JW; Xue C; Lam MH; Yan L; Hu ZH; Dinglin XX; Zhang L
    Drug Des Devel Ther; 2014; 8():1827-37. PubMed ID: 25336925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Angelicin inhibits liver cancer growth in vitro and in vivo.
    Wang F; Li J; Li R; Pan G; Bai M; Huang Q
    Mol Med Rep; 2017 Oct; 16(4):5441-5449. PubMed ID: 28849216
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Small molecule PIKfyve inhibitors as cancer therapeutics: Translational promises and limitations.
    Ikonomov OC; Sbrissa D; Shisheva A
    Toxicol Appl Pharmacol; 2019 Nov; 383():114771. PubMed ID: 31628917
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Akebia saponin E, as a novel PIKfyve inhibitor, induces lysosome-associated cytoplasmic vacuolation to inhibit proliferation of hepatocellular carcinoma cells.
    Peng P; Jia D; Cao L; Lu W; Liu X; Liang C; Pan Z; Fang Z
    J Ethnopharmacol; 2021 Feb; 266():113446. PubMed ID: 33031902
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120's therapeutic effectiveness in lung cancer cells.
    Ren H; Guo H; Thakur A; Zhang S; Wang T; Liang Y; Shi P; Gao L; Liu F; Feng J; Chen T; Yang T; Shang D; Liu JJ; Xu F; Chen M
    Oncotarget; 2016 Oct; 7(41):67277-67287. PubMed ID: 27572309
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comprehensive anti-tumor effect of Brusatol through inhibition of cell viability and promotion of apoptosis caused by autophagy via the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.
    Ye R; Dai N; He Q; Guo P; Xiang Y; Zhang Q; Hong Z; Zhang Q
    Biomed Pharmacother; 2018 Sep; 105():962-973. PubMed ID: 30021391
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resveratrol inhibited the progression of human hepatocellular carcinoma by inducing autophagy via regulating p53 and the phosphoinositide 3‑kinase/protein kinase B pathway.
    Zhang B; Yin X; Sui S
    Oncol Rep; 2018 Nov; 40(5):2758-2765. PubMed ID: 30132535
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PIKfyve regulates the endosomal localization of CpG oligodeoxynucleotides to elicit TLR9-dependent cellular responses.
    Hazeki K; Uehara M; Nigorikawa K; Hazeki O
    PLoS One; 2013; 8(9):e73894. PubMed ID: 24040108
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.