BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 30570184)

  • 1. RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121.
    Sekiguchi T; Furuno N; Ishii T; Hirose E; Sekiguchi F; Wang Y; Kobayashi H
    Genes Cells; 2019 Feb; 24(2):151-161. PubMed ID: 30570184
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway.
    Lee M; Kim JH; Yoon I; Lee C; Fallahi Sichani M; Kang JS; Kang J; Guo M; Lee KY; Han G; Kim S; Han JM
    Proc Natl Acad Sci U S A; 2018 Jun; 115(23):E5279-E5288. PubMed ID: 29784813
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of mTORC1 by the Rag GTPases.
    Lama-Sherpa TD; Jeong MH; Jewell JL
    Biochem Soc Trans; 2023 Apr; 51(2):655-664. PubMed ID: 36929165
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
    Shen K; Sabatini DM
    Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9545-9550. PubMed ID: 30181260
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
    Oshiro N; Rapley J; Avruch J
    J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tissue-specific expression differences in Ras-related GTP-binding proteins in male rats.
    Kincheloe GN; Roberson PA; Jefferson LS; Kimball SR
    Physiol Rep; 2024 Feb; 12(3):e15928. PubMed ID: 38296461
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
    Tsun ZY; Bar-Peled L; Chantranupong L; Zoncu R; Wang T; Kim C; Spooner E; Sabatini DM
    Mol Cell; 2013 Nov; 52(4):495-505. PubMed ID: 24095279
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition.
    Figlia G; Müller S; Hagenston AM; Kleber S; Roiuk M; Quast JP; Ten Bosch N; Carvajal Ibañez D; Mauceri D; Martin-Villalba A; Teleman AA
    Nat Cell Biol; 2022 Sep; 24(9):1407-1421. PubMed ID: 36097071
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RagC phosphorylation autoregulates mTOR complex 1.
    Yang G; Humphrey SJ; Murashige DS; Francis D; Wang QP; Cooke KC; Neely GG; James DE
    EMBO J; 2019 Feb; 38(3):. PubMed ID: 30552228
    [TBL] [Abstract][Full Text] [Related]  

  • 10. WDR35 is involved in subcellular localization of acetylated tubulin in 293T cells.
    Sekiguchi T; Ishii T; Kobayashi H; Furuno N
    Biochem Biophys Res Commun; 2021 Apr; 547():169-175. PubMed ID: 33610917
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for the assembly of the Ragulator-Rag GTPase complex.
    Yonehara R; Nada S; Nakai T; Nakai M; Kitamura A; Ogawa A; Nakatsumi H; Nakayama KI; Li S; Standley DM; Yamashita E; Nakagawa A; Okada M
    Nat Commun; 2017 Nov; 8(1):1625. PubMed ID: 29158492
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.
    Deng L; Jiang C; Chen L; Jin J; Wei J; Zhao L; Chen M; Pan W; Xu Y; Chu H; Wang X; Ge X; Li D; Liao L; Liu M; Li L; Wang P
    Mol Cell; 2015 Jun; 58(5):804-18. PubMed ID: 25936802
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sestrins inhibit mTORC1 kinase activation through the GATOR complex.
    Parmigiani A; Nourbakhsh A; Ding B; Wang W; Kim YC; Akopiants K; Guan KL; Karin M; Budanov AV
    Cell Rep; 2014 Nov; 9(4):1281-91. PubMed ID: 25457612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rag GTPase in amino acid signaling.
    Kim J; Kim E
    Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rag GTPases are cardioprotective by regulating lysosomal function.
    Kim YC; Park HW; Sciarretta S; Mo JS; Jewell JL; Russell RC; Wu X; Sadoshima J; Guan KL
    Nat Commun; 2014 Jul; 5():4241. PubMed ID: 24980141
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
    Anandapadamanaban M; Masson GR; Perisic O; Berndt A; Kaufman J; Johnson CM; Santhanam B; Rogala KB; Sabatini DM; Williams RL
    Science; 2019 Oct; 366(6462):203-210. PubMed ID: 31601764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids.
    Egri SB; Shen K
    J Biol Chem; 2021 Jul; 297(1):100861. PubMed ID: 34116056
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
    Lawrence RE; Fromm SA; Fu Y; Yokom AL; Kim DJ; Thelen AM; Young LN; Lim CY; Samelson AJ; Hurley JH; Zoncu R
    Science; 2019 Nov; 366(6468):971-977. PubMed ID: 31672913
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.
    Chantranupong L; Wolfson RL; Orozco JM; Saxton RA; Scaria SM; Bar-Peled L; Spooner E; Isasa M; Gygi SP; Sabatini DM
    Cell Rep; 2014 Oct; 9(1):1-8. PubMed ID: 25263562
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RagA, but not RagB, is essential for embryonic development and adult mice.
    Efeyan A; Schweitzer LD; Bilate AM; Chang S; Kirak O; Lamming DW; Sabatini DM
    Dev Cell; 2014 May; 29(3):321-9. PubMed ID: 24768164
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.