211 related articles for article (PubMed ID: 30571123)
1. Synthesis, Biological, and Structural Explorations of New Zwitterionic Derivatives of 14- O-Methyloxymorphone, as Potent μ/δ Opioid Agonists and Peripherally Selective Antinociceptives.
Spetea M; Rief SB; Haddou TB; Fink M; Kristeva E; Mittendorfer H; Haas S; Hummer N; Follia V; Guerrieri E; Asim MF; Sturm S; Schmidhammer H
J Med Chem; 2019 Jan; 62(2):641-653. PubMed ID: 30571123
[TBL] [Abstract][Full Text] [Related]
2. Novel approach to demonstrate high efficacy of mu opioids in the rat vas deferens: a simple model of predictive value.
Riba P; Friedmann T; Király KP; Al-Khrasani M; Sobor M; Asim MF; Spetea M; Schmidhammer H; Furst S
Brain Res Bull; 2010 Jan; 81(1):178-84. PubMed ID: 19800397
[TBL] [Abstract][Full Text] [Related]
3. Benzylideneoxymorphone: A new lead for development of bifunctional mu/delta opioid receptor ligands.
Healy JR; Bezawada P; Griggs NW; Devereaux AL; Matsumoto RR; Traynor JR; Coop A; Cunningham CW
Bioorg Med Chem Lett; 2017 Feb; 27(3):666-669. PubMed ID: 28011222
[TBL] [Abstract][Full Text] [Related]
4. Local peripheral antinociceptive effects of 14-O-methyloxymorphone derivatives in inflammatory and neuropathic pain in the rat.
Obara I; Makuch W; Spetea M; Schütz J; Schmidhammer H; Przewlocki R; Przewlocka B
Eur J Pharmacol; 2007 Mar; 558(1-3):60-7. PubMed ID: 17204264
[TBL] [Abstract][Full Text] [Related]
5. Recent advances in the development of 14-alkoxy substituted morphinans as potent and safer opioid analgesics.
Spetea M; Schmidhammer H
Curr Med Chem; 2012; 19(15):2442-57. PubMed ID: 22455592
[TBL] [Abstract][Full Text] [Related]
6. Bioactivity of new mu and delta opioid peptides.
Capasso A
Med Chem; 2007 Sep; 3(5):480-7. PubMed ID: 17897075
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of 14-alkoxymorphinans. 22.(1) Influence of the 14-alkoxy group and the substitution in position 5 in 14-alkoxymorphinan-6-ones on in vitro and in vivo activities.
Lattanzi R; Spetea M; Schüllner F; Rief SB; Krassnig R; Negri L; Schmidhammer H
J Med Chem; 2005 May; 48(9):3372-8. PubMed ID: 15857143
[TBL] [Abstract][Full Text] [Related]
8. Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice.
Yang PP; Yeh GC; Yeh TK; Xi J; Loh HH; Law PY; Tao PL
Pharmacol Res; 2016 Sep; 111():867-876. PubMed ID: 27496654
[TBL] [Abstract][Full Text] [Related]
9. N-Phenethyl Substitution in 14-Methoxy-N-methylmorphinan-6-ones Turns Selective µ Opioid Receptor Ligands into Dual µ/δ Opioid Receptor Agonists.
Dumitrascuta M; Bermudez M; Ben Haddou T; Guerrieri E; Schläfer L; Ritsch A; Hosztafi S; Lantero A; Kreutz C; Massotte D; Schmidhammer H; Wolber G; Spetea M
Sci Rep; 2020 Mar; 10(1):5653. PubMed ID: 32221355
[TBL] [Abstract][Full Text] [Related]
10. Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective mu or delta opioid agonists in mice.
Bilsky EJ; Inturrisi CE; Sadée W; Hruby VJ; Porreca F
Pain; 1996 Dec; 68(2-3):229-37. PubMed ID: 9121809
[TBL] [Abstract][Full Text] [Related]
11. Dual Pharmacophores Explored via Structure-Activity Relationship (SAR) Matrix: Insights into Potent, Bifunctional Opioid Ligand Design.
Nastase AF; Anand JP; Bender AM; Montgomery D; Griggs NW; Fernandez TJ; Jutkiewicz EM; Traynor JR; Mosberg HI
J Med Chem; 2019 Apr; 62(8):4193-4203. PubMed ID: 30916966
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects.
Vekariya RH; Lei W; Ray A; Saini SK; Zhang S; Molnar G; Barlow D; Karlage KL; Bilsky EJ; Houseknecht KL; Largent-Milnes TM; Streicher JM; Ananthan S
J Med Chem; 2020 Jul; 63(14):7663-7694. PubMed ID: 32530286
[TBL] [Abstract][Full Text] [Related]
13. Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand.
Parenti C; Turnaturi R; Aricò G; Marrazzo A; Prezzavento O; Ronsisvalle S; Scoto GM; Ronsisvalle G; Pasquinucci L
Life Sci; 2012 Jun; 90(25-26):957-61. PubMed ID: 22580287
[TBL] [Abstract][Full Text] [Related]
14. Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation.
Pasquinucci L; Turnaturi R; Montenegro L; Caraci F; Chiechio S; Parenti C
Eur J Pharmacol; 2019 Mar; 847():97-102. PubMed ID: 30690004
[TBL] [Abstract][Full Text] [Related]
15. Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors.
Yadlapalli JSK; Ford BM; Ketkar A; Wan A; Penthala NR; Eoff RL; Prather PL; Dobretsov M; Crooks PA
Pharmacol Res; 2016 Nov; 113(Pt A):335-347. PubMed ID: 27637375
[TBL] [Abstract][Full Text] [Related]
16. In vitro opioid activity profiles of 6-amino acid substituted derivatives of 14-O-methyloxymorphone.
Spetea M; Friedmann T; Riba P; Schütz J; Wunder G; Langer T; Schmidhammer H; Fürst S
Eur J Pharmacol; 2004 Jan; 483(2-3):301-8. PubMed ID: 14729121
[TBL] [Abstract][Full Text] [Related]
17. Pyrrolo- and pyridomorphinans: non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists.
Kumar V; Clark MJ; Traynor JR; Lewis JW; Husbands SM
Bioorg Med Chem; 2014 Aug; 22(15):4067-72. PubMed ID: 24973818
[TBL] [Abstract][Full Text] [Related]
18. Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays.
Bonner GG; Davis P; Stropova D; Edsall S; Yamamura HI; Porreca F; Hruby VJ
J Med Chem; 2000 Feb; 43(4):569-80. PubMed ID: 10691683
[TBL] [Abstract][Full Text] [Related]
19. Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat.
Fürst S; Riba P; Friedmann T; Tímar J; Al-Khrasani M; Obara I; Makuch W; Spetea M; Schütz J; Przewlocki R; Przewlocka B; Schmidhammer H
J Pharmacol Exp Ther; 2005 Feb; 312(2):609-18. PubMed ID: 15383636
[TBL] [Abstract][Full Text] [Related]
20. Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities at μ (MOR), δ (DOR), and κ (KOR) Opioid Receptors.
Eans SO; Ganno ML; Mizrachi E; Houghten RA; Dooley CT; McLaughlin JP; Nefzi A
J Med Chem; 2015 Jun; 58(12):4905-17. PubMed ID: 25996309
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
